Patents by Inventor Johannes Wilhelmus Leonardus Boumans
Johannes Wilhelmus Leonardus Boumans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8835143Abstract: The invention relates to a method for the preparation of hybrid cross-linked enzyme-silica aggregates including the steps of taking up enzyme molecules in a solvent, precipitating the enzyme molecules using a precipitation agent, and adding an alkoxysilane and crosslinking the mixture of alkoxysilane and precipitated enzyme aggregates, using a crosslinking agent comprising an aldehyde, to obtain hybrid crosslinked enzyme-silica aggregates.Type: GrantFiled: June 16, 2011Date of Patent: September 16, 2014Assignee: Clea Technologies BVInventors: Willem Robert Klaas Schoevaart, Lukas Michael Van Langen, Ronald Tako Marinus van Den Dool, Johannes Wilhelmus Leonardus Boumans
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Patent number: 8771649Abstract: This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing antdaries or flavoring compounds and for pharmaceutical and/or nutraceutical applications.Type: GrantFiled: May 28, 2004Date of Patent: July 8, 2014Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNOInventors: Henricus Matheus Wilhelmus Maria Thijssen, Roy Christiaan Montijn, Johannes Wilhelmus Timmermans, Theodoor Maximiliaan Slaghek, Jacobus Johannes Frederick van Veen, Johannes Wilhelmus Leonardus Boumans
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Patent number: 8771650Abstract: This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing anti-caries or flavoring compounds and for pharmaceutical and/or nutraceutical applications.Type: GrantFiled: October 7, 2011Date of Patent: July 8, 2014Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNOInventors: Henricus Matheus Wilhelmus Maria Thijssen, Roy Christiaan Montijn, Johannes Wilhelmus Timmermans, Theodoor Maximiliaan Slaghek, Jacobus Johannes Frederik van Veen, Johannes Wilhelmus Leonardus Boumans
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Patent number: 8431375Abstract: The invention relates to a marking system for marking objects wherein said system comprises a microparticle comprising a cross-linked polymer and a marker component wherein the release of said marker component is triggered by contact of the microparticle with an external stimulus and wherein said polymer is a carbohydrate or a protein.Type: GrantFiled: July 4, 2008Date of Patent: April 30, 2013Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNOInventors: Randolph Peter Happe, Ronald Tako Marinus Van Den Dool, Johannes Wilhelmus Timmermans, Johannes Wilhelmus Leonardus Boumans
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Publication number: 20120027694Abstract: This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing anti-caries or flavoring compounds and for pharmaceutical and/or nutraceutical applications.Type: ApplicationFiled: October 7, 2011Publication date: February 2, 2012Inventors: Henricus Matheus Wilhelmus Maria Thijssen, Roy Christiaan Montijn, Johannes Wilhelmus Timmermans, Theodoor Maximiliaan Slaghek, Jacobus Johannes Frederik van Veen, Johannes Wilhelmus Leonardus Boumans
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Patent number: 7977066Abstract: Described is a method for selectively isolating tryptophan containing peptides from an aqueous peptide mixture, including the steps of controlling the pH of the aqueous peptide mixture to 4.0-6.0, forming a precipitate of tryptophan containing peptides, and isolating the precipitated peptides. The aqueous peptide mixture is preferably obtained by enzymatic cleavage at acidic pH of a protein source. Further, peptides having a Trp content of 8-15 w/w % and the use thereof as a food additive and as an active ingredient in a medicament are described.Type: GrantFiled: October 23, 2008Date of Patent: July 12, 2011Assignee: Campina Melkunie B.V.Inventors: Leon Franciscus Mallee, Petronella Wilhelmina Josephina Rosa Caessens, Johannes Wilhelmus Leonardus Boumans
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Publication number: 20110129865Abstract: The invention relates to a marking system for marking objects wherein said system comprises a microparticle comprising a cross-linked polymer and a marker component wherein the release of said marker component is triggered by contact of the microparticle with an external stimulus and wherein said polymer is a carbohydrate or a protein.Type: ApplicationFiled: July 4, 2008Publication date: June 2, 2011Applicant: Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNOInventors: Randolph Peter Happe, Ronald Tako Marinus Van Den Dool, Johannes Wilhelmus Timmermans, Johannes Wilhelmus Leonardus Boumans
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Publication number: 20110059206Abstract: The invention pertains to the use of an ?-1,3/?-1,6-glucan having a molecular weight of at least 10 kDa as a low-viscosity dietary fibre, and to liquid food compositions containing at least one of carbohydrates, fats and proteins and further containing such a glucan at a level of at least 1 wt. %.Type: ApplicationFiled: March 3, 2009Publication date: March 10, 2011Inventors: Johannes Wilhelmus Leonardus Boumans, Albert Jan Jacob Woortman
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Patent number: 7491410Abstract: Transglutaminase inhibitor containing composition obtainable from milk, in particular from a whey fraction obtainable from skimmed milk by forming a curd from the milk, separating the curd from the whey in a centrifugation step followed by subjecting the whey to an ultrafiltration step or, alternatively, by subjecting the skimmed milk to a diafiltration step, a method for the production of a transglutaminase inhibitor and the use of the transglutaminase inhibitor in the production of food or pharmaceutical compositions and to the use in the preparation of a medicament for the treatment of pathologies.Type: GrantFiled: October 30, 2001Date of Patent: February 17, 2009Assignee: Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek TNOInventors: Govardus Adrianus Hubertus de Jong, Johannes Wilhelmus Leonardus Boumans, Gerrit Wijngaards
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Publication number: 20080296231Abstract: The invention relates to a method for the preparation of cross-linked enzyme aggregates, which method is characterised by the following steps: i. generating aldehyde groups on enzyme molecules that may or may not be dissolved in a suitable solvent; ii. precipitating the enzyme molecules using a suitable precipitation agent; iii. cross-linking the precipitated enzyme molecules provided with aldehyde groups, using an amine composition, yielding cross-linked enzyme aggregates with improved properties.Type: ApplicationFiled: October 27, 2005Publication date: December 4, 2008Applicant: CLEA TECHNOLOGIES BVInventors: Willem Robert Klaas Schoevaart, Lukas Michael Van Langen, Ronald Tako Marinus Van Den Dool, Johannes Wilhelmus Leonardus Boumans
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Publication number: 20080241878Abstract: The present invention provides methods for enzymatic cross-linking of a protein comprising performing a reaction for enzymatic cross-linking of said protein in the presence of a phenolic saccharide, wherein said reaction comprises the step of forming protein-protein cross-links. The present invention further provides a cross-linked protein obtainable by a method according to the invention as well as a protein that is cross-linked by a phenolic saccharide and the use of such proteins in a foodstuff. The invention also provides a foodstuff comprising a cross-linked protein of the invention as well as the use of a phenolic saccharide as a cross-linking agent for proteins.Type: ApplicationFiled: August 10, 2005Publication date: October 2, 2008Inventors: Johannes Wilhelmus Leonardus Boumans, Ricardo Marinus Albertus Nagtegaal, Albertus Dunnewind, Randolph Peter Happe, Martin Anton Bos, Merete Faergemand, Peter Degn
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Publication number: 20040058866Abstract: Described is a method for selectively isolating tryptophan containing peptides from an aqueous peptide mixture, including the steps of controlling the pH of the aqueous peptide mixture to 4.0-6.0, forming a precipitate of tryptophan containing peptides, and isolating the precipitated peptides.Type: ApplicationFiled: October 20, 2003Publication date: March 25, 2004Inventors: L.eon Franciscus Mallee, Petronella Wilhelmina Josephina Rosa Caessens, Johannes Wilhelmus Leonardus Boumans