Patents by Inventor Johannes Schmitz
Johannes Schmitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11624057Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.Type: GrantFiled: March 17, 2021Date of Patent: April 11, 2023Assignee: DSM IP ASSETS B.V.Inventors: Paulus Petrus De Waal, Ingrid Maria Vugt-Van Lutz, Jozef Petrus Johannes Schmitz, Hans Marinus Charles Johannes De Bruijn
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Publication number: 20220325253Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.Type: ApplicationFiled: March 17, 2021Publication date: October 13, 2022Inventors: Paulus Petrus DE WAAL, Ingrid Maria VUGT - VAN LUTZ, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
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Publication number: 20220204947Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.Type: ApplicationFiled: March 17, 2021Publication date: June 30, 2022Inventors: Paulus Petrus DE WAAL, Ingrid Maria VUGT - VAN LUTZ, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
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Patent number: 11319543Abstract: The present invention relates to a yeast cell that is genetically modified comprising: a) a disruption of one or more aldehyde dehydrogenase (E.C:1.2.1.4) native to the yeast; b) one or more nucleotide sequence encoding a heterologous NAD+-dependent acetylating acetaldehyde dehydrogenase (E.C. 1.2.1.10); c) one or more nucleotide sequence encoding a homologous or heterologous acetyl-CoA synthetase (E.C. 6.2.1.1); and d) a modification that leads to reduction of glycerol 3-phosphate phosphohydrolase (E.C. 3.1.3.21) and/or glycerol 3-phosphate dehydrogenase (E.C. 1.1.1.8 or E.C. 1.1.5.3) activity, native to the yeast.Type: GrantFiled: May 18, 2016Date of Patent: May 3, 2022Assignee: DSM IP ASSETS B.V.Inventors: Paul Klaassen, Jozef Petrus Johannes Schmitz, Paulus Petrus De Waal, Arjen Bouma
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Patent number: 11203741Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter, wherein the recombinant yeast comprises overexpression of one or more PPP-genes. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.Type: GrantFiled: June 11, 2021Date of Patent: December 21, 2021Assignee: DSM IP ASSETS B.V.Inventors: Paulus Petrus De Waal, Ingrid Maria Vugt-Van Lutz, Jozef Petrus Johannes Schmitz, Hans Marinus Charles Johannes De Bruijn
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Patent number: 11186850Abstract: The present invention describes a recombinant yeast cell functionally expressing one or more heterologous nucleic acid sequences encoding for ribulose-1,5-phosphate carboxylase/oxygenase (EC4.1.1.39; Rubisco), and optionally one or more molecular chaperones for Rubisco, and one or more phosphoribulokinase (EC2.7.1.19; PRK), wherein the phosphoribulokinase is under control of a promoter (the “PRK promoter”) that enables higher expression under anaerobic conditions than under aerobic conditions.Type: GrantFiled: April 24, 2020Date of Patent: November 30, 2021Assignee: DSM IP ASSETS B.V.Inventors: Ioannis Papapetridis, Antonius Jeroen Adriaan Van Maris, Jacobus Thomas Pronk, Paulus Petrus De Waal, Niels Lauret, Maarten Dirk Verhoeven, Jozef Petrus Johannes Schmitz
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Publication number: 20210317420Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter, wherein the recombinant yeast comprises overexpression of one or more PPP-genes. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.Type: ApplicationFiled: June 11, 2021Publication date: October 14, 2021Inventors: Paulus Petrus DE WAAL, Ingrid Maria VUGT - VAN LUTZ, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
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Publication number: 20210310013Abstract: The present invention relates to a yeast cell that is genetically modified comprising: a) a disruption of one or more aldehyde dehydrogenase (E.C: 1.2.1.4) native to the yeast; b) one or more nucleotide sequence encoding a heterologous NAD+-dependent acetylating acetaldehyde dehydrogenase (E.C. 1.2.1.10); c) one or more nucleotide sequence encoding a homologous or heterologous acetyl-CoA synthetase (E.C. 6.2.1.1); and d) a modification that leads to reduction of glycerol 3-phosphate phosphohydrolase (E.C. 3.1.3.21) and/or glycerol 3-phosphate dehydrogenase (E.C. 1.1.1.8 or E.C. 1.1.5.3) activity, native to the yeast.Type: ApplicationFiled: June 14, 2021Publication date: October 7, 2021Inventors: PAUL KLAASSEN, JOZEF PETRUS JOHANNES SCHMITZ, PAULUS PETRUS DE WAAL, ARJEN BOUMA
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Patent number: 10982195Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.Type: GrantFiled: December 18, 2017Date of Patent: April 20, 2021Assignee: DSM IP ASSETS B.V.Inventors: Paulus Petrus De Waal, Ingrid Maria Vugt-Van Lutz, Jozef Petrus Johannes Schmitz, Hans Marinus Charles Johannes De Bruijn
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Publication number: 20200347422Abstract: The invention relates to a process for the preparation of a sugar and/or fermentation product from lignocellulosic material.Type: ApplicationFiled: October 29, 2018Publication date: November 5, 2020Inventors: Maaike APPELDOORN, Jozef Petrus Johannes SCHMITZ, Bertus NOORDAM
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Publication number: 20200283805Abstract: The invention relates to a process for the production of ethanol from a composition comprising at least glucose comprising fermenting said composition in the presence of a recombinant yeast; and recovering the ethanol, wherein said yeast comprises one or more genes coding for an enzyme having glycerol dehydrogenase activity, one or more genes coding for an enzyme having dihydroxyacetone kinase activity (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); one or more genes coding for an enzyme in an acetyl-CoA-production pathway and one or more genes coding for an enzyme having at least NAD+ dependent acetylating acetaldehyde dehydrogenase activity (EC 1.2.1.10 or EC 1.1.1.2), and optionally one or more genes coding for a glycerol transporter, wherein the composition comprises an amount of undissociated acetic acid of 10 mM or less.Type: ApplicationFiled: September 25, 2018Publication date: September 10, 2020Inventors: Paulus Petrus DE WAAL, Ingrid Maria VUGT - VAN LUTZ, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
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Patent number: 10745840Abstract: A device for the treatment of strand-shaped textiles includes a treatment container, a transport nozzle array, and a transport path by way of which a material strand can be moved through the transport nozzle array in a transport direction. The transport nozzle array includes a transport nozzle with nozzle inlet and outlet orifices for the material strand, between which are delimited at least two nozzle gaps for a transport medium. At least one of the nozzle gaps is adjustable regarding its gap width. At least one nozzle gap can convey the material strand in the transport direction, and at least one nozzle gap can convey the material strand in a direction counter to the transport direction. The device also includes a control unit that selectively drives the material strand in the transport direction or in the direction counter to the transport direction by appropriate actuation of the nozzle gaps.Type: GrantFiled: August 11, 2016Date of Patent: August 18, 2020Assignee: FONG'S EUROPE GMBHInventor: Johannes Schmitz
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Publication number: 20200255871Abstract: The present invention describes a recombinant yeast cell functionally expressing one or more heterologous nucleic acid sequences encoding for ribulose-1,5-phosphate carboxylase/oxygenase (EC4.1.1.39; Rubisco), and optionally one or more molecular chaperones for Rubisco, and one or more phosphoribulokinase (EC2.7.1.19; PRK), wherein the phosphoribulokinase is under control of a promoter (the “PRK promoter”) that enables higher expression under anaerobic conditions than under aerobic conditions.Type: ApplicationFiled: April 24, 2020Publication date: August 13, 2020Inventors: Ioannis PAPAPETRIDIS, Antonius Jeroen Adriaan VAN MARIS, Jacobus Thomas PRONK, Paulus Petrus DE WAAL, Niels LAURET, Maarten Dirk VERHOEVEN, Jozef Petrus Johannes SCHMITZ
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Patent number: 10689670Abstract: The present invention describes a recombinant yeast cell functionally expressing one or more heterologous nucleic acid sequences encoding for ribulose-1,5-phosphate carboxylase/oxygenase (EC4.1.1.39; Rubisco), and optionally one or more molecular chaperones for Rubisco, and one or more phosphoribulokinase (EC2.7.1.19; PRK), wherein the phosphoribulokinase is under control of a promoter (the “PRK promoter”) that enables higher expression under anaerobic conditions than under aerobic conditions.Type: GrantFiled: June 13, 2017Date of Patent: June 23, 2020Assignee: DSM IP ASSETS B.V.Inventors: Ioannis Papapetridis, Antonius Jeroen Adriaan Van Maris, Jacobus Thomas Pronk, Paulus Petrus De Waal, Niels Lauret, Maarten Dirk Verhoeven, Jozef Petrus Johannes Schmitz
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Publication number: 20200024619Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising one or more genes coding for an enzyme having glycerol dehydrogenase activity, one or more genes coding dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); one or more genes coding for an enzyme in an acetyl-CoA-production pathway and one or more genes coding for an enzyme having at least NAD+ dependent acetylating acetaldehyde dehydrogenase activity (EC 1.2.1.10 or EC 1.1.1.2), and optionally one or more genes coding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.Type: ApplicationFiled: March 20, 2018Publication date: January 23, 2020Inventors: Paulus Petrus DE WAAL, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
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Publication number: 20190309268Abstract: The invention relates to a recombinant cell, preferably a yeast cell comprising: a) one or more heterologous genes encoding a glycerol dehydrogenase activity; b) one or more genes encoding a dihydroxyacetone kinase (E.C. 2.7.1.28 and/or E.C. 2.7.1.29); c) one or more heterologous genes encoding a ribulose-1,5-biphosphate carboxylase oxygenase (EC 4.1.1.39, RuBisCO); and d) one or more heterologous genes encoding a phosphoribulokinase (EC 2.7.1.19, PRK); and optionally e) one or more heterologous genes encoding for a glycerol transporter. This cell can be used for the production of ethanol and advantageously produces little or no glycerol.Type: ApplicationFiled: December 18, 2017Publication date: October 10, 2019Inventors: Paulus Petrus DE WAAL, Ingrid Maria VUGT - VAN LUTZ, Jozef Petrus Johannes SCHMITZ, Hans Marinus Charles Johannes DE BRUIJN
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Publication number: 20190249201Abstract: The present invention describes a recombinant yeast cell functionally expressing one or more heterologous nucleic acid sequences encoding for ribulose-1,5-phosphate carboxylase/oxygenase (EC4.1.1.39; Rubisco), and optionally one or more molecular chaperones for Rubisco, and one or more phosphoribulokinase (EC2.7.1.19; PRK), wherein the phosphoribulokinase is under control of a promoter (the “PRK promoter”) that enables higher expression under anaerobic conditions than under aerobic conditions.Type: ApplicationFiled: June 13, 2017Publication date: August 15, 2019Inventors: Ioannis PAPAPETRIDIS, Antonius Jeroen Adriaan VAN MARIS, Jacobus Thomas PRONK, Paulus Petrus DE WAAL, Niels LAURET, Maarten Dirk VERHOEVEN, Jozef Petrus Johannes SCHMITZ
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Publication number: 20180334768Abstract: A device for the treatment of strand-shaped textiles includes a treatment container, a transport nozzle array, and a transport path by way of which a material strand can be moved through the transport nozzle array in a transport direction. The transport nozzle array includes a transport nozzle with nozzle inlet and outlet orifices for the material strand, between which are delimited at least two nozzle gaps for a transport medium. At least one of the nozzle gaps is adjustable regarding its gap width. At least one nozzle gap can convey the material strand in the transport direction, and at least one nozzle gap can convey the material strand in a direction counter to the transport direction. The device also includes a control unit that selectively drives the material strand in the transport direction or in the direction counter to the transport direction by appropriate actuation of the nozzle gaps.Type: ApplicationFiled: August 11, 2016Publication date: November 22, 2018Applicant: FONG'S EUROPE GMBHInventor: Johannes SCHMITZ
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Patent number: 10000873Abstract: An apparatus for treatment of a strand-like textile material in the form of a continuous material rope, which is circulated during at least part of the treatment, includes: an elongated, essentially tubular treatment container; a transport nozzle array to which a transport medium flow can be applied; and a transport section adjoining the transport nozzle array. The transport section terminates on a material rope inlet side in a storage section of the treatment container. The storage section accommodates a folded material rope pile and includes: a gliding bottom extending at a distance above a container wall below, the gliding bottom extending from the material rope inlet side of the storage section to a material rope outlet side in vicinity of the transport nozzle array; and at least one unit provided for changing an inclination of the gliding bottom from the material rope inlet side toward the material rope outlet side.Type: GrantFiled: September 20, 2014Date of Patent: June 19, 2018Assignee: FONG'S EUROPE GMBHInventor: Johannes Schmitz
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Patent number: 9982378Abstract: A device for treatment of a strand-like textile fabric in the form of an endless fabric strand, includes: a lockable treatment container; a transport nozzle arrangement which can be subjected to a first transport medium flow; and a transport section adjoining the transport nozzle arrangement. The transport section terminates on a fabric strand inlet side in a storage section of the lockable treatment container, and the storage section accommodates a folded fabric strand pile. The transport nozzle arrangement includes a transport nozzle with a polygonal nozzle inlet opening and an outlet part having a polygonal cross-section, for the fabric strand. The outlet part is appropriately adapted in view of its dimensions. The nozzle gap is adjustable and is delimited all the way around on at least one side by a plurality of straight nozzle elements that each have a cross-sectional shape that is essentially part-cylindrical.Type: GrantFiled: September 20, 2014Date of Patent: May 29, 2018Assignee: FONG'S EUROPE GMBHInventor: Johannes Schmitz