Patents by Inventor Johannes C. van Groeninghen

Johannes C. van Groeninghen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8962558
    Abstract: A method for recognizing and evaluating the presence and function of GnRH receptors on tumor cells including those originating in the brain and/or nervous system and/or the meninges and/or reactive neuroglia cells and/or primitive neuroectodermal tumor cells and/or on Kaposi sarcoma is provided. Furthermore, a method for reducing degenerate GnRH-positive tumor cells and/or for decreasing cellular replication of the above GnRH-positive tumor cells comprising administering to a cell or to a subject a replication decreasing amount of a GnRH agonist and/or GnRH antagonist and/or an erythropoietin agonist, and/or a thrombopoietin agonist, and/or a endothelin antagonist and/or a gonadotropin inhibiting hormone agonist is also provided. Furthermore, a diagnostic kit for detecting GnRH receptors on tumor cells according to the present methods is disclosed.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: February 24, 2015
    Inventor: Johannes C. Van Groeninghen
  • Publication number: 20120238494
    Abstract: A method for recognizing and evaluating the presence and function of GnRH receptors on tumor cells including those originating in the brain and/or nervous system and/or the meninges and/or reactive neuroglia cells and/or primitive neuroectodermal tumor cells and/or on Kaposi sarcoma is provided. Furthermore, a method for reducing degenerate GnRH-positive tumor cells and/or for decreasing cellular replication of the above GnRH-positive tumor cells comprising administering to a cell or to a subject a replication decreasing amount of a GnRH agonist and/or GnRH antagonist and/or an erythropoietin agonist, and/or a thrombopoietin agonist, and/or a endothelin antagonist and/or a gonadotropin inhibiting hormone agonist is also provided. Furthermore, a diagnostic kit for detecting GnRH receptors on tumor cells according to the present methods is disclosed.
    Type: Application
    Filed: March 27, 2012
    Publication date: September 20, 2012
    Inventor: JOHANNES C. VAN GROENINGHEN
  • Publication number: 20100190692
    Abstract: A method for recognizing and evaluating the presence and function of GnRH receptors on tumor cells originating in the brain and/or nervous system and/or the meninges and/or reactive neuroglia cells and/or primitive neuroectodermal tumor cells and/or on Kaposi sarcoma is provided. Furthermore a method for reducing degenerate GnRH-positive tumor cells and/or for decreasing cellular replication of the above GnRH-positive tumor cells comprising administering to a cell or to a subject a replication decreasing amount of a GnRH agonist and/or GnRH antagonist and/or an erythropoietin agonist, and/or a thrombopoietin agonist, and/or a endothelin antagonist and/or a gonadotropin inhibiting hormone agonist is also provided. Furthermore, a diagnostic kit for detecting GnRH receptors on tumor cells according to the present methods is disclosed.
    Type: Application
    Filed: February 5, 2010
    Publication date: July 29, 2010
    Inventor: JOHANNES C. VAN GROENINGHEN
  • Patent number: 7695722
    Abstract: A method for recognizing and determining GnRH receptors on abnormal cells of a tumor originating in the brain and/or nervous system and/or the meninges and/or on Kaposi sarcoma. Also, preparing diagnostic kits for tumors originating in the brain and/or nervous system and/or the meninges and/or for Kaposi sarcoma. Further, a method for decreasing cellular replication of GnRH-positive glioma, oat-cell carcinoma, malignant melanoma, or Kaposi sarcoma comprising administering to a cell or to a subject a replication decreasing amount of a GnRH agonist.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: April 13, 2010
    Inventor: Johannes C. van Groeninghen