Abstract: The present invention relates to a method of providing a reaction chamber (10) for a laser evaporation system (100), the reaction chamber (10) comprising at least one wall section (20) with an inner surface (22) facing a reaction volume (12) of the laser evaporation system (100). In addition, the present invention relates to a reaction chamber (10) for a laser evaporation system (100), the reaction chamber (10) comprising at least one wall section (20) with an inner surface (22) enclosing a reaction volume (12). Further, the present invention relates to a laser evaporation system (100) comprising a reaction chamber (10).

Abstract: A helical gear transmission for an electromechanical servo steering mechanism may include a shaft that meshes with a helical gear. The shaft may be arranged in a transmission housing and, at its first end, may be mounted in a drive-side bearing arrangement so as to be rotatable about an axis of rotation. At its second end, the shaft may be mounted in a drive-remote bearing arrangement in the transmission housing. The drive-side bearing arrangement may have a rolling bearing, an outer ring of which is spherical. The rolling bearing may be enclosed by two bearing shells. The outer side of the outer ring may have two flat points that are opposite one another and form a pivot axis about which the shaft is pivotable in a direction of the helical gear.

Abstract: The present invention relates to oligonucleotides that upregulate or restore the expression of progranulin in cells by targeting the promoter region of the progranulin gene. The invention further relates to pharmaceutical compositions and methods for the treatment of diseases associated with progranulin, specifically progranulin haploinsufficiency and neurological disorders.

Abstract: A helical gear transmission for an electromechanical servo steering mechanism may include a shaft that meshes with a helical gear. The shaft may be arranged in a transmission housing and, at its first end, may be mounted in a drive-side bearing arrangement so as to be rotatable about an axis of rotation. At its second end, the shaft may be mounted in a drive-remote bearing arrangement in the transmission housing. The drive-side bearing arrangement may have a rolling bearing, an outer ring of which is spherical. The rolling bearing may be enclosed by two bearing shells. The outer side of the outer ring may have two flat points that are opposite one another and form a pivot axis about which the shaft is pivotable in a direction of the helical gear.

Abstract: Systems and methods to predict bidding behavior are described. The system identifies a listing that includes listing information that describes an item that is being auctioned on a network-based marketplace. The system further identifies bid classification information based on the number of bids received for the item. Finally, the system predicts whether no more bids are expected to be received for the item based on the classification information.

Abstract: Systems and methods to predict bidding behaviour are described. The system identifies a listing that includes listing information that describes an item that is being auctioned on a network-based marketplace. The system further identifies bid classification information based on the number of bids received for the item. Finally, the system predicts whether no more bids are expected to be received for the item based on the classification information.

Abstract: The magnitude of torque which can be transmitted by a bypass clutch between the housing and the turbine of a torque converter between a prime mover, such as an engine, and an automatic transmission in the power train of a motor vehicle is selectively regulatable by a computerized regulating unit. The regulation involves the transmission of torque by the clutch in dependency upon the magnitude of the torque being transmitted by the output element of the engine and ascertaining as well as adaptively applying to the clutch a variable force so that the clutch can transmit a predetermined torque. This entails automatic selection of a minimum slip between a torque receiving and a torque transmitting part of the power train. Compensation, particularly long-range compensation, is carried out for the existence of possible differences between the predetermined and actual torques being transmitted by the clutch.

Abstract: A fluid-operated system which can supply a pressurized fluid (e.g., oil) to one or more adjustable consumers (such as a clutch and/or a transmission) in a motor vehicle. The system employs one or more fluid pressurizing pumps and/or accumulators and an arrangement of valves in a path for pressurized fluid from the pressurizing unit(s) to the consumer(s). The valves can vary the fluid pressure in dependency upon at least one variable (such variable can be selected by a control unit in conjunction with an actor). In accordance with one presently preferred embodiment, the valves can cooperate with one or more flow restrictors to impart to the fluid in the path a first pressure within a first range of varying pressures as a first function of the at least one variable, and a second pressure within a second range of varying pressures as a different second function of the at least one variable. One of the valves can be embodied in or located outside of the mobile valving element and/or housing of another valve.

Abstract: A method of aseptically packaging pre-sterilized foodstuffs is described. The method used `dry` radiation methods for sterilizing packaging material in an aseptic workspace either before or after construction of the container as such. The internal surfaces of the packaging material supplied to the workspace are coated with a radiation resistant lacquer. After sterilization the containers are filled with food such as milk or yoghurt and heat sealed.