Patents by Inventor Johannes Leierer

Johannes Leierer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mucoadhesive polymers having vitamin B partial structures
    Patent number: 10639377
    Abstract: Because of the formation of disulfide bridges with mucus glycoproteins, the mucoadhesive properties of polymeric compounds can be significantly improved by the covalent attachment of thiol substructures to them. By the transformation of free thiol groups on such polymers in disulfides with mercaptonicotinamides or mercaptopyridoxins these thiol groups become comparatively more reactive resulting in significantly improved mucoadhesive properties. Furthermore, polymers exhibiting disulfide partial structures with mercaptonicotinamides or mercaptopyridoxins do not need to be protected against oxidation. In addition, they show comparatively higher permeation enhancing properties.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: May 5, 2020
    Assignees: THIOMATRIX FORSCHUNGS-UND BERATUNGS GMBH, CROMA PHARMA GMBH
    Inventor: Johannes Leierer
  • MUCOADHESIVE POLYMERS HAVING VITAMIN B PARTIAL STRUCTURES
    Publication number: 20150209434
    Abstract: Because of the formation of disulfide bridges with mucus glycoproteins, the mucoadhesive properties of polymeric compounds can be significantly improved by the covalent attachment of thiol substructures to them. By the transformation of free thiol groups on such polymers in disulfides with mercaptonicotinamides or mercaptopyridoxins these thiol groups become comparatively more reactive resulting in significantly improved mucoadhesive properties. Furthermore, polymers exhibiting disulfide partial structures with mercaptonicotinamides or mercaptopyridoxins do not need to be protected against oxidation. In addition, they show comparatively higher permeation enhancing properties.
    Type: Application
    Filed: February 12, 2015
    Publication date: July 30, 2015
    Inventor: Johannes Leierer
  • Mucoadhesive polymers having vitamin B partial structures
    Patent number: 8980238
    Abstract: Because of the formation of disulfide bridges with mucus glycoproteins, the mucoadhesive properties of polymeric compounds can be significantly improved by the covalent attachment of thiol substructures to them. By the transformation of free thiol groups on such polymers in disulfides with mercaptonicotinamides or mercaptopyridoxins these thiol groups become comparatively more reactive resulting in significantly improved mucoadhesive properties. Furthermore, polymers exhibiting disulfide partial structures with mercaptonicotinamides or mercaptopyridoxins do not need to be protected against oxidation. In addition, they show comparatively higher permeation enhancing properties.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: March 17, 2015
    Assignees: Thiomatrix Forschungs—Und Beratungs GmbH, Croma Pharma GmbH
    Inventor: Johannes Leierer
  • MUCOADHESIVE POLYMERS HAVING VITAMIN B PARTIAL STRUCTURES
    Publication number: 20120225024
    Abstract: Because of the formation of disulfide bridges with mucus glycoproteins, the mucoadhesive properties of polymeric compounds can be significantly improved by the covalent attachment of thiol substructures to them. By the transformation of free thiol groups on such polymers in disulfides with mercaptonicotinamides or mercaptopyridoxins these thiol groups become comparatively more reactive resulting in significantly improved mucoadhesive properties. Furthermore, polymers exhibiting disulfide partialstructures with mercaptonicotinamides or mercaptopyridoxins do not need to be protected against oxidation. In addition, they show comparatively higher permeation enhancing properties.
    Type: Application
    Filed: September 29, 2010
    Publication date: September 6, 2012
    Applicant: YKK cORPORATION
    Inventor: Johannes Leierer