Patents by Inventor John A. DeSimone

John A. DeSimone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7597834
    Abstract: Disclosed, amongst other things, is: (i) a rotary injection molding machine; (ii) a mold; (iii) a mass-drive; and (iv) a method of a molding, amongst other things.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: October 6, 2009
    Assignee: Husky Injection Molding Systems Ltd.
    Inventor: John DeSimone
  • Publication number: 20050031717
    Abstract: The pharmacology of the capsaicin receptor has been discovered to be predictive of the enhancement of the non-specific salt taste channel. Salt taste in a mammal may be modified by introducing to a mammalian taste receptor cell, a non-salty ligand which is a taste modulator. Examples of the ligand include capsaicin; resiniferatoxin (RTX); piperine; 2-(3,4-dimethylbenzyl)-3-{[(4-hydroxy-3-methoxybenzyl)amino]carbothioyl}propyl pivalate (agonist 23); olvanil, capsiate; evodiamine; ethanol; cetylpyridinium chloride; dodecylpyridinium bromide; capsazepin; SB366791, etc. Salt taste thus may be modified by a non-salty ligand. By introducing certain non-salty ligands into the salt transduction process, the cation non-specific salt taste transduction process may be modified.
    Type: Application
    Filed: July 9, 2004
    Publication date: February 10, 2005
    Inventors: John DeSimone, Gerard Heck, Vijay Lyall
  • Patent number: 5519897
    Abstract: The invention provides a portable apparatus having housing structure with a duck-bill shaped gas inlet that is fitted between the top face of a toilet bowl and the underside of the lowered toilet seat, to open directly to air confined within the bowl. Remaining housing structure defines an air flow path to a gas outlet outside of the toilet bowl. A blower and an electric heater in the housing structure air flow operate for withdrawing and then heating the toilet bowl gases before discharging such gases from the outlet back to the ambient air. By heating the gases to temperatures between 450-1000 degrees F., in sufficient volumes to provide between 5-100 turnover of the confined bowl gases per minute, and discharging the treated gases at temperatures in the range of between 150-400 degrees F. back to the ambient air, most defecation odors are eliminated or minimized.
    Type: Grant
    Filed: March 13, 1995
    Date of Patent: May 28, 1996
    Inventor: John DeSimone
  • Patent number: 4997672
    Abstract: This invention relates to processes and compositions found useful for potentiating the taste of sodium chloride in humans. It has been found that the taste of sodium chloride can be enhanced in the human mouth by combining therewith, or with foods or beverages containing same, small quantities of cationic surfactants comprised of certain quaternary ammonium salts. A preferred sodium chloride taste enhancing surfactant is cetyl pyridinium chloride.
    Type: Grant
    Filed: July 25, 1990
    Date of Patent: March 5, 1991
    Assignee: Virginia Commonwealth University
    Inventors: John A. DeSimone, Gerard L. Heck
  • Patent number: 4940056
    Abstract: The invention discloses an electrogustograph for detecting the physiological responses of the tongue to various tastants applied thereto through a small vacuum sensor. The small sensor has a peripheral annual vacuum port by which the sensor is attached to the top surface of the tongue. The annular vacuum port surrounds a cavity which has one port for insertion of the tastant which flows across the surface of a portion of the tongue to a second port which serves as an outlet for the tastant. Electrodes are present in the sensor and on the cheek of the person being tested so as to measure the difference in the flow of electricity across the top surface of the tongue when various tastants are applied to the tongue. The electrogustograph is supported by suitable electronics and fluid flow pumps and valves all under the control of a microcontroller to provide a flexible and relatively easy to use electrogustographic system.
    Type: Grant
    Filed: November 15, 1988
    Date of Patent: July 10, 1990
    Assignee: Center for Innovative Technology
    Inventors: Gerard L. Heck, John A. DeSimone