Patents by Inventor Johannes Franciscus Van Den Bosch

Johannes Franciscus Van Den Bosch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6790446
    Abstract: The present invention relates to vaccines comprising antiserum raised against a flagellaless Campylobacter strain for the prevention of Campylobacter colonization in animals. The invention also relates to antigenic Campylobacter proteins visible in a Western blot of Campylobacter jejuni protein after incubation of said Western blot with antibodies against a flagellaless mutant of Campylobacter jejuni and not visible after incubation of said blot with antibodies against wild type Campylobacter jejuni, and to their use in vaccines and the manufacturing thereof. The invention further relates to vaccines comprising such proteins and antibodies against such proteins. The invention further relates to the use of such Campylobacter proteins and to antiserum and antibodies raised against Campylobacter antigens for the preparation of vaccines. Finally, the invention relates to methods for the preparation of such vaccines.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: September 14, 2004
    Assignee: Akzo Nobel, NV
    Inventors: Antonius Arnoldus Christiaan Jacobs, Johannes Franciscus van den Bosch, Petrus Johannes Maria Nuijten
  • Patent number: 6787137
    Abstract: The present invention relates to vaccines comprising antiserum raised against a flagellaless Campylobacter strain for the prevention of Campylobacter colonisation in animals. The invention also relates to antigenic Campylobacter proteins visible in a Western blot of Campylobacter jejuni protein after incubation of said Western blot with antibodies against a flagellaless mutant of Campylobacter jejuni and not visible after incubation of said blot with antibodies against wild type Campylobacter jejuni, and to their use in vaccines and the manufacturing thereof. The invention further relates to vaccines comprising such proteins and antibodies against such proteins. The invention further relates to the use of such Campylobacter proteins and to antiserum and antibodies raised against Campylobacter antigens for the preparation of vaccines. Finally, the invention relates to methods for the preparation of such vaccines.
    Type: Grant
    Filed: April 7, 2000
    Date of Patent: September 7, 2004
    Assignee: Akzo Nobel N. V.
    Inventors: Antonius Arnoldus Christiaan Jacobs, Johannes Franciscus van den Bosch, Petrus Johannes Maria Nuijten
  • Patent number: 6770275
    Abstract: The present invention relates to live attenuated RTX-toxin producing bacteria of the family Pasteurellaceae, of which the attenuation is due to the fact that they produce RTX toxin in a non-activated form. The invention also relates to vaccines for the protection of mammals against infection with RTX-toxin producing bacteria of the family Pasteurellaceae, and to methods for the preparation of said live attenuated bacteria and vaccines.
    Type: Grant
    Filed: May 30, 1997
    Date of Patent: August 3, 2004
    Assignee: Akzo Nobel N.V.
    Inventors: Ruud Philip Antoon Maria Segers, Johannes Franciscus Van Den Bosch, Joachim Frey
  • Publication number: 20030072766
    Abstract: The present invention relates to vaccines comprising antiserum raised against a flagellaless Campylobacter strain for the prevention of Campylobacter colonisation in animals. The invention also relates to antigenic Campylobacter proteins visible in a Western blot of Campylobacter jejuni protein after incubation of said Western blot with antibodies against a flagellaless mutant of Campylobacter jejuni and not visible after incubation of said blot with antibodies against wild type Campylobacter jejuni, and to their use in vaccines and the manufacturing thereof. The invention further relates to vaccines comprising such proteins and antibodies against such proteins. The invention further relates to the use of such Campylobacter proteins and to antiserum and antibodies raised against Campylobacter antigens for the preparation of vaccines. Finally, the invention relates to methods for the preparation of such vaccines.
    Type: Application
    Filed: July 10, 2002
    Publication date: April 17, 2003
    Inventors: Antonius Arnoldus Christiaan Jacobs, Johannes Franciscus Van Den Bosch, Petrus Johannes Maria Nuijten
  • Patent number: 5750115
    Abstract: According to the present invention it has been found that a novel E. coli toxin or an immunogenic fragment thereof can be used in the preparation of vaccines for warm-blooded animals, and in particular for birds. Said toxin is found to be associated in flagellar structures attached to the bacteria, and these flagella or the free toxins can, after inactivation be used to immunize animals against E. coli infections.
    Type: Grant
    Filed: April 10, 1995
    Date of Patent: May 12, 1998
    Assignee: Akzo Nobel N. V.
    Inventor: Johannes Franciscus Van Den Bosch
  • Patent number: 5648081
    Abstract: The present invention is concerned with vaccines effective in protecting pigs against porcine pleuropneumonia. Said vaccines comprising a hemolysin and/or macrophage toxin and a 42 kD OMP preparation derived from Actinobacillus pleuropneumoniae (App) cells induce a complete and heterologous protection against App infection.
    Type: Grant
    Filed: January 3, 1995
    Date of Patent: July 15, 1997
    Assignee: Akzo Nobel N.V.
    Inventor: Johannes Franciscus van den Bosch