Abstract: A control system an unmanned vehicle includes a first processing unit configured to execute a primary autopilot process for controlling the unmanned vehicle. The control system further includes a programmable logic array in operative communication with the first processing unit. The control system also includes a state machine configured in the programmable logic array. The state machine is configured to enable control of the unmanned vehicle according to a backup autopilot process in response to an invalid output of the first processing unit.

Abstract: This invention relates to compounds of Formula (I): and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein L1, L2, R1, R2, R3 and n are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.

Abstract: The disclosure relates to methods of treating and/or preventing scarring that would otherwise result from an incision to an area of skin. The methods comprise administering a composition comprising tropoelastin to an area of skin that is to receive an incision and/or after the incision. It is also contemplated that the compositions may reduce scar discoloration. Methods of preventing or reducing keloid re-occurrence are also provided.

Abstract: A mesh wireless access point (WAP) includes a housing, a first radio assembly, a second radio assembly, and an internal communication link between the first and second radio assemblies. The housing is configured to be affixed to, or integrated with, a feature of a building. The first radio assembly is incorporated with the housing and configured to support a first wireless communication link, and the second radio assembly is incorporated with the housing and configured to support a second wireless communication link. The internal communication link is configured to transfer data packets between the first and second radio assemblies.

Abstract: A materialization configuration request is received via a programmatic interface from a client of a journal-based multi-data-store database. The request indicates a partitioning rule to be used to select, for respective writes indicated in committed transaction entries of a journal, the materialization node at which the writes are to be stored. A control plane component of the database verifies that a set of materialization nodes corresponding to the partitioning rule has been established, and initiates the propagation of writes from the journal to the materialization nodes by respective write appliers.

Abstract: One variation of a system includes: a substrate including an aperture and a multi-layer inductor; and a cover layer arranged over the substrate and cooperating with the aperture to define a housing. Additionally, the system includes a fingerprint reader arranged within the housing and configured to permeate through the cover layer to scan a fingerprint applied over the cover layer. A magnetic element is arranged facing the multi-layer inductor and configured to inductively couple the multi-layer inductor. The system further includes a controller configured to: read electrical values from the multi-layer inductor; and register a fingerprint input on the cover layer based on the electrical values. Additionally, the controller can: read fingerprint values from the fingerprint reader to generate a fingerprint image; and trigger a first oscillating voltage across the multi-layer inductor to oscillate the cover layer in response to the fingerprint image deviating from a target fingerprint image.

Abstract: Provided are a storage device, system, and method for throttling host writes in a host buffer to a storage device. The storage device is coupled to a host system having a host buffer that includes reads and writes to pages of the storage device. Garbage collection consolidates valid data from pages in the storage device to fewer pages. A determination is made as to whether a processing measurement at the storage device satisfies a threshold. A timer value is set to a positive value in response to determining that the processing measurement satisfies the threshold. The timer is started to run for the timer value. Writes from the host buffer are blocked while the timer is running. Writes remain in the host buffer while the timer is running. A write is accepted from the host buffer to process in response to expiration of the timer.

Abstract: Methods and apparatus for ion accumulation are disclosed. An apparatus for ion accumulation includes multiple regions. A first region receives and transfers ions to a second region using a first drive potential. The second region is switchable between a first state where it generates a first electric field preventing ions from further movement and entering a third region, and a second state where it generates a second electric field that guides the ions toward the third region. When in the first state, the ions are prevented from further movement by the first electric field, which causes the ions to accumulate in the second region. When in the second state, the ions are moved from the second region to the third region by the second electric field. A method of accumulating ions involves switching an electric field applied to a region between a trap state and a release state.

Abstract: One variation of a method for detecting an input at a touch sensor—including a force-sensitive layer exhibiting variations in local resistance responsive to local variations in applied force on a touch sensor surface and a set of drive and sense electrodes—includes: driving a drive electrode with a drive signal; reading a sense signal from a sense electrode; detecting a alternating-current component and a direct-current component of the sense signal; in response to a magnitude of the direct-current component of the sense signal falling below a threshold magnitude, detecting an input on the touch sensor surface during the scan cycle based on the alternating-current component of the sense signal; and, in response to the magnitude of the direct-current component of the sense signal exceeding the threshold magnitude, detecting the input on the touch sensor surface during the scan cycle based on the direct-current component of the sense signal.

Abstract: An apparatus for ion manipulation having improved duty cycle that includes a pre-filter region and an accumulation region. The pre-filter region is configured to receive ions and perform a first ion mobility filtering operation on the ions to separate the ions into a first group of ions and a second group of ions based on mobility of the ions. The accumulation region is configured to receive the first group of ions from the pre-filter region, accumulate the first group of ions into an ion packet, and release the ion packet into an ion mobility separation region configured separate the ions based on mobility of the ions. Wherein the pre-filter region is configured to reduce the amount of ions provided to the accumulation region and increase the amount of time the accumulation region can accumulate ions.

Abstract: A computer system and method for synchronizing actions associated with media between a media/network device and peripherals. In an example implementation, a system includes a one or more processors configured to receive, by a communication module from a media/network device based on peripheral addressing information, a peripheral payload including a first set of actions and timing information related to media. The one or more processors perform the first set of actions based on the peripheral payload, generate response data for the first set of actions, and transmit the response data to the media/network device via a wireless network.

Abstract: Methods, systems, and apparatus, including medium-encoded computer program products, for computer aided design of physical structures using generative design processes, where three dimensional (3D) models of the physical structures can be produced to include lattices, hollows, holes, and combinations thereof, include: obtaining design criteria for an object; iteratively modifying 3D topology and shape(s) for the object using generative design process(es) that employ a macrostructure representation, e.g., using level-set method(s), in combination with physical simulation(s) that place void(s) in solid region(s) or solid(s) in void region(s) of the generative model of the object; and providing a 3D model of the generative design for the object for use in manufacturing a physical structure corresponding to the object using one or more computer-controlled manufacturing systems.

Abstract: Methods for treating a neuropsychiatric disorder by administering an iboga alkaloid and a cardioprotective agent in conjunction with analysis of brain image data is described. Also described are methods to improve brain health and to slow or reverse brain aging by disorder by administering an iboga alkaloid and a cardioprotective agent, where analysis of brain image data is used to monitor and/or evaluate treatment effectiveness.

Abstract: A light fixture includes a lamp having a light source, a petal mechanism having a plurality of petals moveable between an open position and a closed position, and a petal actuator coupled to the petal mechanism to controllably move the petals of the petal mechanism between the open position and the closed position.

Abstract: A cooking appliance includes an oven body having an interior compartment and a door panel for accessing the interior compartment, wherein the interior compartment is sized to receive a food product; a removable heated tray positionable within the interior compartment, wherein the heated tray includes a top tray surface and a first heating source positioned below the top tray surface; and a second heating source positioned within the interior compartment.

Abstract: The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof; wherein: n is 1 or 2; X is CH or N; Y is selected from CH and C—F; Z is selected from C—Rz and N; R1 is selected from: -(Alk1)t-Cyc1; wherein t is 0 or 1; Optionally substituted C1-6 acyclic hydrocarbon groups R2 is selected from hydrogen; halogen; and C1-3 hydrocarbon groups optionally substituted with one or more fluorine atoms; R3 is hydrogen or a group L1-R7; R4 is selected from hydrogen; methoxy; and optionally substituted C1-3 alkyl; and R4a is selected from hydrogen and a C1-3 alkyl group; wherein Rz, Alk1, Cyc1, L1 and R7 are defined herein; provided that the compound is other than 6-benzyl-3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and 3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and salts and tautomers thereof.

Abstract: A method and bed system for controlling a mattress climate-control system based on a thermal event. The bed system includes a mattress, a mattress climate-control system, a mechanical thermal detector, and a controller. The mattress climate-control system controls a climate at the mattress. The mechanical thermal detector is positioned at the mattress. A condition of the mechanical thermal detector changes in response to a thermal event at the mattress. The controller is connected to the mattress climate-control system. The controller perform operations including detecting the condition of the mechanical thermal detector and operating the mattress climate-control system based on the condition of the mechanical thermal detector.

Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.

Abstract: Aspects of the present disclosure relate generally to methods, compositions, and kits for in situ whole cell or single cell barcoding. Aspects of the present disclosure also include a computer readable-medium and a processor to carry out the steps of the method described herein. In some embodiments, the disclosure relates to whole cell or single cell barcoding performed in situ.

Abstract: A system comprising a storage member and a load cell. The storage member is for storing a product. The load cell measures a force applied to the load cell. At least part of the force applied to the load cell is provided, directly or indirectly, by a weight of the product. The system is configured to determine a quantity of the product based, at least in part, on the force measured by the load cell.