Patents by Inventor Johannes P. Van Dijken

Johannes P. Van Dijken has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microorganisms engineered to use unconventional sources of phosphorous or sulfur
    Patent number: 11535829
    Abstract: Disclosed are genetically engineered organisms, such as yeast and bacteria, that have the ability to metabolize atypical phosphorus or sulfur sources. Fermentation methods using the genetically engineered organisms are also described. The fermentation methods are robust processes for the industrial bioproduction of a variety of compounds, including commodities, fine chemicals, an pharmaceuticals.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: December 27, 2022
    Assignee: Ginkgo Bioworks, Inc.
    Inventors: Arthur J. Shaw, IV, Colin R. South, Johannes P. Van Dijken
  • Engineering an increase in ethanol production by altering cofactor specificity
    Patent number: 10767196
    Abstract: The present invention provides for the manipulation of cofactor usage in a recombinant host cell to increase the formation of desirable products. In some embodiments, the invention provides for a recombinant microorganism comprising a mutation in one or more native enzymes such that their cofactor specificity is altered in such a way that overall cofactor usage in the cell is balanced for a specified pathway and there is an increase in a specific product formation within the cell. In some embodiments, endogenous enzymes are replaced by enzymes with an alternate cofactor specificity from a different species.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: September 8, 2020
    Assignees: Enchi Corporation, Dartmouth College, UT-Battelle, LLC
    Inventors: Jonathan Lo, Adam M. Guss, Johannes P. Van Dijken, Arthur J. Shaw, IV, Daniel G. Olson, Christopher D. Herring, D. Aaron Argyros, Nicky Caiazza
  • Increasing lipid production and optimizing lipid composition
    Patent number: 10724041
    Abstract: Disclosed are nucleotide sequences and corresponding amino acid sequences of Arxula adeninivorans genes that can be utilized to manipulate the lipid content and/or composition of a cell. Methods and compositions for utilizing this information are disclosed to increase the lipid content or modify the lipid composition of a cell by either increasing or decreasing the activity of certain genetic targets.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: July 28, 2020
    Assignee: NOVOGY, INC.
    Inventors: Elena E. Brevnova, Arthur J. Shaw, IV, Johannes P. Van Dijken
  • Microorganisms Engineered to Use Unconventional Sources of Phosphorous or Sulfur
    Publication number: 20190233800
    Abstract: Disclosed are genetically engineered organisms, such as yeast and bacteria, that have the ability to metabolize atypical phosphorus or sulfur sources. Fermentation methods using the genetically engineered organisms are also described. The fermentation methods are robust processes for the industrial bioproduction of a variety of compounds, including commodities, fine chemicals, and pharmaceuticals.
    Type: Application
    Filed: November 27, 2018
    Publication date: August 1, 2019
    Inventors: Arthur J Shaw, IV, Colin R South, Johannes P Van Dijken
  • Microorganisms engineered to use unconventional sources of phosphorous or sulfur
    Patent number: 10174296
    Abstract: Disclosed are genetically engineered organisms, such as yeast and bacteria, that have the ability to metabolize atypical phosphorus or sulfur sources. Fermentation methods using the genetically engineered organisms are also described. The fermentation methods are robust processes for the industrial bioproduction of a variety of compounds, including commodities, fine chemicals, and pharmaceuticals.
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: January 8, 2019
    Assignee: Novogy, Inc.
    Inventors: Arthur J. Shaw, IV, Colin R. South, Johannes P. Van Dijken
  • MICROORGANISMS ENGINEERED TO USE UNCONVENTIONAL SOURCES OF PHOSPHOROUS OR SULFUR
    Publication number: 20160215274
    Abstract: Disclosed are genetically engineered organisms, such as yeast and bacteria, that have the ability to metabolize atypical phosphorus or sulfur sources. Fermentation methods using the genetically engineered organisms are also described. The fermentation methods are robust processes for the industrial bioproduction of a variety of compounds, including commodities, fine chemicals, and pharmaceuticals.
    Type: Application
    Filed: August 27, 2014
    Publication date: July 28, 2016
    Inventors: Arthur J. Shaw, Colin R. South, Johannes P. Van Dijken
  • Engineering an Increase in Ethanol Production by Altering Cofactor Specificity
    Publication number: 20140322783
    Abstract: The present invention provides for the manipulation of cofactor usage in a recombinant host cell to increase the formation of desirable products. In some embodiments, the invention provides for a recombinant microorganism comprising a mutation in one or more native enzymes such that their cofactor specificity is altered in such a way that overall cofactor usage in the cell is balanced for a specified pathway and there is an increase in a specific product formation within the cell. In some embodiments, endogenous enzymes are replaced by enzymes with an alternate cofactor specificity from a different species.
    Type: Application
    Filed: November 30, 2012
    Publication date: October 30, 2014
    Inventors: Jonathan Lo, Adam M. Guss, Johannes P. Van Dijken, Arthur J. Shaw, IV, Daniel G. Olson, Christopher D. Herring