Patents by Inventor Johannes Heinrich

Johannes Heinrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210121962
    Abstract: A sintering press for producing a sintered connection between a first connection partner and a second connection partner disposed thereabove, having a suction-fixing installation for fixing the first connection partner, having a compression piece which is disposed above the suction-fixing installation.
    Type: Application
    Filed: September 15, 2020
    Publication date: April 29, 2021
    Applicant: SEMIKRON ELEKTRONIK GMBH & CO. KG
    Inventors: DOMINIC BIRKICHT, Juri Heinrich, Thomas Franz, Rudi Ludwig, Silke Kraft, Erik Michaelsen, Johannes Weickmann
  • Publication number: 20200338359
    Abstract: The subject-matter of the present invention is a method for reversibly releasing stem cells from bone marrow niches into peripheral blood and isolating these stem cells. Further, the present invention relates to stem cells obtained in this manner and their use in the medical treatment.
    Type: Application
    Filed: November 2, 2018
    Publication date: October 29, 2020
    Applicant: Roemer & Heigl GmbH
    Inventors: Ramona ROEMER, Johannes Heinrich ESS
  • Patent number: 10415045
    Abstract: The present invention provides a new fungal production system comprising a fungal host strain of Chrysosporium lucknowense wherein the endogenous cellulase secretion is less than 20% of the endogenous cellulase secretion of Chrysosporium lucknowense strain UV 18-25. Preferably, also the secretion of endogenous protease, endogenous ?-glucanase and endogenous cellobiohydrolase is less than 20% of the secretion of Chrysosporium lucknowense strain UV 18-25. Furthermore, fungal host strains are provided wherein several genes have been disrupted. According to another aspect of the invention a method for homologous and/or heterologous production of a pure protein with a purity of higher than 75%, comprising expressing a gene encoding said protein in the strains according to the invention have been described. Furthermore, a method for production of artificial protein mixes comprising expressing a gene encoding each of said proteins in a strain according to the invention have been disclosed.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: September 17, 2019
    Assignee: DANISCO US INC
    Inventors: Peter J. Punt, Richard Paul Burlingame, Christine M. Pynnonen, Phillip T. Olson, Jan Wery, Johannes Heinrich Visser, Mark A. Emalfarb, Jacob Visser, Jan Cornelis Verdoes
  • Patent number: 10072267
    Abstract: Provided are cells having an increased protein production characterized in that said cell comprises modified SUMOylation, a process for producing such a cell or expression system and the use of such a cell in producing a protein of interest.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: September 11, 2018
    Assignee: DANISCO US INC
    Inventors: Jurian Alexander Bronkhof, Jean-Paul Meijnen, Carola Bianca Michielse, Ismail Atalay Van Der Burgt, Jacob Visser, Johannes Heinrich Visser
  • Patent number: 9796603
    Abstract: The invention provides, in one aspect, a system for recirculating ozonated liquid. The system includes a contactor including at least two inlets and at least two outlets. The contactor is in fluid communication with a first liquid source at a first contactor inlet and a second liquid source at a second contactor inlet, and the second contactor inlet receives gas that purges at least a portion of gas from liquid received at the first contactor inlet. The purged gas exits the contactor at a first contactor outlet. The contactor is in fluid communication with the second liquid source at a second contactor outlet, and the contactor drains at least a portion of the liquid in the contactor, the drained liquid exiting the contactor at the second contactor outlet. The contactor includes a third inlet in fluid communication with the first liquid source, the third inlet allowing the first liquid source to release liquid at an ambient pressure.
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: October 24, 2017
    Assignee: MKS Instruments, Inc.
    Inventors: Johannes Heinrich Seiwert, Ulrich Alfred Brammer, Martin Blacha, Gerhard Joachim Schnaiter
  • Publication number: 20170240909
    Abstract: Provided are cells having an increased protein production characterized in that said cell comprises modified SUMOylation, a process for producing such a cell or expression system and the use of such a cell in producing a protein of interest.
    Type: Application
    Filed: February 22, 2017
    Publication date: August 24, 2017
    Inventors: JURIAN ALEXANDER BRONKHOF, JEAN-PAUL MEIJNEN, CAROLA BIANCA MICHIELSE, ISMAIL ATALAY VAN DER BURGT, JACOB VISSER, JOHANNES HEINRICH VISSER
  • Publication number: 20170144894
    Abstract: The invention provides, in one aspect, a system for recirculating ozonated liquid. The system includes a contactor including at least two inlets and at least two outlets. The contactor is in fluid communication with a first liquid source at a first contactor inlet and a second liquid source at a second contactor inlet, and the second contactor inlet receives gas that purges at least a portion of gas from liquid received at the first contactor inlet. The purged gas exits the contactor at a first contactor outlet. The contactor is in fluid communication with the second liquid source at a second contactor outlet, and the contactor drains at least a portion of the liquid in the contactor, the drained liquid exiting the contactor at the second contactor outlet. The contactor includes a third inlet in fluid communication with the first liquid source, the third inlet allowing the first liquid source to release liquid at an ambient pressure.
    Type: Application
    Filed: February 2, 2017
    Publication date: May 25, 2017
    Inventors: Johannes Heinrich Seiwert, Ulrich Alfred Brammer, Martin Blacha, Gerhard Joachim Schnaiter
  • Patent number: 9597613
    Abstract: The invention provides, in one aspect, a system for recirculating ozonated liquid. The system includes a contactor including at least two inlets and at least two outlets. The contactor is in fluid communication with a first liquid source at a first contactor inlet and a second liquid source at a second contactor inlet, and the second contactor inlet receives gas that purges at least a portion of gas from liquid received at the first contactor inlet. The purged gas exits the contactor at a first contactor outlet. The contactor is in fluid communication with the second liquid source at a second contactor outlet, and the contactor drains at least a portion of the liquid in the contactor, the drained liquid exiting the contactor at the second contactor outlet. The contactor includes a third inlet in fluid communication with the first liquid source, the third inlet allowing the first liquid source to release liquid at an ambient pressure.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: March 21, 2017
    Assignee: MKS Instruments, Inc.
    Inventors: Johannes Heinrich Seiwert, Ulrich Alfred Brammer, Martin Blacha, Gerhard Joachim Schnaiter
  • Publication number: 20150376629
    Abstract: The present invention provides a new fungal production system comprising a fungal host strain of Chrysosporium lucknowense wherein the endogenous cellulase secretion is less than 20% of the endogenous cellulase secretion of Chrysosporium lucknowense strain UV 18-25. Preferably, also the secretion of endogenous protease, endogenous ?-glucanase and endogenous cellobiohydrolase is less than 20% of the secretion of Chrysosporium lucknowense strain UV 18-25. Furthermore, fungal host strains are provided wherein several genes have been disrupted. According to another aspect of the invention a method for homologous and/or heterologous production of a pure protein with a purity of higher than 75%, comprising expressing a gene encoding said protein in the strains according to the invention have been described. Furthermore, a method for production of artificial protein mixes comprising expressing a gene encoding each of said proteins in a strain according to the invention have been disclosed.
    Type: Application
    Filed: September 9, 2015
    Publication date: December 31, 2015
    Inventors: Peter J. PUNT, Richard Paul BURLINGAME, Christine M. PYNNONEN, Phillip T. OLSON, Jan WERY, Johannes Heinrich VISSER, Mark A. EMALFARB, Jacob VISSER, Jan Cornelis VERDOES, Jacoba VERDOES
  • Publication number: 20150315037
    Abstract: The invention provides, in one aspect, a system for recirculating ozonated liquid. The system includes a contactor including at least two inlets and at least two outlets. The contactor is in fluid communication with a first liquid source at a first contactor inlet and a second liquid source at a second contactor inlet, and the second contactor inlet receives gas that purges at least a portion of gas from liquid received at the first contactor inlet. The purged gas exits the contactor at a first contactor outlet. The contactor is in fluid communication with the second liquid source at a second contactor outlet, and the contactor drains at least a portion of the liquid in the contactor, the drained liquid exiting the contactor at the second contactor outlet. The contactor includes a third inlet in fluid communication with the first liquid source, the third inlet allowing the first liquid source to release liquid at an ambient pressure.
    Type: Application
    Filed: May 12, 2015
    Publication date: November 5, 2015
    Inventors: Johannes Heinrich Seiwert, Ulrich Alfred Brammer, Martin Blacha, Gerhard Joachim Schnaiter
  • Patent number: 9175296
    Abstract: The present invention provides a new fungal production system comprising a fungal host strain of Chrysosporium lucknowense wherein the endogenous cellulase secretion is less than 20% of the endogenous cellulase secretion of Chrysosporium lucknowense strain UV 18-25. Preferably, also the secretion of endogenous protease, endogenous ?-glucanase and endogenous cellobiohydrolase is less than 20% of the secretion of Chrysosporium lucknowense strain UV 18-25. Furthermore, fungal host strains are provided wherein several genes have been disrupted. According to another aspect of the invention a method for homologous and/or heterologous production of a pure protein with a purity of higher than 75%, comprising expressing a gene encoding said protein in the strains according to the invention have been described. Furthermore, a method for production of artificial protein mixes comprising expressing a gene encoding each of said proteins in a strain according to the invention have been disclosed.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: November 3, 2015
    Assignee: DYADIC NEDERLAND B.V.
    Inventors: Peter J. Punt, Richard Paul Burlingame, Christine M. Pynnonen, Phillip T. Olson, Jan Wery, Johannes Heinrich Visser, Mark A. Emalfarb, Jacob Visser, Jan Cornelis Verdoes, Jacoba Verdoes
  • Publication number: 20150265470
    Abstract: A method of performing a capsulotomy comprises applying a light-absorbing agent to a lens capsule of an eye 1; illuminating the lens capsule using a first light beam and recording an image of the lens capsule using a camera 43; analyzing the recorded image and determining whether the light absorbing agent has been correctly applied to the lens capsule; if it is determined that the light absorbing agent has been correctly applied to the lens capsule, directing a shaped second light beam 19 onto a predetermined line on the lens capsule in order to modify a structure of a tissue of the lens capsule. The first light beam can be generated by defocusing the second light beam using a lens 37.
    Type: Application
    Filed: March 18, 2015
    Publication date: September 24, 2015
    Inventors: Marco WILZBACH, Artur HOEGELE, Michael Stefan RILL, Joachim STEFFEN, Frederik SIEGMANN, Johannes Heinrich KINDT
  • Publication number: 20150265468
    Abstract: A surgical system for opening the lens capsule in an eye includes an application instrument introducible into the anterior chamber of the eye through an incision in the cornea and/or in the sclera. The application instrument has a contact body that is placeable against the anterior capsular wall of the lens capsule of the eye. Light provided by a light source for generating heat in a contact zone of the capsular wall contacting the contact body is appliable to the contact body. The heat has thermal energy that coagulates the biological tissue in the contact zone.
    Type: Application
    Filed: March 22, 2015
    Publication date: September 24, 2015
    Inventors: Joachim Steffen, Marco Wilzbach, Michael Stefan Rill, Johannes Heinrich Kindt
  • Patent number: 9056262
    Abstract: The invention provides, in one aspect, a system for recirculating ozonated liquid. The system includes a contactor including at least two inlets and at least two outlets. The contactor is in fluid communication with a first liquid source at a first contactor inlet and a second liquid source at a second contactor inlet, and the second contactor inlet receives gas that purges at least a portion of gas from liquid received at the first contactor inlet. The purged gas exits the contactor at a first contactor outlet. The contactor is in fluid communication with the second liquid source at a second contactor outlet, and the contactor drains at least a portion of the liquid in the contactor, the drained liquid exiting the contactor at the second contactor outlet. The contactor includes a third inlet in fluid communication with the first liquid source, the third inlet allowing the first liquid source to release liquid at an ambient pressure.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: June 16, 2015
    Assignee: MKS Instruments, Inc.
    Inventors: Johannes Heinrich Seiwert, Ulrich Alfred Brammer, Martin Blacha, Gerhard Joachim Schnaiter
  • Publication number: 20140124036
    Abstract: The invention provides, in one aspect, a system for recirculating ozonated liquid. The system includes a contactor including at least two inlets and at least two outlets. The contactor is in fluid communication with a first liquid source at a first contactor inlet and a second liquid source at a second contactor inlet, and the second contactor inlet receives gas that purges at least a portion of gas from liquid received at the first contactor inlet. The purged gas exits the contactor at a first contactor outlet. The contactor is in fluid communication with the second liquid source at a second contactor outlet, and the contactor drains at least a portion of the liquid in the contactor, the drained liquid exiting the contactor at the second contactor outlet. The contactor includes a third inlet in fluid communication with the first liquid source, the third inlet allowing the first liquid source to release liquid at an ambient pressure.
    Type: Application
    Filed: March 15, 2013
    Publication date: May 8, 2014
    Inventors: Johannes Heinrich Seiwert, Ulrich Alfred Brammer, Martin Blacha, Gerhard Joachim Schnaiter
  • Patent number: 8376649
    Abstract: A coupling device is provided for transmitting a torque between a drive element and a clutch, for example of a motor vehicle. The coupling device includes a first shaft and a second shaft being coupled together in a positive fit. The device is equipped with an elastic element which in the positive-fit connection generates a pre-tension to suppress rattling noises.
    Type: Grant
    Filed: October 15, 2006
    Date of Patent: February 19, 2013
    Assignee: BorgWarner Inc.
    Inventors: Johannes Heinrich, Michael Schäfer, Jochen Bölling, Dietmar Strauss, Till Ebner
  • Patent number: 8322503
    Abstract: The inventive double-clutch transmission element for a hybrid pull chain of a motor vehicle comprises a motion input shaft (37), a motion output shaft (39), an electrical machine (31) comprising a stator (61) and a rotor (63), a first clutch (33) providing a connection between the input shaft (37) and an intermediate member (73), and a second clutch (35) providing a connection between the intermediate member (73) and the output shaft (39), the intermediate member (73) being coupled in rotation to the rotor (63). A casing comprising a first half-shell (51) rotatably supporting the input shaft (37) and a second half-shell (52) rotatably supporting the output shaft (39) defines a housing in which the two clutches (33, 35) and the electrical machine (31) are mounted in a co-axial manner. The invention also relates to a motor vehicle equipped with such transmission element and to a method of mounting same.
    Type: Grant
    Filed: May 31, 2005
    Date of Patent: December 4, 2012
    Assignee: Peugeot Citroen Automobiles SA
    Inventors: Emmanuel Combes, Herve Focqueur, Johannes Heinrich, Hans Jurgen Hauck
  • Publication number: 20120107856
    Abstract: The present invention provides a new fungal production system comprising a fungal host strain of Chrysosporium lucknowense wherein the endogenous cellulase secretion is less than 20% of the endogenous cellulase secretion of Chrysosporium lucknowense strain UV 18-25. Preferably, also the secretion of endogenous protease, endogenous ?-glucanase and endogenous cellobiohydrolase is less than 20% of the secretion of Chrysosporium lucknowense strain UV 18-25. Furthermore, fungal host strains are provided wherein several genes have been disrupted. According to another aspect of the invention a method for homologous and/or heterologous production of a pure protein with a purity of higher than 75%, comprising expressing a gene encoding said protein in the strains according to the invention have been described. Furthermore, a method for production of artificial protein mixes comprising expressing a gene encoding each of said proteins in a strain according to the invention have been disclosed.
    Type: Application
    Filed: March 16, 2010
    Publication date: May 3, 2012
    Inventors: Peter J. Punt, Richard Paul Burlingame, Christine M. Pynnonen, Phillip T. Olson, Jan Wery, Johannes Heinrich Visser, Mark A. Emalfarb, Jacob Visser, Jan Cormelis Verdoes, Jacoba Verdoes
  • Publication number: 20120093773
    Abstract: Methods are described for the delivery of one or more small interfering RNAs (siRNAs) to a eukaryotic cell using a bacterium. Methods are also described for using this bacterium to regulate gene expression in eukaryotic cells using RNA interference, and methods for treating cancer of cell proliferative disorders. The bacterium includes one or more siRNAs or one or more DNA molecules encoding one or more siRNAs. Vectors are also described for use with the bacteria of the invention for causing RNA interference in eukaryotic cells.
    Type: Application
    Filed: August 2, 2011
    Publication date: April 19, 2012
    Inventors: Chiang Li, Johannes Heinrich Fruehauf, Shuanglin Xiang
  • Patent number: 8056691
    Abstract: The invention relates to a device for axially positioning a clutch device, especially a dual-clutch device, on a rotary drive, wherein the clutch device is mounted so as to rotate about a rotational axis of said rotary drive. A retaining nut is coaxially screwed with the rotary drive, and the clutch device is indirectly or directly supported on said nut in an axial direction.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: November 15, 2011
    Assignee: BorgWarner Inc.
    Inventors: Eckart Gold, Johannes Heinrich, Marcus Hertel, Martin Gerlach, Götz Nicklas, Hans-Jürgen Hauck, Jens Henze