Patents by Inventor John A. Hey

John A. Hey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220096406
    Abstract: Disclosed herein are methods for treating, ameliorating, and/or preventing Alzheimer's Disease in a specific patient population using tramiprosate, valyl-3-amino-1-propanesulfonic acid, or a pharmaceutically acceptable salt thereof based upon a combination of APOE4 status and disease severity.
    Type: Application
    Filed: September 17, 2021
    Publication date: March 31, 2022
    Inventors: Susan ABUSHAKRA, Aidan POWER, Martin TOLAR, John HEY, Jeremy YU, Petr KOCIS
  • Publication number: 20220087967
    Abstract: Provided herein is the use of a compound of Formula (I) or a pharmaceutically acceptable salt thereof, for treating a disease characterized by amyloid and amyloid-like aggregates, e.g., Alzheimer's disease.
    Type: Application
    Filed: July 30, 2019
    Publication date: March 24, 2022
    Inventors: Petr Kocis, John Hey, Martin Tolar
  • Publication number: 20220062241
    Abstract: Methods of treating a disease characterized by amyloid aggregates are provided herein.
    Type: Application
    Filed: June 25, 2021
    Publication date: March 3, 2022
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Patent number: 11191742
    Abstract: Disclosed herein are methods for treating, ameliorating, and/or preventing Alzheimer's Disease in a specific patient population using tramiprosate, valyl-3-amino-1-propanesulfonic acid, or a pharmaceutically acceptable salt thereof based upon a combination of APOE4 status and disease severity.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: December 7, 2021
    Assignee: Alzheon, Inc.
    Inventors: Susan Abushakra, Aidan Power, Martin Tolar, John Hey, Jeremy Yu, Petr Kocis
  • Publication number: 20210315847
    Abstract: Tramiprosate and derivatives thereof are provided herein for treating neurodegenerative disorders such as Alzheimer's disease (AD).
    Type: Application
    Filed: July 30, 2019
    Publication date: October 14, 2021
    Inventors: John Hey, Petr Kocis, Martin Tolar, Neil William Flanzraich
  • Patent number: 11077095
    Abstract: Methods of treating a disease characterized by amyloid aggregates are provided herein.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: August 3, 2021
    Assignee: Alzheon, Inc.
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Patent number: 11053192
    Abstract: Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: July 6, 2021
    Assignee: Alzheon, Inc.
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Publication number: 20200347012
    Abstract: Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.
    Type: Application
    Filed: March 3, 2020
    Publication date: November 5, 2020
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Publication number: 20200101031
    Abstract: Disclosed herein are methods and compositions for treating, ameliorating, and/or preventing Alzheimer's disease in ApoE4-postitive patients using particular compounds and compositions thereof.
    Type: Application
    Filed: September 13, 2019
    Publication date: April 2, 2020
    Inventors: Martin TOLAR, John A. HEY, Petr KOCIS, Jeremy YU
  • Patent number: 10590070
    Abstract: Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: March 17, 2020
    Assignee: Alzheon, Inc.
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Publication number: 20190374514
    Abstract: Methods of treating a disease characterized by amyloid aggregates are provided herein.
    Type: Application
    Filed: February 23, 2018
    Publication date: December 12, 2019
    Applicant: Alzheon, Inc.
    Inventors: Petr Kocis, Martin Tolar, John Hey
  • Patent number: 10471029
    Abstract: Disclosed herein are methods and compositions for treating, ameliorating, and/or preventing Alzheimer's disease in ApoE4-postitive patients using particular compounds and compositions thereof.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: November 12, 2019
    Assignee: Alzheon, Inc.
    Inventors: Martin Tolar, John A. Hey, Petr Kocis, Jeremy Yu
  • Publication number: 20180250249
    Abstract: Disclosed herein are methods for treating, ameliorating, and/or preventing Alzheimer's Disease in a specific patient population using tramiprosate, valyl-3-amino-1-propanesulfonic acid, or a pharmaceutically acceptable salt thereof based upon a combination of APOE4 status and disease severity.
    Type: Application
    Filed: September 9, 2014
    Publication date: September 6, 2018
    Inventors: Susan Abushakra, Aidan Power, Martin Tolar, John Hey, Jeremy Yu, Petr Kocis
  • Publication number: 20180230091
    Abstract: Compounds, pharmaceutical compositions, methods and kits are described for treating or preventing neurodegenerative diseases such as Alzheimer's disease.
    Type: Application
    Filed: August 10, 2016
    Publication date: August 16, 2018
    Inventors: Petr KOCIS, Martin TOLAR, John HEY
  • Publication number: 20170172952
    Abstract: Disclosed herein are methods and compositions for treating, ameliorating, and/or preventing Alzheimer's disease in ApoE4-postitive patients using particular compounds and compositions thereof.
    Type: Application
    Filed: March 23, 2015
    Publication date: June 22, 2017
    Inventors: Martin TOLAR, John A. HEY, Petr KOCIS, Jeremy YU
  • Publication number: 20160376132
    Abstract: A crane including an inner boom, an outer boom, a plurality of guide assemblies arranged along the length of the inner and outer boom and adapted for guiding a plurality of lines, and a multi-line material handling system including a first line having an outgoing portion extending to a sheave block, and an incoming portion returning from the sheave block to a supported anchor device, and a second line having an outgoing portion extending to the sheave block, and an incoming portion returning from the sheave block to the supported anchor device.
    Type: Application
    Filed: September 12, 2016
    Publication date: December 29, 2016
    Inventor: John Hey
  • Patent number: 9463963
    Abstract: A crane including an inner boom, an outer boom, a plurality of guide assemblies arranged along the length of the inner and outer boom and adapted for guiding a plurality of lines, and a multi-line material handling system including a first line having an outgoing portion extending to a sheave block, and an incoming portion returning from the sheave block to a supported anchor device, and a second line having an outgoing portion extending to the sheave block, and an incoming portion returning from the sheave block to the supported anchor device.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: October 11, 2016
    Assignee: National Oilwell Varco, L.P.
    Inventor: John Hey
  • Publication number: 20140155334
    Abstract: The present invention provides, among other things, phosphorylated and pyrophosphate derivatives of mono-, di- and oligosaccharides, as well as structural derivatives of these compounds. These compounds have a variety of uses including for pharmaceutical applications. Also provided are methods of use in the treatment of disease, including diseases related to oxygen delivery.
    Type: Application
    Filed: November 25, 2013
    Publication date: June 5, 2014
    Applicants: Université de Strasbourg, NormOxys, Inc.
    Inventors: Jean-Marie Lehn, Yves Claude Nicolau, Rajamalleswaramma Jogireddy, Adam H. Brockman, John Hey, Yongxin Yu
  • Publication number: 20140142052
    Abstract: The present invention provides phosphorylated and pyrophosphate derivatives of polyols, and structural derivatives of these compounds, and provides pharmaceutical compositions comprising the same. The compounds and compositions disclosed herein have various biological activities, including for example, as allosteric effectors of hemoglobin and/or as kinase inhibitors. The present invention further provides methods for therapy in human or mammalian patients, and methods for synthesis of biologically active compounds and their intermediates.
    Type: Application
    Filed: May 17, 2013
    Publication date: May 22, 2014
    Applicant: NormOxys, Inc.
    Inventors: Jean-Marie Lehn, Yves Claude Nicolau, Srinivasu Pothukanuri, Adam Brockman, John Hey, Jeremy Yu
  • Publication number: 20140088036
    Abstract: The present invention provides, among other things, phosphorylated and pyrophosphate derivatives of mono-, di- and oligosaccharides, as well as structural derivatives of these compounds. These compounds have a variety of uses including for pharmaceutical applications. Also provided are methods of use in the treatment of disease, including diseases related to oxygen delivery.
    Type: Application
    Filed: September 30, 2011
    Publication date: March 27, 2014
    Applicants: UNIVERSITE DE STRASBOURG, NORMOXYS, INC.
    Inventors: Jean Marie Lehn, Yves Claude Nicolau, Rajamalleswaramma Jogireddy, Adam H. Brockman, John Hey, Yongxin Yu