Abstract: A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.

Abstract: Pressure regulators with adjustable boost bodies are described herein. An example pressure regulator includes a valve body; a seat in the fluid passageway; an actuator casing coupled to the valve body; and a plug assembly including: a stem; a plug coupled to the stem; a stem guide disposed in the channel of the actuator casing; a boost body on the second side of the stem guide; and a tube extending through the boost body, the tube and the boost body forming a unitary structure to prevent movement of the tube relative to the boost body, the tube having a first end and a second end, the second end disposed in a downstream location relative to the seat, wherein the boost body is rotatable with respect to the stem guide to position the tube in at least one other orientation relative to the actuator casing.

Abstract: A tether tensioner includes a handle assembly, an elongate member extending distally from the handle assembly, and an engaging portion. The handle assembly includes a stationary member, a trigger pivotably coupled to the stationary member, and a spool rotatably supported on the stationary member. The spool is configured to wrap a tether thereabout. The spool is operatively coupled with the trigger such that pivoting of the trigger relative to the stationary member causes rotation of the spool. The elongate member includes a channel configured to slidably receive a tether therethrough. The engaging portion is configured to receive a head portion of a bone screw such that a tether extends from the head portion disposed in the engaging portion to the spool through the channel of the elongate member.

Abstract: Breathable residual-limb system that admits air and allows sweat to evaporate from the surface of the residual limb. In an embodiment, the system comprises a liner sock to be worn on the residual limb, and comprising air-permeable textile forming a substantially cylindrical portion that is closed on a distal end and open on a proximal end and comprising an internal surface and an external surface. The liner sock further comprises a friction-interface material that covers only a portion of the internal surface of the air-permeable textile, such that, when worn on the residual limb, the friction-interface material contacts a surface of the residual limb, and an uncovered portion of the air-permeable textile which the friction-interface material does not cover allows air to pass between an external environment of the liner sock and the surface of the residual limb.

Abstract: The present invention provides RAD51 inhibitors having the structural formula (I): or a pharmaceutically acceptable salt or solvate thereof. Also provided are methods of treating or preventing cancer comprising administration of the compounds of the present invention, as well as uses of the compounds to induce a synergistic effect with known chemotherapeutic.

Abstract: A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.

Abstract: A syringe or other vessel having a substrate surface coated by PECVD is provided. The PECVD coating is made by generating plasma from a gaseous reactant comprising an organosilicon precursor and optionally O2. The lubricity, hydrophobicity and/or barrier properties of the coating are set by setting the ratio of the O2 to the organosilicon precursor in the gaseous reactant, and/or by setting the electric power used for generating the plasma. In particular, a lubricity coating made by said method is provided. Vessels coated by said method and the use of such vessels protecting a compound or composition contained or received in said coated vessel against mechanical and/or chemical effects of the surface of the uncoated vessel material are also provided.

Abstract: A computing device and method of controlling access to a computing device. An application to be used when the computing device is in a locked state is selected, wherein in the locked state, only use of the selected application is permitted. The computing device enters the locked state. Use of the selected application without unlocking the computing device is allowed.

Abstract: Methods for determining desired doping conditions for a semiconducting single-walled carbon nanotube (s-SWCNT) are provided. One exemplary method includes doping each of a plurality of s-SWCNT networks under a respective set of doping conditions; determining a thermoelectric (TE) power factor as a function of a fractional bleach of an absorption spectrum for the plurality of s-SWCNT networks doped under the respective sets of doping conditions; and using the function to identify one of the TE power factors within a range of the fractional bleach of the absorption spectrum. The identified TE power factor corresponds to the desired doping conditions.

Abstract: The present disclosure relates to a composition that includes a film having a network of randomly aligned carbon nanotubes, where the carbon nanotubes have an average diameter between about 0.6 nm and about 2.0 nm and the carbon nanotubes form bundles having an average diameter between about 3 nm and about 50 nm. In addition, the composition is characterized by a power factor ?2? between 1 ?W/mK2 and about 3500 ?W/mK2 and by ZT=?2?T/k between about 0.02 and about 2.0 over a temperature range between about 100 K and about 500 K.

Abstract: A spinal fixation construct for aligning vertebral bodies includes a bone screw, a spinal rod, a flexible member, and a fixation member. The spinal rod is disposed within a saddle portion of a housing of the bone screw, and includes an elongated body having a first end and a second end. The spinal rod is formed from a first material having a first modulus of elasticity. The flexible member is coupled to the spinal rod, and includes an elongated body having a first end portion and a second end portion. The flexible member is formed from a second material having a second modulus of elasticity that is different from the first modulus of elasticity. The fixation member includes a threaded body portion and a head portion defining a hole therethrough. A portion of the flexible member extends through the hole of the head portion.

Abstract: A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.

Abstract: A spinal fixation construct for aligning vertebral bodies includes a bone screw, a spinal rod, a flexible member, and a fixation member. The spinal rod is disposed within a saddle portion of a housing of the bone screw, and includes an elongated body having a first end and a second end. The spinal rod is formed from a first material having a first modulus of elasticity. The flexible member is coupled to the spinal rod, and includes an elongated body having a first end portion and a second end portion. The flexible member is formed from a second material having a second modulus of elasticity that is different from the first modulus of elasticity. The fixation member includes a threaded body portion and a head portion defining a hole therethrough. A portion of the flexible member extends through the hole of the head portion.

Abstract: Breathable residual-limb system that admits air and allows sweat to evaporate from the surface of the residual limb. In an embodiment, the system comprises a liner sock to be worn on the residual limb, and comprising air-permeable textile forming a substantially cylindrical portion that is closed on a distal end and open on a proximal end and comprising an internal surface and an external surface. The liner sock further comprises a friction-interface material that covers only a portion of the internal surface of the air-permeable textile, such that, when worn on the residual limb, the friction-interface material contacts a surface of the residual limb, and an uncovered portion of the air-permeable textile which the friction-interface material does not cover allows air to pass between an external environment of the liner sock and the surface of the residual limb.

Abstract: A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.

Abstract: A syringe or other vessel having a substrate surface coated by PECVD is provided. The PECVD coating is made by generating plasma from a gaseous reactant comprising an organosilicon precursor and optionally O2. The lubricity, hydrophobicity and/or barrier properties of the coating are set by setting the ratio of the O2 to the organosilicon precursor in the gaseous reactant, and/or by setting the electric power used for generating the plasma. In particular, a lubricity coating made by said method is provided. Vessels coated by said method and the use of such vessels protecting a compound or composition contained or received in said coated vessel against mechanical and/or chemical effects of the surface of the uncoated vessel material are also provided.

Abstract: Disclosed herein are devices, systems, and methods for measuring socket fit in lower limb prostheses and detecting motion of a residual limb relative to a prosthetic socket. Also disclosed herein are methods for developing a socket-fit detection system for sock management that can be applied to adjustable socket systems.

Abstract: A coral reef float utilizes a large, elongated steel and, optimally, balloon shaped structures which can be prefabricated en masse, anchored in place to rest buoyant below the ocean surface, and then used to farm live coral. These large structures using biorock applications have insulated copper cables attached at multiple points every 5-10 feet along the structure for homogenous corrosion resistance and mineral accretion on the surface of the structure. A hollow, balloon shaped structure allows more of this copper wiring to be connected internally, where it can be protected from corrosion. Helical anchors can be used in soft sediments and to handle extreme conditions for tethered floats using easy-to-deploy systems onboard ships. Buoyant artificial reefs will be able to be positioned where other artificial reefs cannot effectively be placed.

Abstract: Electronic ratchet devices comprising a pair of first and second electrodes; a dielectric layer; a gate electrode layer; and a transport layer are disclosed herein.

Abstract: Disclosed herein are devices, systems, and methods for measuring socket fit in lower limb prostheses and detecting motion of a residual limb relative to a prosthetic socket. Also disclosed herein are methods for developing a socket-fit detection system for sock management that can be applied to adjustable socket systems.