Abstract: The present invention features methods of treating lung cancer (e.g., NSCLC) with an anti-PD-L1 antibody and tremelimumab in a subject identified as having a PD-L1 negative tumor.

Abstract: A plastic container for a particulate product has a footprint and includes a base and at least two and preferably four sides upstanding therefrom which generally define a container main interior volume. A top connects to the sides and includes a large opening which is closed by a lid. One side includes a pass-through handle located therein having a generally vertical segment which may define a hollow cavity in communication with the main interior volume. The opening of the top is sufficiently large to extend over a portion of the hollow cavity; or is sufficiently wide to receive about a 5? diameter cylinder therethrough, and has a ratio of a minimum span to a bottom diagonal of at least about 2:3. A shoulder between the top and sides has an angle of less than about 40°. The handle is configured and sized for easy grasping and holding.

Abstract: A plastic container for a particulate product has a footprint and includes a base and at least two and preferably four sides upstanding therefrom which generally define a container main interior volume. A top connects to the sides and includes a large opening which is closed by a lid. One corner includes a pass-through handle located therein having a generally vertical segment which may define a hollow cavity in communication with the main interior volume. The opening of the top is sufficiently large to extend over a portion of the hollow cavity; or is sufficiently wide to receive about a 5? diameter cylinder therethrough, and has a ratio of a minimum span to a bottom diagonal of at least about ?. A shoulder between the top and sides has an angle of less than about 40°. The handle is configured and sized for easy grasping and holding.

Abstract: A carton having a door and a method of making a carton having a door, the carton being adapted for automated assembly and/or loading by reducing or eliminating interference between side panels of a door and product during loading and use of the door. In an aspect of the invention, the door side panels are slidable within a protected region formed between adjacent panels of the carton.

Abstract: A carton having a door and a method of making a carton having a door, the carton being adapted for automated assembly and/or loading by reducing or eliminating interference between side panels of a door and product during loading and use of the door. In an aspect of the invention, the door side panels are slidable within a protected region formed between adjacent panels of the carton.

Abstract: A convertible carrying bag/envelope suitable for carrying and shipping printed materials and other items. The bag/envelope provides a handle that may be used to carry the bag/envelope while allowing items to be placed into or removed from the interior of the bag. The bag/envelope provides an exterior flap that is operative for sealing the bag, on which delivery indicia is printed, so that it may be shipped via a small package delivery service. To prepare the bag for shipping, the handle is folded into the interior of the bag. The flap is then extended across the opening and affixed to the opposite panel using the pressure-sensitive adhesive provided on the flap.