Patents by Inventor Johannes L. Zakrzewski

Johannes L. Zakrzewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR OFF-THE-SHELF-TUMOR IMMUNOTHERAPY USING ALLOGENEIC T-CELL PRECURSORS
    Publication number: 20190307800
    Abstract: The inventive subject matter relates to methods for treating a T-cell deficiency in a subject in need thereof, comprising administering to said subject a T-cell precursor isolated from an allogeneic donor, provided that said allogeneic donor is not MHC-matched to said subject. The inventive methods can be further enhanced by genetic engineering for targeted immunotherapy.
    Type: Application
    Filed: May 22, 2019
    Publication date: October 10, 2019
    Applicant: MEMORIAL SLOAN KETTERING CANCER CENTER
    Inventors: Johannes L. Zakrzewski, Marcel R.m. Van Den Brink, Michel Sadelain
  • Methods for off-the-shelf-tumor immunotherapy using allogeneic T-cell precursors
    Patent number: 10350243
    Abstract: The inventive subject matter relates to methods for treating a T-cell deficiency in a subject in need thereof, comprising administering to said subject a T-cell precursor isolated from an allogeneic donor, provided that said allogeneic donor is not MHC-matched to said subject. The inventive methods can be further enhanced by genetic engineering for targeted immunotherapy.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: July 16, 2019
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Johannes L. Zakrzewski, Marcel R. m. Van Den Brink, Michel Sadelain
  • Methods for off-the-shelf tumor immunotherapy using allogeneic T-cell precursors
    Patent number: 10059923
    Abstract: The inventive subject matter relates to methods for treating a T-cell deficiency in a subject in need thereof, comprising administering to said subject a T-cell precursor isolated from an allogeneic donor, provided that said allogeneic donor is not MHC-matched to said subject. The inventive methods can be further enhanced by genetic engineering for targeted immunotherapy.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: August 28, 2018
    Assignee: MEMORIAL SLOAN KETTERING CANCER CENTER
    Inventors: Johannes L. Zakrzewski, Marcel R. M. Van Den Brink, Michel Sadelain
  • METHODS FOR OFF-THE-SHELF-TUMOR IMMUNOTHERAPY USING ALLOGENEIC T-CELL PRECURSORS
    Publication number: 20170049818
    Abstract: The inventive subject matter relates to methods for treating a T-cell deficiency in a subject in need thereof, comprising administering to said subject a T-cell precursor isolated from an allogeneic donor, provided that said allogeneic donor is not MHC-matched to said subject. The inventive methods can be further enhanced by genetic engineering for targeted immunotherapy.
    Type: Application
    Filed: February 19, 2016
    Publication date: February 23, 2017
    Applicant: Memorial Sloan-Kettering Cancer Center
    Inventors: Johannes L. Zakrzewski, Marcel R.m. Van Den Brink, Michel Sadelain
  • METHODS FOR OFF-THE- SHELF TUMOR IMMUNOTHERAPY USING ALLOGENEIC T-CELL PRECURSORS
    Publication number: 20110052554
    Abstract: The inventive subject matter relates to methods for treating a T-cell deficiency in a subject in need thereof, comprising administering to said subject a T-cell precursor isolated from an allogeneic donor, provided that said allogeneic donor is not MHC-matched to said subject. The inventive methods can be further enhanced by genetic engineering for targeted immunotherapy.
    Type: Application
    Filed: January 30, 2009
    Publication date: March 3, 2011
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Johannes L. Zakrzewski, Marcel R.m. Van Der Brink, Michael Sadelain