Patents by Inventor Johannes Stadlmann

Johannes Stadlmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Superior Neutralization of SARS-CoV-2 by Deglycosylated Human Angiotensin Converting Enzyme 2 (ACE2)
    Publication number: 20240043821
    Abstract: The present invention relates to an ACE2 polypeptide lacking an N-linked glycosylation or comprising a truncated N-linked glyco-sylation, e.g., at an amino acid corresponding to Asn90 and/or Asn322 of SEQ ID NO: 1; its use in a treatment of a coronavirus infection and methods of manufacturing the ACE2 polypeptide.
    Type: Application
    Filed: December 10, 2021
    Publication date: February 8, 2024
    Inventors: Josef PENNINGER, Johannes STADLMANN
  • Modified expression of prolyl-4-hydroxylase in physcomitrella patens
    Patent number: 10174334
    Abstract: The field of the invention relates to a method for the production of a recombinant protein in a plant-based system comprising the steps of providing a plant-based system comprising a modulation for a plant endogenous prolyl-4-hydroxylase gene, delivering a gene encoding the recombinant protein into the plant-based system, and cultivating the plant-based system for the expression of the gene encoding the recombinant protein. The field of the invention further relates to a recombinant protein, which has been produced in a plant-based system. A plant-based system and use of the recombinant protein are also provided.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: January 8, 2019
    Assignees: ALBERT-LUDWIGS-UNIVERSITAET FREIBURG, UNIVERSITAET FUER BODENKULTUR WIEN
    Inventors: Ralf Reski, Juliana Parsons, Friedrich Altmann, Manuela Graf, Eva Decker, Johannes Stadlmann
  • MODIFIED EXPRESSION OF PROLYL-4-HYDROXYLASE IN PHYSCOITRELLA PATENS
    Publication number: 20160208275
    Abstract: The field of the invention relates to a method for the production of a recombinant protein in a plant-based system comprising the steps of providing a plant-based system comprising a modulation for a plant endogenous prolyl-4-hydroxylase gene, delivering a gene encoding the recombinant protein into the plant-based system, and cultivating the plant-based system for the expression of the gene encoding the recombinant protein. The field of the invention further relates to a recombinant protein, which has been produced in a plant-based system. A plant-based system and use of the recombinant protein are also provided.
    Type: Application
    Filed: May 5, 2014
    Publication date: July 21, 2016
    Inventors: Ralf Reski, Juliana Parsons, Friedrich Altmann, Manuela Graf, Eva Decker, Johannes Stadlmann