Patents by Inventor John A. Bogdan, Jr.

John A. Bogdan, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the production of bacterial toxins
    Patent number: 7829321
    Abstract: Methods and compositions are provided for the enhanced production of bacterial toxins in large-scale cultures. Specifically, methods and compositions for reducing bacterial toxin expression inhibitors are providing including, but not limited to, addition of toxin expression inhibitor binding compounds, culture media having reduced concentrations of toxin inhibitor metabolic precursors and genetically modified toxogenic bacteria lacking enzymes required to metabolize the toxin inhibitor metabolic precursors.
    Type: Grant
    Filed: November 29, 2005
    Date of Patent: November 9, 2010
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Milan S. Blake, John A. Bogdan, Jr., Javier Nazario-Larrieu
  • Method for the production of bacterial toxins
    Patent number: 7790185
    Abstract: Methods and compositions are provided for the enhanced production of bacterial toxins in large-scale cultures. Specifically, methods and compositions for reducing bacterial toxin expression inhibitors are providing including, but not limited to, addition of toxin expression inhibitor binding compounds, culture media having reduced concentrations of toxin inhibitor metabolic precursors and genetically modified toxogenic bacteria lacking enzymes required to metabolize the toxin inhibitor metabolic precursors.
    Type: Grant
    Filed: November 1, 2005
    Date of Patent: September 7, 2010
    Assignees: Baxter International Inc., Bacter Healthcare S.A.
    Inventors: Milan S. Blake, John A. Bogdan, Jr., Javier Nazario-Larrieu
  • Method for the production of bacterial toxins
    Patent number: 7045314
    Abstract: Methods and compositions are provided for the enhanced production of bacterial toxins in large-scale cultures. Specifically, methods and compositions for reducing bacterial toxin expression inhibitors are providing including, but not limited to, addition of toxin expression inhibitor binding compounds, culture media having reduced concentrations of toxin inhibitor metabolic precursors and genetically modified toxogenic bacteria lacking enzymes required to metabolize the toxin inhibitor metabolic precursors.
    Type: Grant
    Filed: April 4, 2001
    Date of Patent: May 16, 2006
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Milan S. Blake, John A. Bogdan, Jr., Javier Nazario-Larrieu
  • Method for the production of bacterial toxins
    Patent number: 7018813
    Abstract: Methods and compositions are provided for the enhanced production of bacterial toxins in large-scale cultures. Specifically, methods and compositions for reducing bacterial toxin expression inhibitors are providing including, but not limited to, addition of toxin expression inhibitor binding compounds, culture media having reduced concentrations of toxin inhibitor metabolic precursors and genetically modified toxogenic bacteria lacking enzymes required to metabolize the toxin inhibitor metabolic precursors.
    Type: Grant
    Filed: October 3, 2003
    Date of Patent: March 28, 2006
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Milan S. Blake, John A. Bogdan, Jr., Javier Nazario-Larrieu
  • Method for the production of bacterial toxins
    Patent number: 6686180
    Abstract: Methods and compositions are provided for the enhanced production of bacterial toxins in large-scale cultures. Specifically, methods and compositions for reducing bacterial toxin expression inhibitors are providing including, but not limited to, addition of toxin expression inhibitor binding compounds, culture media having reduced concentrations of toxin inhibitor metabolic precursors and genetically modified toxogenic bacteria lacking enzymes required to metabolize the toxin inhibitor metabolic precursors.
    Type: Grant
    Filed: April 4, 2001
    Date of Patent: February 3, 2004
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Milan S. Blake, John A. Bogdan, Jr., Javier Nazario-Larrieu