Abstract: The present disclosure provides a cargo delivery fusion polypeptide comprising an endosomolytic polypeptide and a cell penetrating polypeptide; and compositions comprising the cargo delivery fusion polypeptide. The present disclosure also provides methods of delivering a cargo into a target eukaryotic cell, using a composition comprising an amphiphilic polypeptide.

Abstract: The present invention provides devices and methods that can prevent or ameliorate bronchoconstriction by stimulating neural activity, in contrast to those techniques based on denervation, ablation or blocking of neural activity. Methods and devices according to the invention may act responsively or on demand, can preserve neuronal structure and function and will be associated with minimal collateral side-effects. In particular, the invention provides devices and methods in which signals are delivered to the vagus nerve in order to stimulate neural activity in the vagal nerve.

Abstract: The present invention provides devices and methods that can prevent or ameliorate bronchoconstriction by stimulating neural activity, in contrast to those techniques based on denervation, ablation or blocking of neural activity. Methods and devices according to the invention may act responsively or on demand, can preserve neuronal structure and function and will be associated with minimal collateral side-effects. In particular, the invention provides devices and methods in which a signal is delivered to the vagus nerve, for example the cervical vagus nerve or the pulmonary branch of the vagus nerve, in order to stimulate neural activity in the vagal nerve.

Abstract: The present invention provides an implantable neuromodulation system for delivering an electrical signal to a nerve to stimulate, inhibit or block conduction of action potentials in the nerve. The system comprises a neural interface device comprising first and second electrodes; a signal generator and a first closed-loop controller configured to generate a control signal based a property of the signal based on a measured voltage across the first and second electrodes, and cause the signal generator to adjust the electrical signal to modify the property of the signal.

Abstract: A storage assembly includes top and bottom walls, a pair of end walls extending between the top and bottom walls and cooperating with the top and bottom walls to define an interior space, and at least one end surface configured to closely interfit with at least one end surface of an adjacent storage assembly that is substantially similar to the storage assembly at a predefined angular orientation such that a longitudinal axis of the storage assembly is angularly offset from a longitudinal axis of the adjacent storage assembly when the at least one end surface of the storage assembly is interfit with the at least one surface of the adjacent storage assembly The storage assembly may also include a pair of interior walls and a handle relief extending into the top wall and/or a frame assembly located between one of the end walls and one of the interior walls.

Abstract: An implantable neurostimulation system comprises at least one neural interface device for stimulating and/or inhibiting neural activity in a nerve such as the cervical vagus nerve. The device comprises first and second electrodes and at least one signal generator configured to generate first and second electrical signals that stimulate and/or inhibit neural activity in the nerve via the first and second electrodes. The first electrical signal is configured to stimulate neural activity in the nerve to cause at least one pre-determined physiological response; and the second electrical signal is configured to inhibit neural activity in the nerve to at least partially suppress the least one pre-determined physiological response.

Abstract: A retaining assembly to attach one or more mobile devices to a mobile object. The retaining assembly may include a mounting plate that attaches to the mobile object by way of a mounting bracket or scorecard clip-on. The mounting bracket provides dovetails for selecting engaging the mounting plate in different orientations. The mounting plate facilitates various magnetized components to removably attach to the mobile device. If the mobile device has a third-party extensible grip, a retaining ring may be employed to attach the mobile device or the extensible grip modified to one of the various magnetized components.

Abstract: A retaining assembly to attach one or more mobile devices to a mobile object. The retaining assembly may include a mounting plate that attaches to the mobile object by way of a mounting bracket or scorecard clip-on. The mounting bracket provides dovetails for selecting engaging the mounting plate in different orientations. The mounting plate facilitates various magnetized components to removably attach to the mobile device. If the mobile device has a third-party extensible grip, a retaining ring may be employed to attach the mobile device or the extensible grip modified to one of the various magnetized components.

Abstract: A storage assembly includes top and bottom walls, a pair of end walls extending between the top and bottom walls and cooperating with the top and bottom walls to define an interior space, and at least one end surface configured to closely interfit with at least one end surface of an adjacent storage assembly that is substantially similar to the storage assembly at a predefined angular orientation such that a longitudinal axis of the storage assembly is angularly offset from a longitudinal axis of the adjacent storage assembly when the at least one end surface of the storage assembly is interfit with the at least one surface of the adjacent storage assembly The storage assembly may also include a pair of interior walls and a handle relief extending into the top wall and/or a frame assembly located between one of the end walls and one of the interior walls.

Abstract: A retaining assembly to attach one or more mobile devices to a mobile object. The retaining assembly may include a mounting plate that attaches to the mobile object by way of a mounting bracket or scorecard clip-on. The mounting bracket provides dovetails for selecting engaging the mounting plate in different orientations. The mounting plate facilitates various magnetized components to removably attach to the mobile device. If the mobile device has a third-party extensible grip, a retaining ring may be employed to attach the mobile device or the extensible grip modified to one of the various magnetized components.

Abstract: A fully automated fabrication method and system utilizing a single additive manufacturing platform to fabricate solar cell panels without human-touch labor. The system includes a computer and a robotic arm having a machine vision device and a tool changer to which tools are releasably secured. In an exemplary embodiment, the fabrication method uses pre-fabricated substrates wherein the computer controls the robotic arm to deposit an adhesive layer on a pre-fabricated substrate and thereafter place solar cells on the adhesive layer. The solar cells become bonded to the substrate when the adhesive layer cures. The computer then controls the robotic arm to print electrical connections and electrical bus bars on the substrate with electrically conductive ink in order to electrically connect the solar cells. After the electrically conductive ink cures, the computer controls the robotic arm to spray an encapsulating material over the solar cells and substrate.

Abstract: Processes for inhibiting scale produced during wet process phosphoric acid production by adding a scale inhibiting amount of a reagent having at least one amine portion including at least one primary amine, and at least one hydrocarbyl portion having an insolubilizing group attached thereto to at least one stage of a wet process phosphoric acid production process are provided herein.

Abstract: Oral sorbent compositions that bind small and charged toxins and methods of use.

Abstract: The invention provides devices and methods that can prevent or ameliorate bronchoconstriction. In particular, the invention provides devices and methods in which a signal is delivered to the vagus nerve or the pulmonary branches of the vagus nerves. The signal is able to treat bronchoconstriction and prevent and/or ameliorate bronchoconstriction.

Abstract: The invention provides devices and methods that can prevent or ameliorate bronchoconstriction. In particular, the invention provides devices and methods in which a signal is delivered to the vagus nerve or the pulmonary branches of the vagus nerves. The signal is able to treat bronchoconstriction and prevent and/or ameliorate bronchoconstriction.

Abstract: Processes for inhibiting scale produced during wet process phosphoric acid production by adding a scale-inhibiting amount of a reagent having a primary amine-containing polymer to at least one stage of a wet process phosphoric acid production process are provided herein, wherein said primary amine-containing polymer includes one or more organic moieties that reduce the polymer's solubility in an aqueous environment as compared to its native form, thereby reducing or preventing scale in the wet process phosphoric acid production process.

Abstract: Oral sorbent compositions that bind small and charged toxins and methods of use.

Abstract: The present invention provides devices and methods that can prevent or ameliorate bronchoconstriction by stimulating neural activity, in contrast to those techniques based on denervation, ablation or blocking of neural activity. Methods and devices according to the invention may act responsively or on demand, can preserve neuronal structure and function and will be associated with minimal collateral side-effects. In particular, the invention provides devices and methods in which a signal is delivered to the vagus nerve, for example the cervical vagus nerve or the pulmonary branch of the vagus nerve, in order to stimulate neural activity in the vagal nerve.

Abstract: Processes for inhibiting scale produced during wet process phosphoric acid production by adding a scale-inhibiting amount of a reagent having a primary amine-containing polymer to at least one stage of a wet process phosphoric acid production process are provided herein, wherein said primary amine-containing polymer includes one or more organic moieties that reduce the polymer's solubility in an aqueous environment as compared to its native form, thereby reducing or preventing scale in the wet process phosphoric acid production process.