Abstract: A parametric constant resolves to different values in different contexts, but a single value within a particular context. An anchor constant is a parametric constant that allows for a degree of parametricity for an API point. The context for the anchor constant is provided by a caller to the API point. The anchor constant resolves to an anchor value that records specialization decisions for the API point within the provided context. Specialization decisions may include type restrictions, memory layout, and/or memory size. The anchor value together with an unspecialized type of the API point result in a specialized type of the API point. A class object representing the specialized type is created. The class object may be accessible to the caller, but the full value of the anchor value is not accessible to the caller. The API point is executed based on the specialization decisions embodied in the anchor value.

Abstract: A type restriction contextually modifies an existing type descriptor. The type restriction is imposed on a data structure to restrict the values that are assumable by the data structure. The type restriction does not cancel or otherwise override the effect of the existing type descriptor on the data structure. Rather the type restriction may declare that a value of the data structure's type is forbidden for the data structure. Additionally or alternatively, the type restriction may declare that an element count allowable for a data structure's type is forbidden for the data structure. Type restriction allows optionality (where only a singleton value for a data structure is allowed), empty sets (where no value for a data structure is allowed), and multiplicity (where only a limited element count for a data structure) to be injected into a code set independent of data type. Type restriction allows certain optimizations to be performed.

Abstract: A parametric constant resolves to different values in different contexts, but a single value within a particular context. An anchor constant is a parametric constant that allows for a degree of parametricity for an API point. The context for the anchor constant is provided by a caller to the API point. The anchor constant resolves to an anchor value that records specialization decisions for the API point within the provided context. Specialization decisions may include type restrictions, memory layout, and/or memory size. The anchor value together with an unspecialized type of the API point result in a specialized type of the API point. A class object representing the specialized type is created. The class object may be accessible to the caller, but the full value of the anchor value is not accessible to the caller. The API point is executed based on the specialization decisions embodied in the anchor value.

Abstract: An antenna array is provided having multiple antenna elements mountable to the roof of a locomotive. Each of the antenna elements has a separate signal path of one or more conductive elements in a housing and shares a common hole or opening to outside the housing through which the signal path of each antenna element is extendable. The signal path of each antenna element then extends via a common access hole in the roof of the locomotive for enabling one or more of passage of signals to or from the antenna element. The access hole is below the array when the common hole is along the bottom of the housing, and elsewhere along the roof when the common hole is along a side of the housing. Two of the antenna arrays may be mounted in a parallel relationship spaced from each other along the locomotive roof and share the same or a different access hole in such roof.

Abstract: An antenna array is provided having multiple antenna elements mountable to the roof of a locomotive. Each of the antenna elements has a separate signal path of one or more conductive elements in a housing and shares a common hole or opening to outside the housing through which the signal path of each antenna element is extendable. The signal path of each antenna element then extends via a common access hole in the roof of the locomotive for enabling one or more of passage of signals to or from the antenna element. The access hole is below the array when the common hole is along the bottom of the housing, and elsewhere along the roof when the common hole is along a side of the housing. Two of the antenna arrays may be mounted in a parallel relationship spaced from each other along the locomotive roof and share the same or a different access hole in such roof.

Abstract: An antenna array is provided having multiple antenna elements mountable to the roof of a locomotive. Each of the antenna elements has a separate signal path of one or more conductive elements in a housing and shares a common hole or opening to outside the housing through which the signal path of each antenna element is extendable. The signal path of each antenna element then extends via a common access hole in the roof of the locomotive for enabling one or more of passage of signals to or from the antenna element. The access hole is below the array when the common hole is along the bottom of the housing, and elsewhere along the roof when the common hole is along a side of the housing. Two of the antenna arrays may be mounted in a parallel relationship spaced from each other along the locomotive roof and share the same or a different access hole in such roof.

Abstract: A tri-band antenna (10) is provided having a pair of antenna elements (12, 14), in which the first antenna element (14) operates in a first UHF frequency band, and the second antenna element (12) operates in a second VHF band and a third cellular frequency band. The bottom end (12a, 14a) of each of the antenna elements (12, 14) is fixed into a first member (16) from which the antenna elements extend parallel and spaced apart from each other to their different respective heights. A second member (13) couples the antenna elements (12, 14) to each other at a distance from the first member (16) to adjust the operation of the tri-band antenna (10) in at least the UHF band. A base member (19) is provided for mounting the tri-band antenna (10) along a surface of a vehicle. A signal feed member (20) extends through the base member (19) and has one end (20a) attached to the first member (16) and another end (20b) providing a RF connector.

Abstract: A tri-band antenna is provided having a pair of antenna elements, in which the first antenna element operates in a UHF band, and the second antenna element operates in VHF and cellular bands. The antenna elements are fixed into a first member from which the antenna elements extend parallel and spaced apart from each other to their different respective heights. A second member couples the antenna elements to each other at a distance from the first member to adjust at least the UHF band. A base member is provided for mounting the tri-band antenna on a vehicle. A signal feed member extends through the base member and has one end attached to the first member and another end providing a RF connector. The signal feed member provides the antennal elements, via the first member, with a common signal path for transmission and reception of RF signals in all three bands.

Abstract: The present invention relates to the constitutive activity of the Hedgehog pathway in non-small cell lung carcinoma (NSCLC). A method for diagnosing NSCLC by detecting the level of a component of the Hedgehog pathway is provided, as is a method for identifying subjects that will respond positively to treatment with a Hedgehog pathway antagonist. Methods for treating subjects with cancer or cancers resistant to Hedgehog pathway antagonists are also provided.

Abstract: A method of analyzing O-linked oligosaccharides in a sample is disclosed. The method comprises the steps of digesting a glycoprotein with a proteolytic enzyme, performing solid-phase permethylation of the oligosaccharide, then analyzing the permethylated and non-reduced O-linked oligosaccharides using MALDI-TOF mass spectrometry.

Abstract: The present invention relates to the constitutive activity of the Hedgehog pathway in non-small cell lung carcinoma (NSCLC). A method for diagnosing NSCLC by detecting the level of a component of the Hedgehog pathway is provided, as is a method for identifying subjects that will respond positively to treatment with a Hedgehog pathway antagonist. Methods for treating subjects with cancer or cancers resistant to Hedgehog pathway antagonists are also provided.

Abstract: The present invention relates to abrasive composites having improved abrasive particle retention due to unique coating designs. The present invention describes coated abrasive particles having tortuous surface topography, a process for producing such coated abrasive particles, and products comprising such coated abrasive particles. The coated abrasive particles have an outer layer coating with highly tortuous surface comprising about 5 spikes and have a tortuosity of at least about 1.1. The coated abrasive particles may be used in composites including metal/metal alloy matrix composites, ceramic/glass matrix composites, and polymer based matrix composites.

Abstract: The present invention relates to the use of sonic hedgehog antagonists in the prevention and treatment of cancer and other hyperproliferative diseases or disorders. Methods for identifying such antagonists are also provided.

Abstract: A method for preparing coated diamond particles comprising the steps of coating the diamond particles with nickel in the presence of a reducing agent having a pH ranging of from about 6 to 10, and recovering the diamond particles coated with nickel/boron (Ni/B) wherein the Ni/B coating contains less than about 5 wt-% boron content. Coated diamond particles are used in abrasive tools/cutting elements such as grinding wheels, saw segments, drill bits and the like.

Abstract: Isolated native forms of soluble, freely diffusible Sonic hedgehog protein and recombinant forms of soluble, freely diffusible oligomeric Sonic hedgehog protein are produced. Methods of assaying an oligomeric Sonic hedgehog protein derived from a tissue and/or cell comprise measuring a conditioned media to detect the production of the soluble, freely diffusible Sonic hedgehog protein.