Patents by Inventor Johannes E. Van Lier

Johannes E. Van Lier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amphiphilic trisulfonated porphyrazines for photodynamic applications in medicine
    Patent number: 7541457
    Abstract: Disclosed herein are novel trisulfonated tribenzo-mononahptho-porphyrazines, processes for making them and their application as improved photosensitizing drugs for the treatment of various medical conditions by photodynamic therapy (PDT). These water-soluble amphiphilic porphyrazines are substituted with different alkylyl, aryl, aminoalkyl and aminoaryl groups, with or without carboxyl moeity.
    Type: Grant
    Filed: May 14, 2004
    Date of Patent: June 2, 2009
    Assignee: Universite de Sherbrooke
    Inventors: Johannes E. Van Lier, Haroutioun Minas Hasséssian, Hongjian Tian, Nicole Cauchon, Hasrat Ali
  • Radiometal complexes of 2-pyrrolylthiones and their use as radiopharmaceuticals for imaging and therapy
    Publication number: 20040044065
    Abstract: Novel 2-pyrrolylthione derived metal chelate compounds are disclosed as imaging and therapeutic agents. Compositions and methods for their preparation and use as diagnostic imaging and therapeutic agents are also disclosed.
    Type: Application
    Filed: August 29, 2003
    Publication date: March 4, 2004
    Inventors: David H. Dolphin, Svetlana V. Kudrevich, Svetlana V. Selivanova, Jacques Rousseau, Johannes E. Van Lier
  • Radiometal complexes of 2-pyrrolylthiones and their use as radiopharmaceuticals for imaging and therapy
    Patent number: 6613304
    Abstract: Novel 2-pyrrolylthione derived metal chelate compounds are disclosed as imaging and therapeutic agents. Compositions and methods for their preparation and use as diagnostic imaging and therapeutic agents are also disclosed.
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: September 2, 2003
    Assignees: University of British Columbia, Universite de Sherbrooke
    Inventors: David H. Dolphin, Svetlana V. Kudrevich, Svetlana V. Selivanova, Jacques Rousseau, Johannes E. Van Lier
  • Radiometal complexes of 2-pyrrolylthiones and their use as radiopharmaceuticals for imaging and therapy
    Publication number: 20020102209
    Abstract: Novel 2-pyrrolylthione derived metal chelate compounds are disclosed as imaging and therapeutic agents. Compositions and methods for their preparation and use as diagnostic imaging and therapeutic agents are also disclosed.
    Type: Application
    Filed: April 20, 2001
    Publication date: August 1, 2002
    Inventors: David H. Dolphin, Svetlana V. Kudrevich, Svetlana V. Selivanova, Jacques Rousseau, Johannes E. Van Lier
  • Syntheses of trisulfonated phthalocyanines and their derivatatives using boron (111) subphthalocyanines as intermediates
    Patent number: 5864044
    Abstract: Disclosed herein are novel trisulfonated phathalocyanines, processes for making them and their derivatives. Also disclosed are key intermediates consisting of Boron(III) subphathalocyanines. Further disclosed are novel uses for various water soluble trisulfophathalocyanines, trisulfobenzonapthoporphyrazines and trisulfonated phathalocyanines. The new uses are directed to photsensitizers for the photodynamic therapy of cancer, the inactivation of viruses in stored blood, organic semiconductors, disk memory material or as materials for gas sensors. In the compounds of the present invention, the central metal atom may be Zn, Co(II), Ni or Cu(II).
    Type: Grant
    Filed: July 24, 1997
    Date of Patent: January 26, 1999
    Assignee: Universite de Sherbrooke
    Inventors: Johannes E. Van Lier, Svetlana V. Kudrevich, Sandra Gilbert