Abstract: The invention relates to methods and means for regulating gene expression and to CodY target sequences. CodY represses its target genes by binding to specific DNA sequences upstream of the respective genes. A conserved target site was identified by analyzing upstream sequences of derepressed genes in a delta codY L. lactis MG1363 derivative, as identified in a DNA micro-array study. Also, CodY target sequences from other gram-positive bacteria, like B. subtilis and Streptococcus are disclosed. Hence, the invention provides CodY target sequences that may be used in different applications to repress or derepress gene expression.

Abstract: A modular plug comprises an insulative housing having a plurality of contacts that have a mating portion and an insulation piercing portion similar to that of conventional modular plugs where the terminals are further provided with capacitor plate portions that are connected to the mating portions via linking portions which cross-over that of an adjacent contact, for at least some of the terminals, in order to provide capacitive coupling between certain contacts to reduce cross-talk.