Patents by Inventor John A. Broadhurst

John A. Broadhurst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11989816
    Abstract: A method of managing resources in a graphics processing pipeline includes, in response to selecting a task for execution within a texture/shading unit, allocating to the task both a static allocation of temporary registers for the entire task and a dynamic allocation of temporary registers. The dynamic allocation comprises temporary registers used by a first phase of the task only and the static allocation of temporary registers comprises any temporary registers that are used by the program and are live at a boundary between two phases. When the task subsequently reaches a boundary between two phases, the dynamic allocation of temporary registers are freed and a new dynamic allocation of temporary registers for a next phase of the task is allocated to the task.
    Type: Grant
    Filed: February 25, 2022
    Date of Patent: May 21, 2024
    Assignee: Imagination Technologies Limited
    Inventors: Panagiotis Velentzas, John W. Howson, Richard Broadhurst
  • Publication number: 20240119662
    Abstract: Methods and graphics processing units for processing a plurality of fragments in a graphics processing system. A received first fragment is processed by performing an early depth test with hidden surface removal logic using a depth buffer; in response to the first fragment passing the early depth test, executing one or more instructions of a shader program for the first fragment on the processing logic to determine the property of the first fragment; and after the determination of the property of the first fragment, performing a late depth test on the first fragment with the hidden surface removal logic using the depth buffer. After said receiving a first fragment, a second fragment to be processed is received, wherein the second fragment does not have a shader-dependent property. The second fragment is processed by, before said late depth test is performed on the first fragment, performing an early depth test on the second fragment with the hidden surface removal logic.
    Type: Application
    Filed: June 22, 2023
    Publication date: April 11, 2024
    Inventors: Panagiotis Velentzas, John W. Howson, Richard Broadhurst
  • Publication number: 20120319852
    Abstract: A device that attaches to a bag provides an indication when the volume of matter in the bag reaches a predetermined value. The device includes a detachment detector that provides a detachment signal when the device detaches from the bag. First and second arms may be pivotally connected to each other and biased in a direction towards each other adjacent first ends of the arms. The first and second arms in use engage opposing sides of the bag. At least one bag level indicator provides a bag level signal when the volume of matter in the bag reaches the predetermined value.
    Type: Application
    Filed: November 19, 2010
    Publication date: December 20, 2012
    Applicant: The New Castle Upon Tyne Hospitals NHS Foundation Trust
    Inventors: Charlotte Ruth Platten, Robert Tapper, Michael John Broadhurst
  • Publication number: 20070215185
    Abstract: Cleaning apparatus, particularly suitable for cleaning the wheels of golf trolleys (20) comprises a support surface (3) along which the trolley is rolled from an entry end (27) to an exit end (28) and manifolds (16), (17) which spray water downwardly and outwardly towards the respective wheels. The rolling surface and inner surface of which each wheel is cleaned directly by the water jets whilst the outer surface of each wheel is cleaned by water bouncing from side walls (6), (7) of the auxiliary cleaning apparatus (30) may be provided for cleaning golf clubs.
    Type: Application
    Filed: March 18, 2005
    Publication date: September 20, 2007
    Inventor: John Broadhurst
  • Patent number: 6867299
    Abstract: Disclosed are compounds of the general formula which are oxamide derivatives and inhibitors of the enzyme inosine monophosphate dehydrogenase (IMPDH).
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: March 15, 2005
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael John Broadhurst, Christopher Huw Hill, David Nigel Hurst, Philip Stephen Jones, Paul Brittain Kay, Ian Reginald Kilford, Robert Murray McKinnell
  • Patent number: 6281363
    Abstract: Hydrazine derivatives and their pharmaceutically acceptable salts useful for the treatment of inflammatory and autoimmune diseases, osteoarthritis, respiratory diseases, tumors, cachexia, cardiovascular disease, fever, hemorrhage, and sepsis.
    Type: Grant
    Filed: December 9, 1999
    Date of Patent: August 28, 2001
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael John Broadhurst, William Henry Johnson, Daryl Simon Walter
  • Patent number: 6265446
    Abstract: Hydrazine derivatives of the formula wherein R1 represents lower alkyl, lower alkenyl, lower cycloalkyl, lower cycloalkyl-lower alkyl, aryl or aryl-lower alkyl, R2 represents heterocyclyl or NR5R6, R3 represents hydrogen, lower alkyl, halo-lower alkyl, cyano-lower alkyl, hydroxy-lower alkyl, amino-lower alkyl, lower alkoxy-lower alkyl, lower alkoxycarbonyl-lower alkyl, lower cycloalkyl-lower alkyl, aryl-lower alkyl, heterocyclyl-lower alkyl, heterocyclylcarbonyl-lower alkyl, lower alkenyl, lower alkynyl, lower cycloalkyl, aryl, heteroaryl or aryl-lower alkyl, R4 represents lower alkyl, lower alkenyl, lower cycloalkyl, lower cycloalkyl-lower alkyl or a grouping of the formula -Z-aryl, -Z-heterocyclyl or —(CH2)n—, CH═CR7R8, R5 and R6 each independently represent hydrogen or lower alkyl, R7 and R8 each independently represent hydrogen or lower alkyl or R7 and R8 together represent lower alkylene in which one CH2 group is optionally replaced by a hetero atom, X and Z each repres
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: July 24, 2001
    Assignee: Hoffmann-La Roche Inc..
    Inventors: Michael John Broadhurst, William Henry Johnson, Daryl Simon Walter
  • Patent number: 6239151
    Abstract: The invention provides hydrazine derivatives of the formula wherein R1 is lower alkyl, lower alkenyl, lower cycloalkyl, lower cycloalkyl-lower alkyl, aryl or aryl-lower alkyl; R2 is an acyl group derived from an &agr;-, &bgr;-, &ggr;- or &dgr;-(amino, hydroxy or thiol)carboxylic acid in which the amino, hydroxy or thiol group is optionally lower alkylated or the amino group is optionally acylated, sulphonylated or amidated and in which any functional group present in a side-chain is optionally protected, or a group of the formula Het(CH2)mCO; R3 is hydrogen, lower alkyl, halo-lower alkyl, cyano-lower alkyl, amino-lower alkyl, hydroxy-lower alkyl, lower alkoxy-lower alkyl, lower alkoxycarbonyl-lower alkyl, lower cycloalkyl-lower alkyl, aryl-lower alkyl, heterocyclyl-lower alkyl, heterocyclylcarbonyl-lower alkyl, lower alkenyl, lower alkynyl, lower cycloalkyl, aryl-lower alkenyl, aryl or heterocyclyl; R4 is lower alkyl, lower alkenyl, lower cycloalkyl, lower cycloalkyl-lower alkyl or a groupin
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: May 29, 2001
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael John Broadhurst, William Henry Johnson, Daryl Simon Walter
  • Patent number: 6235787
    Abstract: Hydrazine derivatives of the formula wherein Y is CO or SO2; R1 is lower alkyl, lower alkenyl, lower cycloalkyl, lower cycloalkyl-lower alkyl, aryl or aryl-lower alkyl; R2 is lower alkyl, halo-lower alkyl, aryl-lower alkyl, aryl-lower alkenyl or aryl when Y is SO2 and is lower alkyl, halo-lower alkyl, lower alkoxy, lower alkoxycarbonyl, acyl, lower cycloalkyl, aryl, aryl-lower alkyl, aryl-lower alkoxy or NR5R6 when Y is CO; and R3 is hydrogen, lower alkyl optionally substituted by cyano, amino, hydroxy, lower alkoxy, lower alkoxycarbonyl, heterocyclyl or heterocyclylcarbonyl, lower alkenyl, lower alkynyl, lower cycloalkyl, lower cycloalkyl-lower alkyl, aryl-lower alkyl, aryl-lower alkenyl, aryl or heterocyclyl; or R2 and R3 together form the residue of a 5-, 6- or 7-membered cyclic amide, cyclic imide, cyclic sulphonamide or cyclic urethane group; R4 is lower alkyl, hydroxy-lower alkyl, lower alkenyl, lower cycloalkyl, lower cycloalkyl-lower alkyl or a group of the formula X-aryl, X-heteroar
    Type: Grant
    Filed: June 16, 1998
    Date of Patent: May 22, 2001
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael John Broadhurst, William Henry Johnson, Daryl Simon Walter
  • Patent number: 6066662
    Abstract: The invention provides hydroxylamine derivatives of formula (I) wherein A, R.sup.1, R.sup.2 and R.sup.3 have the significance given in the description, which are matrix metalloproteinase inhibitors and which also prevent TNF release. They are therefore useful for the control or prevention of degenerative joints diseases such as rheumatoid arthritis and osteoarthritis or for the treatment of invasive tumours, atherosclerosis or multiple sclerosis. They can be manufactured according to generally known methods.
    Type: Grant
    Filed: November 20, 1996
    Date of Patent: May 23, 2000
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael John Broadhurst, Paul Anthony Brown, William Henry Johnson
  • Patent number: 5731441
    Abstract: The invention provides hydroxamic acid derivatives of the general formula ##STR1## wherein R.sup.1 represents cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl; R.sup.2 represents a saturated 5- to 8-membered monocyclic or bridged N-heterocyclic ring, which N-heterocyclic ring is attached via the N atom and when it is monocyclic, optionally contains NR.sup.4, O, S, SO or SO.sub.2 as a ring member and/or is optionally substituted on one or more C atoms by hydroxy, lower alkyl, lower alkoxy, oxo, ketalized oxo, amino, mono(lower alkyl)amino, di(lower alkyl)amino,carboxy, lower alkoxycarbonyl, hydroxy-methyl, lower alkoxymethyl, carbamoyl, mono(lower alkyl)-carbamoyl, di(lower alkyl)carbamoyl or hydroxyimino; R.sup.3 represents a 5- or 6-membered N-heterocyclic ring which (a) is attached via the N atom, (b) optionally contains N, O and/or S, SO or SO.sub.
    Type: Grant
    Filed: October 29, 1996
    Date of Patent: March 24, 1998
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael John Broadhurst, Paul Anthony Brown, William Henry Johnson
  • Patent number: 5710167
    Abstract: The invention provides hydroxamic acid derivatives of the general formula ##STR1## wherein R.sup.1 represents cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl; R.sup.2 represents a saturated 5- to 8-membered monocyclic or bridged N-heterocyclic ring, which N-heterocyclic ring is attached via the N atom and when it is monocyclic, optionally contains NR.sup.4, O, S, SO or SO.sub.2 as a ring member and/or is optionally substituted on one or more C atoms by hydroxy, lower alkyl, lower alkoxy, oxo, ketalized oxo, amino, mono(lower alkyl)amino, di(lower alkyl)amino, carboxy, lower alkoxycarbonyl, hydroxy-methyl, lower alkoxymethyl, carbamoyl, mono(lower alkyl)-carbamoyl, di(lower alkyl)carbamoyl or hydroxy-imino; R.sup.3 represents a 5- or 6-membered N-heterocyclic ring which (a) is attached via the N atom, (b) optionally contains N, O and/or S, SO or SO.sub.
    Type: Grant
    Filed: October 29, 1996
    Date of Patent: January 20, 1998
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael John Broadhurst, Paul Anthony Brown, William Henry Johnson
  • Patent number: 5698690
    Abstract: The invention provides hydroxamic acid derivatives of the general formula ##STR1## wherein Bz represents benzyl; R.sup.1 represents cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl; R.sup.2 represents a saturated 5- to 8-membered monocyclic or bridged N-heterocyclic ring, which N-heterocyclic ring is attached via the N atom and when it is monocyclic, optionally contains NR.sup.4, O, S, SO or SO.sub.2 as a ring member and/or is optionally substituted on one or more C atoms by hydroxy, lower alkyl, lower alkoxy, oxo, ketalized oxo, amino, mono(lower alkyl)amino, di(lower alkyl)amino,carboxy, lower alkoxycarbonyl, hydroxy-methyl, lower alkoxymethyl, carbamoyl, mono(lower alkyl)-carbamoyl, di(lower alkyl)carbamoyl or hydroxy-imino; R.sup.3 represents a 5- or 6-membered N-heterocyclic ring which (a) is attached via the N atom, (b) optionally contains N, O and/or S, SO or SO.sub.
    Type: Grant
    Filed: October 29, 1996
    Date of Patent: December 16, 1997
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael John Broadhurst, Paul Anthony Brown, William Henry Johnson
  • Patent number: 5025641
    Abstract: An apparatus and method of making extremely pure high quality flake ice, said apparatus having a frame manufactured completely of a food grade polyethylene thermal plastic material with slidably mounted hydrostatic distributor, slidably mounted freezing plates and, ice slides which direct the ice into an ice conveyor means for removing the ice from within the frame work of the apparatus, the method includes running a freon gas/liquid mixture into the freezing plates, ice making water being introduced into the system flowing onto freezing plates, the ice shavings and meltings from manufacturing the ice are being combined with tap water and recirculated for use in making additional ice, the refrigerant is pumped into the plates through a compressor, boiled off inside the plates such that a combined liquid/vapor mixture falls from the plates through a section header, excess liquid is then dumped into an accumulated, the refrigerant vapor is drawn off the top of the accumulator and in turn is transported to the c
    Type: Grant
    Filed: February 24, 1989
    Date of Patent: June 25, 1991
    Inventor: John A. Broadhurst