Patents by Inventor Johannes Schmitz

Johannes Schmitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11624057
    Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.
    Type: Grant
    Filed: March 17, 2021
    Date of Patent: April 11, 2023
    Assignee: DSM IP ASSETS B.V.
    Inventors: Paulus Petrus De Waal, Ingrid Maria Vugt-Van Lutz, Jozef Petrus Johannes Schmitz, Hans Marinus Charles Johannes De Bruijn
  • Publication number: 20220325253
    Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.
    Type: Application
    Filed: March 17, 2021
    Publication date: October 13, 2022
    Inventors: Paulus Petrus DE WAAL, Ingrid Maria VUGT - VAN LUTZ, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
  • Publication number: 20220204947
    Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.
    Type: Application
    Filed: March 17, 2021
    Publication date: June 30, 2022
    Inventors: Paulus Petrus DE WAAL, Ingrid Maria VUGT - VAN LUTZ, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
  • Patent number: 11319543
    Abstract: The present invention relates to a yeast cell that is genetically modified comprising: a) a disruption of one or more aldehyde dehydrogenase (E.C:1.2.1.4) native to the yeast; b) one or more nucleotide sequence encoding a heterologous NAD+-dependent acetylating acetaldehyde dehydrogenase (E.C. 1.2.1.10); c) one or more nucleotide sequence encoding a homologous or heterologous acetyl-CoA synthetase (E.C. 6.2.1.1); and d) a modification that leads to reduction of glycerol 3-phosphate phosphohydrolase (E.C. 3.1.3.21) and/or glycerol 3-phosphate dehydrogenase (E.C. 1.1.1.8 or E.C. 1.1.5.3) activity, native to the yeast.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: May 3, 2022
    Assignee: DSM IP ASSETS B.V.
    Inventors: Paul Klaassen, Jozef Petrus Johannes Schmitz, Paulus Petrus De Waal, Arjen Bouma
  • Patent number: 11203741
    Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter, wherein the recombinant yeast comprises overexpression of one or more PPP-genes. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.
    Type: Grant
    Filed: June 11, 2021
    Date of Patent: December 21, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Paulus Petrus De Waal, Ingrid Maria Vugt-Van Lutz, Jozef Petrus Johannes Schmitz, Hans Marinus Charles Johannes De Bruijn
  • Patent number: 11186850
    Abstract: The present invention describes a recombinant yeast cell functionally expressing one or more heterologous nucleic acid sequences encoding for ribulose-1,5-phosphate carboxylase/oxygenase (EC4.1.1.39; Rubisco), and optionally one or more molecular chaperones for Rubisco, and one or more phosphoribulokinase (EC2.7.1.19; PRK), wherein the phosphoribulokinase is under control of a promoter (the “PRK promoter”) that enables higher expression under anaerobic conditions than under aerobic conditions.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: November 30, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Ioannis Papapetridis, Antonius Jeroen Adriaan Van Maris, Jacobus Thomas Pronk, Paulus Petrus De Waal, Niels Lauret, Maarten Dirk Verhoeven, Jozef Petrus Johannes Schmitz
  • Publication number: 20210317420
    Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter, wherein the recombinant yeast comprises overexpression of one or more PPP-genes. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.
    Type: Application
    Filed: June 11, 2021
    Publication date: October 14, 2021
    Inventors: Paulus Petrus DE WAAL, Ingrid Maria VUGT - VAN LUTZ, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
  • Publication number: 20210310013
    Abstract: The present invention relates to a yeast cell that is genetically modified comprising: a) a disruption of one or more aldehyde dehydrogenase (E.C: 1.2.1.4) native to the yeast; b) one or more nucleotide sequence encoding a heterologous NAD+-dependent acetylating acetaldehyde dehydrogenase (E.C. 1.2.1.10); c) one or more nucleotide sequence encoding a homologous or heterologous acetyl-CoA synthetase (E.C. 6.2.1.1); and d) a modification that leads to reduction of glycerol 3-phosphate phosphohydrolase (E.C. 3.1.3.21) and/or glycerol 3-phosphate dehydrogenase (E.C. 1.1.1.8 or E.C. 1.1.5.3) activity, native to the yeast.
    Type: Application
    Filed: June 14, 2021
    Publication date: October 7, 2021
    Inventors: PAUL KLAASSEN, JOZEF PETRUS JOHANNES SCHMITZ, PAULUS PETRUS DE WAAL, ARJEN BOUMA
  • Patent number: 10982195
    Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: April 20, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Paulus Petrus De Waal, Ingrid Maria Vugt-Van Lutz, Jozef Petrus Johannes Schmitz, Hans Marinus Charles Johannes De Bruijn
  • Publication number: 20200347422
    Abstract: The invention relates to a process for the preparation of a sugar and/or fermentation product from lignocellulosic material.
    Type: Application
    Filed: October 29, 2018
    Publication date: November 5, 2020
    Inventors: Maaike APPELDOORN, Jozef Petrus Johannes SCHMITZ, Bertus NOORDAM
  • Publication number: 20200283805
    Abstract: The invention relates to a process for the production of ethanol from a composition comprising at least glucose comprising fermenting said composition in the presence of a recombinant yeast; and recovering the ethanol, wherein said yeast comprises one or more genes coding for an enzyme having glycerol dehydrogenase activity, one or more genes coding for an enzyme having dihydroxyacetone kinase activity (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); one or more genes coding for an enzyme in an acetyl-CoA-production pathway and one or more genes coding for an enzyme having at least NAD+ dependent acetylating acetaldehyde dehydrogenase activity (EC 1.2.1.10 or EC 1.1.1.2), and optionally one or more genes coding for a glycerol transporter, wherein the composition comprises an amount of undissociated acetic acid of 10 mM or less.
    Type: Application
    Filed: September 25, 2018
    Publication date: September 10, 2020
    Inventors: Paulus Petrus DE WAAL, Ingrid Maria VUGT - VAN LUTZ, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
  • Patent number: 10745840
    Abstract: A device for the treatment of strand-shaped textiles includes a treatment container, a transport nozzle array, and a transport path by way of which a material strand can be moved through the transport nozzle array in a transport direction. The transport nozzle array includes a transport nozzle with nozzle inlet and outlet orifices for the material strand, between which are delimited at least two nozzle gaps for a transport medium. At least one of the nozzle gaps is adjustable regarding its gap width. At least one nozzle gap can convey the material strand in the transport direction, and at least one nozzle gap can convey the material strand in a direction counter to the transport direction. The device also includes a control unit that selectively drives the material strand in the transport direction or in the direction counter to the transport direction by appropriate actuation of the nozzle gaps.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: August 18, 2020
    Assignee: FONG'S EUROPE GMBH
    Inventor: Johannes Schmitz
  • Publication number: 20200255871
    Abstract: The present invention describes a recombinant yeast cell functionally expressing one or more heterologous nucleic acid sequences encoding for ribulose-1,5-phosphate carboxylase/oxygenase (EC4.1.1.39; Rubisco), and optionally one or more molecular chaperones for Rubisco, and one or more phosphoribulokinase (EC2.7.1.19; PRK), wherein the phosphoribulokinase is under control of a promoter (the “PRK promoter”) that enables higher expression under anaerobic conditions than under aerobic conditions.
    Type: Application
    Filed: April 24, 2020
    Publication date: August 13, 2020
    Inventors: Ioannis PAPAPETRIDIS, Antonius Jeroen Adriaan VAN MARIS, Jacobus Thomas PRONK, Paulus Petrus DE WAAL, Niels LAURET, Maarten Dirk VERHOEVEN, Jozef Petrus Johannes SCHMITZ
  • Patent number: 10689670
    Abstract: The present invention describes a recombinant yeast cell functionally expressing one or more heterologous nucleic acid sequences encoding for ribulose-1,5-phosphate carboxylase/oxygenase (EC4.1.1.39; Rubisco), and optionally one or more molecular chaperones for Rubisco, and one or more phosphoribulokinase (EC2.7.1.19; PRK), wherein the phosphoribulokinase is under control of a promoter (the “PRK promoter”) that enables higher expression under anaerobic conditions than under aerobic conditions.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: June 23, 2020
    Assignee: DSM IP ASSETS B.V.
    Inventors: Ioannis Papapetridis, Antonius Jeroen Adriaan Van Maris, Jacobus Thomas Pronk, Paulus Petrus De Waal, Niels Lauret, Maarten Dirk Verhoeven, Jozef Petrus Johannes Schmitz
  • Publication number: 20200024619
    Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising one or more genes coding for an enzyme having glycerol dehydrogenase activity, one or more genes coding dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); one or more genes coding for an enzyme in an acetyl-CoA-production pathway and one or more genes coding for an enzyme having at least NAD+ dependent acetylating acetaldehyde dehydrogenase activity (EC 1.2.1.10 or EC 1.1.1.2), and optionally one or more genes coding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.
    Type: Application
    Filed: March 20, 2018
    Publication date: January 23, 2020
    Inventors: Paulus Petrus DE WAAL, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
  • Publication number: 20190309268
    Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.
    Type: Application
    Filed: December 18, 2017
    Publication date: October 10, 2019
    Inventors: Paulus Petrus DE WAAL, Ingrid Maria VUGT - VAN LUTZ, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
  • Publication number: 20190249201
    Abstract: The present invention describes a recombinant yeast cell functionally expressing one or more heterologous nucleic acid sequences encoding for ribulose-1,5-phosphate carboxylase/oxygenase (EC4.1.1.39; Rubisco), and optionally one or more molecular chaperones for Rubisco, and one or more phosphoribulokinase (EC2.7.1.19; PRK), wherein the phosphoribulokinase is under control of a promoter (the “PRK promoter”) that enables higher expression under anaerobic conditions than under aerobic conditions.
    Type: Application
    Filed: June 13, 2017
    Publication date: August 15, 2019
    Inventors: Ioannis PAPAPETRIDIS, Antonius Jeroen Adriaan VAN MARIS, Jacobus Thomas PRONK, Paulus Petrus DE WAAL, Niels LAURET, Maarten Dirk VERHOEVEN, Jozef Petrus Johannes SCHMITZ
  • Publication number: 20180334768
    Abstract: A device for the treatment of strand-shaped textiles includes a treatment container, a transport nozzle array, and a transport path by way of which a material strand can be moved through the transport nozzle array in a transport direction. The transport nozzle array includes a transport nozzle with nozzle inlet and outlet orifices for the material strand, between which are delimited at least two nozzle gaps for a transport medium. At least one of the nozzle gaps is adjustable regarding its gap width. At least one nozzle gap can convey the material strand in the transport direction, and at least one nozzle gap can convey the material strand in a direction counter to the transport direction. The device also includes a control unit that selectively drives the material strand in the transport direction or in the direction counter to the transport direction by appropriate actuation of the nozzle gaps.
    Type: Application
    Filed: August 11, 2016
    Publication date: November 22, 2018
    Applicant: FONG'S EUROPE GMBH
    Inventor: Johannes SCHMITZ
  • Patent number: 10000873
    Abstract: An apparatus for treatment of a strand-like textile material in the form of a continuous material rope, which is circulated during at least part of the treatment, includes: an elongated, essentially tubular treatment container; a transport nozzle array to which a transport medium flow can be applied; and a transport section adjoining the transport nozzle array. The transport section terminates on a material rope inlet side in a storage section of the treatment container. The storage section accommodates a folded material rope pile and includes: a gliding bottom extending at a distance above a container wall below, the gliding bottom extending from the material rope inlet side of the storage section to a material rope outlet side in vicinity of the transport nozzle array; and at least one unit provided for changing an inclination of the gliding bottom from the material rope inlet side toward the material rope outlet side.
    Type: Grant
    Filed: September 20, 2014
    Date of Patent: June 19, 2018
    Assignee: FONG'S EUROPE GMBH
    Inventor: Johannes Schmitz
  • Patent number: 9982378
    Abstract: A device for treatment of a strand-like textile fabric in the form of an endless fabric strand, includes: a lockable treatment container; a transport nozzle arrangement which can be subjected to a first transport medium flow; and a transport section adjoining the transport nozzle arrangement. The transport section terminates on a fabric strand inlet side in a storage section of the lockable treatment container, and the storage section accommodates a folded fabric strand pile. The transport nozzle arrangement includes a transport nozzle with a polygonal nozzle inlet opening and an outlet part having a polygonal cross-section, for the fabric strand. The outlet part is appropriately adapted in view of its dimensions. The nozzle gap is adjustable and is delimited all the way around on at least one side by a plurality of straight nozzle elements that each have a cross-sectional shape that is essentially part-cylindrical.
    Type: Grant
    Filed: September 20, 2014
    Date of Patent: May 29, 2018
    Assignee: FONG'S EUROPE GMBH
    Inventor: Johannes Schmitz