Patents by Inventor Johannes Irsch

Johannes Irsch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation and characterization of allergen-binding cells for diagnosis of hypersensitivity
    Patent number: 5916818
    Abstract: Methods and compositions are provided for the diagnosis of allergen hypersensitivity in a patient. Rare, allergen-specific cells are enriched from a complex cell population, e.g. a patient blood sample. The percentage of blood cells that bind to a particular allergen is less than 0.01%. The allergen-specific cell population is enriched by magnetic cell sorting. In normal blood, the allergen-binding cells are primarily B-cells expressing CD19 and CD21. In blood from allergic patients, an additional population of effector cells, e.g. basophilic granulocytes is labeled by the allergen.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: June 29, 1999
    Assignee: Miltenyi Biotec GmbH
    Inventors: Johannes Irsch, Stefan Miltenyi, Andreas Radbruch
  • Isolation and characterization of allergen-binding cells for diagnosis of hypersensitivity
    Patent number: 5786161
    Abstract: Methods and compositions are provided for the diagnosis of allergen hypersensitivity in a patient. Rare, allergen-specific cells are enriched from a complex cell population, e.g. a patient blood sample. The percentage of blood cells that bind to a particular allergen is less than 0.01%. The allergen-specific cell population is enriched by magnetic cell sorting. In normal blood, the allergen-binding cells are primarily B-cells expressing CD19 and CD21. In blood from allergic patients, an additional population of effector cells, e.g. basophilic granulocytes is labeled by the allergen.
    Type: Grant
    Filed: June 6, 1996
    Date of Patent: July 28, 1998
    Assignee: Miltenyi Biotec. GmbH
    Inventors: Johannes Irsch, Stefan Miltenyi, Andreas Radbruch