Patents by Inventor John A. Carrino
John A. Carrino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9092482Abstract: A fair scheduling system with methodology for fairly scheduling queries for execution by a database management system is disclosed. The techniques involve obtaining computer-executable query jobs and cost estimates to execute the query jobs. For example, the cost estimate can be a number of results the query is expected to return. Based on the cost estimates, the fair scheduling system causes the database management system to execute the query jobs as separately executable sub-query tasks in a round-robin fashion which can decrease latency of low cost queries concurrently executing with high cost queries.Type: GrantFiled: March 14, 2013Date of Patent: July 28, 2015Assignee: Palantir Technologies, Inc.Inventors: Michael Harris, John Carrino, Eric Wong
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Publication number: 20150173703Abstract: An embodiment in accordance with the present invention provides a device and method for a quantitatively calibrated computed tomography scanner. The device includes a gentry configured for receiving a patient or part of a patient. The gentry includes an X-ray source and a detector positioned opposite said X-ray source, such that said detector receives the X-rays emitted from the X-ray source. Calibration phantoms are integrated with the gentry and/or a device within the scanner so as to allow for calibration in quantitative CT measurements of Hounsfield units and/or bone mineral density.Type: ApplicationFiled: June 7, 2013Publication date: June 25, 2015Applicant: The Johns Hopkins UniversityInventors: Jeffrey H. Siewerdsen, Abdullah Almuhit, John Carrino
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Patent number: 8945884Abstract: The present invention provides compositions and methods for recombinational cloning. The compositions include vectors having multiple recombination sites and/or multiple topoisomerase recognition sites. The methods permit the simultaneous cloning of two or more different nucleic acid molecules. In some embodiments the molecules are fused together while in other embodiments the molecules are inserted into distinct sites in a vector. The invention also generally provides for linking or joining through recombination a number of molecules and/or compounds (e.g., chemical compounds, drugs, proteins or peptides, lipids, nucleic acids, carbohydrates, etc.) which may be the same or different.Type: GrantFiled: May 13, 2013Date of Patent: February 3, 2015Assignee: Life Technologies CorporationInventors: Jonathan Chesnut, John Carrino, Louis Leong, Knut Madden, Martin Gleeson, James Fan, Michael Brasch, David Cheo, James Hartley, Devon Byrd, Gary Temple
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Publication number: 20130323796Abstract: The present invention provides compositions and methods for recombinational cloning. The compositions include vectors having multiple recombination .sites and/or multiple topoisomerase recognition sites. The methods permit the simultaneous cloning of two or more different nucleic acid molecules. In some embodiments the molecules are fused together while in other embodiments the molecules are inserted into distinct sites in a vector. The invention also generally provides for linking or joining through recombination a .number of molecules and/or compounds (e.g., chemical compounds, drugs, proteins or peptides, lipids, nucleic acids, carbohydrates, etc.) which may be the same or different.Type: ApplicationFiled: May 13, 2013Publication date: December 5, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Jonathan CHESNUT, John Carrino, Louis Leong, Knut Madden, Martin Gleeson, James Fan, Michael Brasch, David Cheo, James Hartley, Devon Byrd, Gary Temple
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Publication number: 20130325666Abstract: Provided herein are collections of matched biological reagents selected from a larger collection of biological reagents, wherein the collection of matched biological reagents relate to a biological element. Also provided are methods for selling an isolated biomolecule or biological research reagent in a collection of matched biological reagents, and methods for selecting an isolated biomolecule or biological research reagent from a collection of biological reagents.Type: ApplicationFiled: March 16, 2012Publication date: December 5, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: John CARRINO, Feng Liang, Siamak Baharloo, Barry I. Schweitzer
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Patent number: 8514229Abstract: Processes, machines, and computer-readable media are provided for expanding and simplifying a polygon or reducing and simplifying a polygon. Polygon expanding or reducing logic receives information that represents a polygon having a set of vertices. The polygon expanding or reducing logic determines another polygon having another set of vertices, such that the other polygon encompasses or is encompassed by the polygon, by determining, for each vertex of the set of vertices, a new set of vertices that are derived from the vertex and are at least a particular distance outside or inside the polygon. The vertex reducing logic determines whether an intermediate vertex is within the particular distance of a proposed segment between two other vertices of the other set of vertices, even though the intermediate vertex is not on the proposed segment, and, if so, removing the intermediate vertex from the other set of vertices.Type: GrantFiled: December 12, 2012Date of Patent: August 20, 2013Assignee: Palantir Technologies, Inc.Inventors: Daniel P. Cervelli, John A. Carrino
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Patent number: 8508533Abstract: Processes, machines, and computer-readable media are provided for expanding and simplifying a polygon or reducing and simplifying a polygon. Polygon expanding or reducing logic receives information that represents a polygon having a set of vertices. The polygon expanding or reducing logic determines another polygon having another set of vertices, such that the other polygon encompasses or is encompassed by the polygon, by determining, for each vertex of the set of vertices, a new set of vertices that are derived from the vertex and are at least a particular distance outside or inside the polygon. The vertex reducing logic determines whether an intermediate vertex is within the particular distance of a proposed segment between two other vertices of the other set of vertices, even though the intermediate vertex is not on the proposed segment, and, if so, removing the intermediate vertex from the other set of vertices.Type: GrantFiled: September 28, 2011Date of Patent: August 13, 2013Assignee: Palantir Technologies, Inc.Inventors: Daniel P. Cervelli, John A. Carrino
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Patent number: 8433702Abstract: Values that occur above a threshold frequency for certain characteristic(s) of a data set are identified. A limited number of count buckets are allocated based on the threshold. Buckets store proxy counts for identifying candidate sets of values rather than actual counts. The data set is divided and each portion is analyzed separately, by iterating through each item in that portion. During each iteration, depending on an item's value(s), a bucket is incremented, all buckets are decremented, or a bucket is assigned or reassigned to count different value(s). A candidate set of values and associated counts is selected for a portion based on the buckets. The candidate sets for each portion are merged and, in some embodiments, filtered based on the associated counts. Actual frequencies are then determined for the values that remain in the merged candidate set.Type: GrantFiled: September 28, 2011Date of Patent: April 30, 2013Assignee: Palantir Technologies, Inc.Inventors: John A. Carrino, Michael Harris
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Publication number: 20130076732Abstract: Processes, machines, and computer-readable media are provided for expanding and simplifying a polygon or reducing and simplifying a polygon. Polygon expanding or reducing logic receives information that represents a polygon having a set of vertices. The polygon expanding or reducing logic determines another polygon having another set of vertices, such that the other polygon encompasses or is encompassed by the polygon, by determining, for each vertex of the set of vertices, a new set of vertices that are derived from the vertex and are at least a particular distance outside or inside the polygon. The vertex reducing logic determines whether an intermediate vertex is within the particular distance of a proposed segment between two other vertices of the other set of vertices, even though the intermediate vertex is not on the proposed segment, and, if so, removing the intermediate vertex from the other set of vertices.Type: ApplicationFiled: September 28, 2011Publication date: March 28, 2013Applicant: Clearwater International, LLCInventors: Daniel P. Cervelli, John A. Carrino
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Publication number: 20130004996Abstract: The present invention provides compositions and methods for recombinational cloning. The compositions include vectors having multiple recombination sites and/or multiple topoisomerase recognition sites. The methods permit the simultaneous cloning of two or more different nucleic acid molecules. In some embodiments the molecules are fused together while in other embodiments the molecules are inserted into distinct sites in a vector. The invention also generally provides for linking or joining through recombination a number of molecules and/or compounds (e.g., chemical compounds, drugs, proteins or peptides, lipids, nucleic acids, carbohydrates, etc.) which may be the same or different.Type: ApplicationFiled: August 26, 2011Publication date: January 3, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Jonathan D. CHESNUT, John Carrino, Louis Leong, Knut Madden, Martin A. G. Gleeson, James Fan, Michael A. Brasch, David Cheo, James L. Hartley, Devon R.N. Byrd, Gary F. Temple
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Patent number: 8207318Abstract: A method of generating a double stranded (ds) recombinant nucleic acid molecule covalently linked in both strands by contacting two or more ds nucleotide sequences with a topoisomerase under conditions such that both termini of at least one end of a first ds nucleotide sequence are covalently linked by the topoisomerase to both termini of at least one end of a second ds nucleotide sequence is provided. Also provided is a method for generating a ds recombinant nucleic acid molecule covalently linked in one strand, by contacting two or more ds nucleotide sequences with a type IA topoisomerase under conditions such that one strand, but not both strands, of one or both ends of a first ds nucleotide sequence are covalently linked by the topoisomerase. Compositions for performing such methods, and compositions generated from such methods also are provided, as are kits containing components useful for conveniently practicing the methods.Type: GrantFiled: April 30, 2008Date of Patent: June 26, 2012Assignee: Life Technologies CorporationInventors: James Fan, John Carrino, Jonathan Chesnut, Knut Madden, Martin Gleeson, Robert Bennett
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Patent number: 8030066Abstract: The present invention provides compositions and methods for recombinational cloning. The compositions include vectors having multiple recombination sites and/or multiple topoisomerase recognition sites. The methods permit the simultaneous cloning of two or more different nucleic acid molecules. In some embodiments the molecules are fused together while in other embodiments the molecules are inserted into distinct sites in a vector. The invention also generally provides for linking or joining through recombination a number of molecules and/or compounds (e.g., chemical compounds, drugs, proteins or peptides, lipids, nucleic acids, carbohydrates, etc.) which may be the same or different.Type: GrantFiled: December 18, 2006Date of Patent: October 4, 2011Assignee: Life Technologies CorporationInventors: Jonathan D. Chesnut, John Carrino, Louis Leong, Knut Madden, Martin Gleeson, James Fan, Michael Brasch, David Cheo, James L. Hartley, Devon R. Byrd, Gray F. Temple
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Publication number: 20110166868Abstract: Subscription-based systems and methods where a provider provides one or more customers, identified as subscribers or non-subscribers, with research products and services (e.g., for industries involved in genomic and proteomic research). Initially, the provider prepares collections of clones and provides customers with access to clone collections. Individual clones in a clone collection may comprise an ORF that may be flanked by recombination sites. Further, an ORF may contain a suppressible stop codon that may be suppressed to produce a fusion protein comprising the ORF and a tag sequence. Provider may provide additional related services and/or products. The products and services offered to the customers will vary depending on their designation as either subscribers or non-subscribers.Type: ApplicationFiled: March 1, 2010Publication date: July 7, 2011Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Lincoln Muir, August Sick, Nancy Groot, Dwayne W. Dexter, Charles Robinson, John Carrino, Robert Bennett
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Publication number: 20090326208Abstract: A method of generating a double stranded (ds) recombinant nucleic acid molecule covalently linked in both strands by contacting two or more ds nucleotide sequences with a topoisomerase under conditions such that both termini of at least one end of a first ds nucleotide sequence are covalently linked by the topoisomerase to both termini of at least one end of a second ds nucleotide sequence is provided. Also provided is a method for generating a ds recombinant nucleic acid molecule covalently linked in one strand, by contacting two or more ds nucleotide sequences with a type IA topoisomerase under conditions such that one strand, but not both strands, of one or both ends of a first ds nucleotide sequence are covalently linked by the topoisomerase. Compositions for performing such methods, and compositions generated from such methods also are provided, as are kits containing components useful for conveniently practicing the methods.Type: ApplicationFiled: April 30, 2008Publication date: December 31, 2009Applicant: INVITROGEN CORPORATIONInventors: John Carrino, James Fan, Robert P. Bennett, Jonathan D. Chesnut, Martin A. Gleeson, Knut R. Madden
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Publication number: 20080241889Abstract: The present invention provides compositions and methods for recombinational cloning. The compositions include vectors having multiple recombination sites and/or multiple topoisomerase recognition sites. The methods permit the simultaneous cloning of two or more different nucleic acid molecules. In some embodiments the molecules are fused together while in other embodiments the molecules are inserted into distinct sites in a vector. The invention also generally provides for linking or joining through recombination a number of molecules and/or compounds (e.g., chemical compounds, drugs, proteins or peptides, lipids, nucleic acids, carbohydrates, etc.) which may be the same or different.Type: ApplicationFiled: December 18, 2006Publication date: October 2, 2008Applicant: INVITROGEN CORPORATIONInventors: Jonathan D. Chesnut, John Carrino, Louis Leong, Knut Madden, Martin A.G. Gleeson, James Fan, Michael A. Brasch, David Cheo, James L. Hartley, Devon R.N. Byrd, Gray F. Temple
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Patent number: 7301450Abstract: A versatile Citizen Alert System is connected to Internet and private databases to acquire real time information useful for subscribed users. During registration, users are required to provide multimedia contact information, including telephone numbers, cell phone numbers, pager information, Blackberry or PDA information, e-mail address, and physical address, along with user defined sensitivities to alerts, including sensitivities to natural emergencies, man made emergencies and professional requirements. The system has a local or remote administrator that constantly analyzes the acquired data in accordance with requirements of each and every user, orders the data to generate alert information specific to a user, and communicates the alert to each and every user using multiple delivery platforms. A user specific, secured web page providing details of alert and hyperlinks constitutes an additional information source.Type: GrantFiled: March 14, 2006Date of Patent: November 27, 2007Inventor: John Carrino
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Publication number: 20070216535Abstract: A versatile Citizen Alert System is connected to Internet and private databases to acquire real time information useful for subscribed users. During registration, users are required to provide multimedia contact information, including telephone numbers, cell phone numbers, pager information, Blackberry or PDA information, e-mail address, and physical address, along with user defined sensitivities to alerts, including sensitivities to natural emergencies, man made emergencies and professional requirements. The system has a local or remote administrator that constantly analyzes the acquired data in accordance with requirements of each and every user, orders the data to generate alert information specific to a user, and communicates the alert to each and every user using multiple delivery platforms. A user specific, secured web page providing details of alert and hyperlinks constitutes an additional information source.Type: ApplicationFiled: March 14, 2006Publication date: September 20, 2007Inventor: John Carrino
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Publication number: 20070196838Abstract: The present invention provides compositions and methods for recombinational cloning. The compositions vectors having multiple recombination sites and/or multiple topoisomerase recognition sities. The methods premit the simultaeous cloning of two or more different nucleic acid molecules. In some embodiments the molecules are fused together while in other embodiments the molecules are inserted into distinct sites in a vector. The invention also generally provides for linking or joining through recombination a number of molecules and/or compounds (e.g., chemical compounds, drugs, proteins or peptides, lipids, nucleic acids, carbohydrates, etc.) which may be the same or different.Type: ApplicationFiled: December 19, 2006Publication date: August 23, 2007Applicant: INVITROGEN CORPORATIONInventors: Jonathan Chesnut, John Carrino, Louis Leong, Knut Madden, Martin Gleeson, James Fan, Michael Brasch, David Cheo, James Hartley, Devon Byrd, Gray Temple
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Patent number: 7244560Abstract: The present invention provides compositions and methods for recombinational cloning. The compositions include vectors having multiple recombination sites and/or multiple topoisomerase recognition sites. The methods permit the simultaneous cloning of two or more different nucleic acid molecules. In some embodiments the molecules are fused together while in other embodiments the molecules are inserted into distinct sites in a vector. The invention also generally provides for linking or joining through recombination a number of molecules and/or compounds (e.g., chemical compounds, drugs, proteins or peptides, lipids, nucleic acids, carbohydrates, etc.) which may be the same or different.Type: GrantFiled: December 7, 2001Date of Patent: July 17, 2007Assignee: Invitrogen CorporationInventors: Jonathan D. Chestnut, John Carrino, Louis Leong, Knut Madden, Martin Gleeson, James Fan, Michael A. Brasch, David Cheo, James L. Hartley, Devon R.N. Byrd, Gary F. Temple
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Patent number: 7198924Abstract: The present invention provides compositions and methods for recombinational cloning. The compositions include vectors having multiple recombination sites and/or multiple topoisomerase recognition sites. The methods permit the simultaneous cloning of two or more different nucleic acid molecules. In some embodiments the molecules are fused together while in other embodiments the molecules are inserted into distinct sites in a vector. The invention also generally provides for linking or joining through recombination a number of molecules and/or compounds (e.g., chemical compounds, drugs, proteins or peptides, lipids, nucleic acids, carbohydrates, etc.) which may be the same or different.Type: GrantFiled: March 4, 2004Date of Patent: April 3, 2007Assignee: Invitrogen CorporationInventors: Jonathan D. Chesnut, John Carrino, Louis Leong, Knut Madden, Martin A. G. Gleeson, James Fan, Michael A. Brasch, David Cheo, James L. Hartley, Devon R. N. Byrd, Gary F. Temple