Patents by Inventor Johannes Huebner

Johannes Huebner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell wall polymers of and uses thereof
    Patent number: 9750796
    Abstract: The present invention relates to enterococcal cell wall polymers and their uses in the prevention and therapy of bacterial infection.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: September 5, 2017
    Assignees: UNIVERSITAETSKLINKUM FREIBURG, FORSCHUNGSZENTRUM BORSTEL
    Inventors: Johannes Huebner, Otto Holst, Christian Theilacker, Karolina Kruszynska, Stefan Geiss-Liebisch, Agnieszka Beczala
  • Synthetic LTA mimetics and use thereof as vaccine component for therapy and/or prophylaxis against gram-positive infections
    Patent number: 9290531
    Abstract: The present invention relates to synthetic lipoteicoic acid (LTA) mimetics which are useful as vaccine components for therapy and/or prophylaxis of bacterial infection.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: March 22, 2016
    Assignee: UNIVERSITÄTSKLINIKUM FREIBURG
    Inventors: Johannes Huebner, Andrea Huebner-Kropec, Jeroen Dirk Cornelis Codée, Gijsbert Arie Van Der Marel, Wouter Frederick Johan Hogendorf
  • NOVEL CELL WALL POLYMERS OF ENTEROCOCCUS FAECALIS AND USES THEREOF
    Publication number: 20150139998
    Abstract: The present invention relates to enterococcal cell wall polymers and their uses in the prevention and therapy of bacterial infection.
    Type: Application
    Filed: March 4, 2013
    Publication date: May 21, 2015
    Inventors: Johannes Huebner, Otto Holst, Christian Theilacker, Karolina Kruszynska, Stefan Geiss-Liebisch, Agnieszka Beczala
  • Polypeptide derived from and its use for vaccination
    Patent number: 8741302
    Abstract: A medicament for the treatment or the prevention of a bacterial infection is disclosed which contains a polypeptide having a contiguous sequence of at least six amino acids of SEQ ID NO:1. Said polypeptide can be used for the preparation of a vaccine against an Enterococcus infection.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: June 3, 2014
    Assignee: Universitatsklinikum Freiburg
    Inventors: Johannes Huebner, Andrea Kropec-Huebner, Irina Sava
  • SYNTHETIC LTA MIMETICS AND USE THEREOF AS VACCINE COMPONENT FOR THERAPY AND/OR PROPHYLAXIS AGAINST GRAM-POSITIVE INFECTIONS
    Publication number: 20140050741
    Abstract: The present invention relates to synthetic lipoteicoic acid (LTA) mimetics which are useful as vaccine components for therapy and/or prophylaxis of bacterial infection.
    Type: Application
    Filed: February 17, 2012
    Publication date: February 20, 2014
    Applicants: UNIVERSITEIT LEIDEN, UNIVERSITÄTSKLINIKUM FREIBURG
    Inventors: Johannes Huebner, Andrea Huebner-Kropec, Jeroen Dirk Cornelis Codée, Gijsbert Arie Van Der Marel, Wouter Frederick Johan Hogendorf
  • Polypeptide Derived From Enterococcus And Its Use For Vaccination
    Publication number: 20120121638
    Abstract: A medicament for the treatment or the prevention of a bacterial infection is disclosed which contains a polypeptide having a contiguous sequence of at least six amino acids of SEQ ID NO:1. Said polypeptide can be used for the preparation of a vaccine against an Enterococcus infection.
    Type: Application
    Filed: April 26, 2010
    Publication date: May 17, 2012
    Inventors: Johannes Huebner, Andrea Kropec-Huener, Irina Sava
  • Capsular polysaccharides from enterococci
    Patent number: 6722062
    Abstract: The present invention is directed to a method for purifying polysaccharides capable of inducing the production of high titers of opsonic antibodies that kill strains of enterococcal bacteria. In addition, the invention is directed to the antigens produced by this purification method and to vaccines which utilize such antigens.
    Type: Grant
    Filed: March 11, 2002
    Date of Patent: April 20, 2004
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Gerald B. Pier, Johannes Huebner, Ying Wang, Lawrence Madoff
  • Capsular polysaccharides from enterococci
    Publication number: 20020122809
    Abstract: The present invention is directed to a method for purifying polysaccharides capable of inducing the production of high titers of opsonic antibodies that kill strains of enterococcal bacteria. In addition, the invention is directed to the antigens produced by this purification method and to vaccines which utilize such antigens.
    Type: Application
    Filed: March 11, 2002
    Publication date: September 5, 2002
    Applicant: The Brigham and Women's Hospital, Inc.
    Inventors: Gerald B. Pier, Johannes Huebner, Ying Wang, Lawrence Madoff
  • Capsular polysaccharides from enterococci
    Patent number: 5989542
    Abstract: The present invention is directed to a method for purifying polysaccharides capable of inducing the production of high titers of opsonic antibodies that kill strains of enterococcal bacteria. In addition, the invention is directed to the antigens produced by this purification method and to vaccines which utilize such antigens.
    Type: Grant
    Filed: August 17, 1998
    Date of Patent: November 23, 1999
    Assignee: Brigham and Women's Hospital, Inc.
    Inventors: Gerald B. Pier, Johannes Huebner, Ying Wang, Lawrence Madoff