Patents by Inventor Johannes Wilhelmus Leonardus Boumans

Johannes Wilhelmus Leonardus Boumans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8835143
    Abstract: The invention relates to a method for the preparation of hybrid cross-linked enzyme-silica aggregates including the steps of taking up enzyme molecules in a solvent, precipitating the enzyme molecules using a precipitation agent, and adding an alkoxysilane and crosslinking the mixture of alkoxysilane and precipitated enzyme aggregates, using a crosslinking agent comprising an aldehyde, to obtain hybrid crosslinked enzyme-silica aggregates.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: September 16, 2014
    Assignee: Clea Technologies BV
    Inventors: Willem Robert Klaas Schoevaart, Lukas Michael Van Langen, Ronald Tako Marinus van Den Dool, Johannes Wilhelmus Leonardus Boumans
  • Patent number: 8771649
    Abstract: This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing antdaries or flavoring compounds and for pharmaceutical and/or nutraceutical applications.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: July 8, 2014
    Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNO
    Inventors: Henricus Matheus Wilhelmus Maria Thijssen, Roy Christiaan Montijn, Johannes Wilhelmus Timmermans, Theodoor Maximiliaan Slaghek, Jacobus Johannes Frederick van Veen, Johannes Wilhelmus Leonardus Boumans
  • Patent number: 8771650
    Abstract: This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing anti-caries or flavoring compounds and for pharmaceutical and/or nutraceutical applications.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: July 8, 2014
    Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNO
    Inventors: Henricus Matheus Wilhelmus Maria Thijssen, Roy Christiaan Montijn, Johannes Wilhelmus Timmermans, Theodoor Maximiliaan Slaghek, Jacobus Johannes Frederik van Veen, Johannes Wilhelmus Leonardus Boumans
  • Patent number: 8431375
    Abstract: The invention relates to a marking system for marking objects wherein said system comprises a microparticle comprising a cross-linked polymer and a marker component wherein the release of said marker component is triggered by contact of the microparticle with an external stimulus and wherein said polymer is a carbohydrate or a protein.
    Type: Grant
    Filed: July 4, 2008
    Date of Patent: April 30, 2013
    Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNO
    Inventors: Randolph Peter Happe, Ronald Tako Marinus Van Den Dool, Johannes Wilhelmus Timmermans, Johannes Wilhelmus Leonardus Boumans
  • Publication number: 20120027694
    Abstract: This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing anti-caries or flavoring compounds and for pharmaceutical and/or nutraceutical applications.
    Type: Application
    Filed: October 7, 2011
    Publication date: February 2, 2012
    Inventors: Henricus Matheus Wilhelmus Maria Thijssen, Roy Christiaan Montijn, Johannes Wilhelmus Timmermans, Theodoor Maximiliaan Slaghek, Jacobus Johannes Frederik van Veen, Johannes Wilhelmus Leonardus Boumans
  • Patent number: 7977066
    Abstract: Described is a method for selectively isolating tryptophan containing peptides from an aqueous peptide mixture, including the steps of controlling the pH of the aqueous peptide mixture to 4.0-6.0, forming a precipitate of tryptophan containing peptides, and isolating the precipitated peptides. The aqueous peptide mixture is preferably obtained by enzymatic cleavage at acidic pH of a protein source. Further, peptides having a Trp content of 8-15 w/w % and the use thereof as a food additive and as an active ingredient in a medicament are described.
    Type: Grant
    Filed: October 23, 2008
    Date of Patent: July 12, 2011
    Assignee: Campina Melkunie B.V.
    Inventors: Leon Franciscus Mallee, Petronella Wilhelmina Josephina Rosa Caessens, Johannes Wilhelmus Leonardus Boumans
  • Publication number: 20110129865
    Abstract: The invention relates to a marking system for marking objects wherein said system comprises a microparticle comprising a cross-linked polymer and a marker component wherein the release of said marker component is triggered by contact of the microparticle with an external stimulus and wherein said polymer is a carbohydrate or a protein.
    Type: Application
    Filed: July 4, 2008
    Publication date: June 2, 2011
    Applicant: Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO
    Inventors: Randolph Peter Happe, Ronald Tako Marinus Van Den Dool, Johannes Wilhelmus Timmermans, Johannes Wilhelmus Leonardus Boumans
  • Publication number: 20110059206
    Abstract: The invention pertains to the use of an ?-1,3/?-1,6-glucan having a molecular weight of at least 10 kDa as a low-viscosity dietary fibre, and to liquid food compositions containing at least one of carbohydrates, fats and proteins and further containing such a glucan at a level of at least 1 wt. %.
    Type: Application
    Filed: March 3, 2009
    Publication date: March 10, 2011
    Inventors: Johannes Wilhelmus Leonardus Boumans, Albert Jan Jacob Woortman
  • Patent number: 7491410
    Abstract: Transglutaminase inhibitor containing composition obtainable from milk, in particular from a whey fraction obtainable from skimmed milk by forming a curd from the milk, separating the curd from the whey in a centrifugation step followed by subjecting the whey to an ultrafiltration step or, alternatively, by subjecting the skimmed milk to a diafiltration step, a method for the production of a transglutaminase inhibitor and the use of the transglutaminase inhibitor in the production of food or pharmaceutical compositions and to the use in the preparation of a medicament for the treatment of pathologies.
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: February 17, 2009
    Assignee: Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek TNO
    Inventors: Govardus Adrianus Hubertus de Jong, Johannes Wilhelmus Leonardus Boumans, Gerrit Wijngaards
  • Publication number: 20080296231
    Abstract: The invention relates to a method for the preparation of cross-linked enzyme aggregates, which method is characterised by the following steps: i. generating aldehyde groups on enzyme molecules that may or may not be dissolved in a suitable solvent; ii. precipitating the enzyme molecules using a suitable precipitation agent; iii. cross-linking the precipitated enzyme molecules provided with aldehyde groups, using an amine composition, yielding cross-linked enzyme aggregates with improved properties.
    Type: Application
    Filed: October 27, 2005
    Publication date: December 4, 2008
    Applicant: CLEA TECHNOLOGIES BV
    Inventors: Willem Robert Klaas Schoevaart, Lukas Michael Van Langen, Ronald Tako Marinus Van Den Dool, Johannes Wilhelmus Leonardus Boumans
  • Publication number: 20080241878
    Abstract: The present invention provides methods for enzymatic cross-linking of a protein comprising performing a reaction for enzymatic cross-linking of said protein in the presence of a phenolic saccharide, wherein said reaction comprises the step of forming protein-protein cross-links. The present invention further provides a cross-linked protein obtainable by a method according to the invention as well as a protein that is cross-linked by a phenolic saccharide and the use of such proteins in a foodstuff. The invention also provides a foodstuff comprising a cross-linked protein of the invention as well as the use of a phenolic saccharide as a cross-linking agent for proteins.
    Type: Application
    Filed: August 10, 2005
    Publication date: October 2, 2008
    Inventors: Johannes Wilhelmus Leonardus Boumans, Ricardo Marinus Albertus Nagtegaal, Albertus Dunnewind, Randolph Peter Happe, Martin Anton Bos, Merete Faergemand, Peter Degn
  • Publication number: 20040058866
    Abstract: Described is a method for selectively isolating tryptophan containing peptides from an aqueous peptide mixture, including the steps of controlling the pH of the aqueous peptide mixture to 4.0-6.0, forming a precipitate of tryptophan containing peptides, and isolating the precipitated peptides.
    Type: Application
    Filed: October 20, 2003
    Publication date: March 25, 2004
    Inventors: L.eon Franciscus Mallee, Petronella Wilhelmina Josephina Rosa Caessens, Johannes Wilhelmus Leonardus Boumans