Abstract: The present technology relates to a method and instrument for classifying a sample. The method collects raw data from an analytical instrument (e.g., LC-MS), quantifies consistency parameters from the raw chromatographic data (e.g., peak detection) by assigning criteria and determining probability ratios, and constructs a learning model quantitation step by weighing the presence, absence, or modulation of one or more factors of the one or more samples against a decision criterion for positivity. The method can then apply the learning model to an unknown sample to detect the presence, absence, or modulation of one or more factors in the unknown sample such as the presence, absence, or modulation of a disease state or multiple disease states.

Abstract: Exemplary embodiments pertain to methods, mediums, and systems for using molecular properties of chemical compounds to quantify error or variation in collision cross-section predictions. For example, the CCS prediction may determine a location of charge on the compound, and the molecular properties (such as the length normalized residue value or Van der Waals volume of the compound) may be used to assign an error value to the prediction. These error values may be used to build a model of the chemical compound using the error or variance, where the compound is capable of exhibiting more than one value for the CCS value.

Abstract: A system including a photovoltaic panel having a first heat exchanger for absorbing heat from the panel and/or from the environment by a heat exchanging fluid, connected to a heat pump. A second heat exchanger is provided for absorbing heat by the heat exchanging fluid and a control means for controlling a flow of the heat exchanging fluid through the first heat exchanger and/or the second heat exchanger. The heat pump is arranged to cool the heat exchanging fluid. The system has the following operating modes: a first mode in which cooled heat exchanging fluid is fed to the first heat exchanger; and a second mode in which cooled heat exchanging fluid is fed to the second heat exchanger and then fed to the first heat exchanger.

Abstract: A frame for a liquid-throughflowable 3D fabric includes two first frame parts lying opposite each other, where each first frame part is configured to lie against at least a first part of a peripheral edge of the 3D fabric and to close the fabric at least substantially liquid-tightly along the first part of the peripheral edge. An assembly with such a frame and liquid-throughflowable 3D fabric, where the first parts of the peripheral edge of the 3D fabric are closed at least substantially liquid-tightly by the frame. A 3D fabric includes two main surfaces which are connected to each other along at least a part of the peripheral edge of the 3D fabric.

Abstract: Provided herein are methods, techniques and processes for selecting one or more peptides for virus detection (e.g., influenza, SARS-CoV-2) in clinical samples using mass spectrometry. Methods for selecting a combination of peptides to identify one or more disease states in a patient can include: (i) selecting the one or more disease states; (ii) collecting information on proteins associated with the one or more disease states being present within the subject; (ii) in silico digesting individual proteins associated with the one or more disease state to obtain possible workflow peptides; (iv) collecting filtering data associated with the possible workflow peptides; (iv) analyzing the possible workflow peptides for coverage of the one or more disease states and for mass spectrometry detection and resolution; and (iv) selecting the combination of peptides from the possible workflow peptides based on the analyzing step.

Abstract: A new and distinct cultivar of Apple tree named ‘GALA MGCP’, characterized by its upright to outwardly spreading plant habit; moderately vigorous growth habit; after flower senescence, receptacles are reddish pink in color; relatively early fruit-coloring; numerous fruit produced per plant; and high quality fruits that are yellow in color heavily blushed with red.

Abstract: A system and method are disclosed in the field of preparing a catheter for use in a patient, in particular a catheter of an intravascular blood pump, more specifically for properly purging and de-airing the catheter. The catheter comprises an elongate tubular portion and a connected device. The elongate tubular portion is configured to be inserted into a patient's blood vessel and defines a lumen. The connected device is connected to the elongate tubular portion and has a cavity, which may accommodate a drive unit of the blood pump, and which is in fluid communication with the lumen of the elongate tubular portion. In order to securely de-air the system, a sensor, such as an accelerometer, for detecting an orientation of the connected device is provided, and a user may be guided to correct the orientation of the connected device for proper purging.

Abstract: The present disclosure relates to methods and workflows for processing and analyzing clinical samples (e.g., nasal swabs, throat swabs, plasma samples, urine, etc.) In general, the methods and workflows involve the detection of an infectious state and are improved over contemporary methods due to increased throughput with improved resolution of positive results.

Abstract: A method for monitoring the load which is exerted on a roof includes the following steps: providing a roof with an external surface on which a load can be exerted by, for example, a layer of water or snow, providing a sensor for detecting a phenomenon related to the load which is exerted on the roof, monitoring the phenomenon with the sensor, storing at least one predetermined value for the phenomenon, emitting a signal when the value for the phenomenon detected by the sensor exceeds a predetermined value.

Abstract: The invention provides a plastics composition including polyethylene terephtalate (PET), chain extending agent, compatibilising agent, and one or more of polyolefin (PO), polyamide (PA), and vinyl thermoplastics. The plastics composition may include one or more of an impact modifier, an extrusion aid, lubricant, a reinforcing filler, flame retardant, organic filler, foaming agent or other modifying additive. The plastics composition may be a thermoplastics composition. The PET may include post consumer PET. At least 30% by mass of the PET may be post consumer PET, typically at least 50% by mass, and even in excess of 90% by mass. It may also be 100% virgin—of all the different grades commercially available—inclusive of PET G co-polymer. The invention extends to a process and to items made of the composition.

Abstract: The invention provides a vector which is capable of the expression of a vascular endothelial growth factor wherein the vector comprises a modified PCMV promoter. The invention further provides use of a vector which is capable of and expressing a vascular endothelial growth factor (VEGF) for the regulation of endothelial function, angiogenesis and arteriogenesis. The invention further comprises use of a vector which is capable of the expression of a vascular endothelial growth factor (VEGF) for the prophylactic treatment of arterial diseases and/or bone marrow diseases and/or neural diseases.

Abstract: A magnetoinductive flowmeter for measuring the flow rate of a moving medium includes a measuring tube conducting the medium, and an insert provided in the measuring tube. The insert consists of at least one first part and one second part which first part is introduced into the measuring tube from one end of the measuring tube while the second part, introduced into the measuring tube from the other end of the measuring tube, is joined with the first part in leak-proof fashion. The result is an easy-to-install insert that ensures secure and maintainable retention.

Abstract: The use of complex coacervates of two or more biopolymer materials, preferably at least one of these being gelatin, as a fat-replacing ingredient. The complex coacervates may be used in foods and cosmetics and preferably are of substantially spherical or elliptical shape and have an average D.sub.3,2 particle size, of from 0.2 to 100 microns.

Abstract: The invention concerns casein-containing dispersions, mixed with denatured protein containing compounds. The pH of the mixture is 4.8-5.2, which pH is regulated by stopping of the milk fermentation by heating. The dispersions can be used as a fat replacer in food products such as dressings, toppings, mayonnaises, frozen deserts, cheese products, and spreads.

Abstract: An edible plastic composition contains at least 5 wt. % of heat-denatured protein, the heat-denatured protein mainly being a dispersion in the form of non-aggregated protein-based macrocolloidal particles having a size in the range of from 0.1 to 10 microns. It is suitable as a low calorie fat replacer in food products and for topical applications and is prepared by successive heating and concentrating steps in which an aqueous composition comprising less than 15% by weight of the water, of heat-denaturable protein is at least partly denatured and the protein concentration of the aqueous composition is at least doubled and at least part of any soluble protein is removed.The present process for instance offers the advantage of not requiring complicated apparatus, and moreover is easy to control.

Abstract: Fibers containing casein and at least one heat-settable protein are prepared by dry-spinning an aqueous protein mixture containing calcium- and phosphate ions at a temperature below the gelling point of the protein mixture and drying the fibers obtained. The fibers are hydrated, and incorporated into a meat analogue mixture as texture-imparting materials.

Abstract: A process for producing edible protein fibres by dry-spinning an aqueous mixture based on milk solids in which the ratio of calcium ions to the casein present is reduced to a value below 0.85 mM Ca.sup.2+ /g. casein.The fibres obtained according to this process can be used as a fibrous component in reformed meat formulations or as an ingredient for protein-enriched snacks.

Abstract: Fibres containing casein and at least one heat-settable protein are prepared by dry-spinning an aqueous protein mixture containing calcium- and phosphate ions at a temperature below the gelling point of the protein mixture and drying the fibres obtained.

Abstract: A new and distinct cultivar of Apple tree named ‘GALA MGCP’, characterized by its upright to outwardly spreading plant habit; moderately vigorous growth habit; after flower senescence, receptacles are reddish pink in color; relatively early fruit-coloring; numerous fruit produced per plant; and high quality fruits that are yellow in color heavily blushed with red.