Abstract: The present invention describes a fermentation process for the production of a desired compound (such as natamycin) comprising cultivating a filamentous bacterial strain in a liquid fermentation medium, wherein the carbon containing nutrients and nitrogen containing nutrients are maintained at low concentrations in the fermentation medium. The process of the invention reduces the viscosity of the culture medium and therefore increases the yield of the desired compound.

Abstract: The invention relates to a fluid suitable for use in haemofiltration, in particular for use in continuous veno-venous haemofiltration (CVVH). The fluid comprises an aqueous solution of physiologically acceptable salts containing at least Na+, Cl−, Mg2+, K+ and Ca2+ ions and optionally glucose, all in a physiologically acceptable concentration. The haemofiltration fluid is characterised in that the fluid contains the ions K+ in a concentration higher than 3 mmol/l and lower than 5.5 mmol/l and Ca2+ in a concentration lower than 1.5 mmol/l.