Abstract: Disclosed herein are recombinant meganucleases engineered to bind and cleave a recognition sequence in the mitochondrial DNA (mtDNA) of a eukaryotic cell, such as a plant cell. The disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells, and to a population of genetically-modified eukaryotic cells wherein the mtDNA has been having modified or edited.

Abstract: Disclosed herein are recombinant meganucleases engineered to recognize and cleave a recognition sequence present in the human mitochondrial DNA (mtDNA). The disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells, and to a population of genetically-modified eukaryotic cells wherein the mtDNA has been having modified or edited.

Abstract: A system for natural gas cooling using nitrogen. The system can include a nitrogen liquefier and a natural gas cooler. The nitrogen liquefier can provide liquid nitrogen to the natural gas cooler. One or more heat exchangers of the natural gas cooler can include a gaseous nitrogen output that is in fluid communication with the nitrogen liquefier. In response to receiving gaseous nitrogen at the nitrogen liquefier, from the one or more heat exchangers, a production rate of the the nitrogen liquefier is adjusted.

Abstract: A system for natural gas cooling using nitrogen. The system can include a nitrogen liquefier and a natural gas cooler. The nitrogen liquefier can provide liquid nitrogen to the natural gas cooler. One or more heat exchangers of the natural gas cooler can include a gaseous nitrogen output that is in fluid communication with the nitrogen liquefier. In response to receiving gaseous nitrogen at the nitrogen liquefier, from the one or more heat exchangers, a production rate of the the nitrogen liquefier is adjusted.

Abstract: A detection system for a vehicle, including at least one detection device operable for detecting objects in a detection area. The detection device also includes a first emission antenna, a first reception antenna, and a plurality of extension portions. One of the plurality of extension portions is integrally formed as part of the first emission antenna, and another of the plurality of extension portions is integrally formed as part of the first reception antenna. The first emission antenna generates an emission wave at a predetermined angle which contacts objects in the first detection area and deflects of the objects in the first detection area, and returns to the first reception antenna as a return wave. In an embodiment, the first emission antenna includes at least one Vivaldi wing, and the first reception antenna includes at least one Vivaldi wing.

Abstract: A detection system for a vehicle, including at least one detection device operable for detecting objects in a detection area. The detection device also includes a first emission antenna, a first reception antenna, and a plurality of extension portions. One of the plurality of extension portions is integrally formed as part of the first emission antenna, and another of the plurality of extension portions is integrally formed as part of the first reception antenna. The first emission antenna generates an emission wave at a predetermined angle which contacts objects in the first detection area and deflects of the objects in the first detection area, and returns to the first reception antenna as a return wave. In an embodiment, the first emission antenna includes at least one Vivaldi wing, and the first reception antenna includes at least one Vivaldi wing.

Abstract: Disclosed is a system for detecting approach and/or contact of a user and Ultra High Frequency communication with a portable user apparatus, intended to be embedded on board an automotive vehicle, the system including: a device for detecting approach and/or contact, including a sensor for detecting approach and/or contact and an electronic control unit; a conducting metal surface, suitable for the conduction of electric charges; and a communication device, including an Ultra High Frequency antenna emitting an electromagnetic field at an Ultra High Frequency wavelength, and a management unit for managing the emission and reception of data of the antenna. The conducting metal surface takes the form of a continuous path including a plurality of meanders spread over a length at least equal to: L=?/6 wherein L is a total length of the meanders, and ? is a wavelength of the Ultra High Frequency antenna.

Abstract: A system for natural gas cooling using nitrogen. The system can include a nitrogen liquefier and a natural gas cooler. The nitrogen liquefier can provide liquid nitrogen to the natural gas cooler. One or more heat exchangers of the natural gas cooler can include a gaseous nitrogen output that is in fluid communication with the nitrogen liquefier. In response to receiving gaseous nitrogen at the nitrogen liquefier, from the one or more heat exchangers, a production rate of the the nitrogen liquefier is adjusted.

Abstract: Disclosed is a system for detecting approach and/or contact of a user and Ultra High Frequency communication with a portable user apparatus, intended to be embedded on board an automotive vehicle, the system including: a device for detecting approach and/or contact, including a sensor for detecting approach and/or contact and an electronic control unit; a conducting metal surface, suitable for the conduction of electric charges; and a communication device, including an Ultra High Frequency antenna emitting an electromagnetic field at an Ultra High Frequency wavelength, and a management unit for managing the emission and reception of data of the antenna. The conducting metal surface takes the form of a continuous path including a plurality of meanders spread over a length at least equal to: L=?/6 wherein L is a total length of the meanders, and ? is a wavelength of the Ultra High Frequency antenna.

Abstract: The disclosure generally relates to compositions and uses thereof to treat vision disorders that affect the normal function of the lens in the eye in a subject having or at risk of developing such vision disorders.

Abstract: A computer-implemented method includes scanning, by one or more processors, data that is maintained on one or more social networks, analyzing the scanned data using one or more machine learning techniques, generating custom content associated with a target social entity, initiating interaction with the target social entity, where initiating interaction with the target social entity includes, posting, by the one or more processors, a form of the generated custom content associated with the target social entity to one or more of the target social entity's social networks.

Abstract: A three-magnet assembly configured for use in a position sensing system is disclosed. In an example, the three-magnet assembly establishes a non-linear spatially varying magnetic field configured to be measured by a magnetic field measurement device so that resolvable measurements are spatially distributed in a non-linear fashion. The resolvable measurements are distributed to a relatively higher concentration in at least one first region along a measurement stroke and to a relatively lower concentration in at least one second region along a measurement stroke, the second region being different from the first region. In an example, the different concentrations of resolvable measurements are utilized to spatially vary the precision of a position sensor along a measurement stroke. A system and methods for correlating magnetic field measurements to expected positions are also disclosed.

Abstract: A portable tilted table for cell phones, tablets, pads, electronic books or similar electronic devices is shown. The portable tilted table rests on a flat surface with the electronic device resting on the tilted surface with a footrest preventing the electric device from sliding off the tilted surface. This allows the user to use one hand for the electronic device, having the other hand free for other tasks. A notch in the footrest allows the electronic device to be charged while resting on the tilted surface.

Abstract: Systems and methods for testing ignition properties of particles in a gas. Systems include a test chamber sized to hold a particle to be tested, a gas supply configured to deliver a gas to the test chamber, a heating device configured to heat the particle, and data acquisition equipment configured to collect data associated with the particle and/or the gas. Methods include generating a flow of gas around a particle that is fixed in space relative to the flow of gas in a test chamber, heating the particle and/or heating the gas, and collecting data associated with the particle and/or the gas.

Abstract: An inductive position sensor determines a position of an object. The sensor incudes a circuit board, a wire source coil constructed and arranged to provide a certain operating frequency, a first wire sensing coil, and a second wire sensing coil. The source coil, and first and second sensing coils are embedded in the circuit board, and each of the first and second sensing coils are constructed and arranged to provide an output as the object passes by source coil and the first and second sensing coils. Eddy current generating material is associated with any of the coils so as to provide an eddy current that interferes with wire to wire communication between the sensing coils and the source coil, so as to alter the output of the sensing coils to improve accuracy of the sensor to shape the output.

Abstract: Systems and methods for testing ignition properties of particles in a gas. Systems include a test chamber sized to hold a particle to be tested, a gas supply configured to deliver a gas to the test chamber, a heating device configured to heat the particle, and data acquisition equipment configured to collect data associated with the particle and/or the gas. Methods include generating a flow of gas around a particle that is fixed in space relative to the flow of gas in a test chamber, heating the particle and/or heating the gas, and collecting data associated with the particle and/or the gas.

Abstract: An inductive position sensor determines a position of an object. The sensor incudes a circuit board, a wire source coil constructed and arranged to provide a certain operating frequency, a first wire sensing coil, and a second wire sensing coil. The source coil, and first and second sensing coils are embedded in the circuit board, and each of the first and second sensing coils are constructed and arranged to provide an output as the object passes by source coil and the first and second sensing coils. Eddy current generating material is associated with any of the coils so as to provide an eddy current that interferes with wire to wire communication between the sensing coils and the source coil, so as to alter the output of the sensing coils to improve accuracy of the sensor to shape the output.

Abstract: A laser shock peening system including a workpiece is provided. The laser shock peening system includes a workholding fixture configured to hold the workpiece. The laser shock peening system also includes a laser source configured to emit multiple laser beam pulses on the workpiece. The laser shock peening system further includes an absorptive layer disposed on the workpiece, the absorptive layer configured to absorb the laser beam pulses from the laser source into the workpiece. The laser shock peening system also includes a transparent constraining layer disposed between the laser source and the absorptive layer. The transparent constraining layer is also configured to provide a pressure medium configured to direct multiple reflected laser generated shock waves from the workpiece back into the workpiece. The laser shock peening system also includes a transducer disposed on the workholding fixture and configured to detect multiple acoustic signals emitted from the workpiece.

Abstract: Described herein are methods for the noninvasive immunization of a subject that involve alkyl glycosides. Also described herein are compositions, kits, and devices for the noninvasive immunization of a subject.

Abstract: A laser shock peening system including a workpiece is provided. The laser shock peening system includes a workholding fixture configured to hold the workpiece. The laser shock peening system also includes a laser source configured to emit multiple laser beam pulses on the workpiece. The laser shock peening system further includes an absorptive layer disposed on the workpiece, the absorptive layer configured to absorb the laser beam pulses from the laser source into the workpiece. The laser shock peening system also includes a transparent constraining layer disposed between the laser source and the absorptive layer. The transparent constraining layer is also configured to provide a pressure medium configured to direct multiple reflected laser generated shock waves from the workpiece back into the workpiece. The laser shock peening system also includes a transducer disposed on the workholding fixture and configured to detect multiple acoustic signals emitted from the workpiece.