Abstract: Compositions and methods for treating macular degeneration and other forms of retinal disease whose etiology involves the accumulation of A2E and/or lipofuscin, and, more specifically, for preventing the formation and/or accumulation of A2E are disclosed

Abstract: A system for diagnosing a session initiation protocol (SIP) trunk configuration may include one or more processors coupled to memory. The one or more processors may be collectively operable to execute a diagnostics environment. The diagnostics environment may include an interface module operable to access data associated with a configuration including a set of configuration settings assignable to a SIP trunk. The set of configurations settings may be associated with respective layers and/or sublayers of a network connectivity model. A comparison module may be operable to determine a configuration status of one or more of the layers and/or sublayers associated with the SIP trunk. A display module may be operable to cause the configuration status to be displayed in a user interface. A method of diagnosing a SIP trunk configuration is also disclosed.

Abstract: A system includes a gas turbine system having a compressor, a combustor, and a turbine. The system further includes a power management system configured to supply an injection fluid into a host fluid of the gas turbine system to manage power production of the gas turbine system, wherein the injection fluid comprises a gas mixture comprising oxygen. The system further includes a model-based controller configured to control operation of the gas turbine system, wherein the model-based controller has one or more models including consideration of the injection fluid supplied by the power management system into the host fluid.

Abstract: Certain aspects of the present disclosure provide techniques for to managing electric vehicle fleets and management of charging infrastructure to support the electrical vehicle fleets. An example method for electric vehicle fleet management includes determining that an electric vehicle is in route to a charging site including a plurality of charging stations. The method also includes assigning a charging task to the electric vehicle and assigning the electric vehicle to one of the plurality of charging stations based on one or more vehicle characteristics, one or more operation targets of the charging task, and one or more characteristics of the plurality of charging stations. The method includes, in response to determining that the electric vehicle has plugged into the assigned charging station, associating the electric vehicle with a charging session and allocating charging power to the assigned charging station.

Abstract: The present invention is directed to topical ophthalmic compositions of a lipophilic compound and an oligomeric or polymeric carrier wherein the compositions are useful in the treatment and prevention of macular degeneration. The invention also includes methods of treating macular degeneration by using a topical ophthalmic composition of a lipophilic compound and an oligomeric or polymeric carrier.

Abstract: An electronic device comprises an image sensor, one or more processors, and memory storing instructions for receiving an event recording profile based on configuration data of the electronic device, the configuration data including a location type or a power type; receiving a plurality of images of a scene captured by the image sensor; detecting a trigger event based on one or more of the plurality of images of the scene; in response to detecting the trigger event, identifying an object of interest in one or more of the plurality of images of the scene; creating an event clip from the stored images that include the object of interest, wherein creating the event clip includes configuring a clip length based on the event recording profile; and providing the event clip for display.

Abstract: A hierarchical modular arbitration architecture for a mobile platform guidance system is disclosed. In embodiments, the architecture comprises a hierarchy of arbitration layers, each arbitration layer narrower in scope than the layer above (e.g., mission objective arbitrators, route arbitrators, path arbitrators). Each arbitration layer includes one or more objective-based arbitrators in communication with one or more applications or modes. Each arbitrator receives control input (e.g., from the pilot, from aircraft sensors) and control signals from the level above, selecting a mode to make active based on decision agents within the arbitrator layer which control mode priorities and sequencing (e.g., some flight objectives may involve multiple arbitrators and their subject applications coordinating in sequence).

Abstract: Certain aspects of the present disclosure provide techniques for electric vehicle charging management. In some examples, a method includes detecting a charge session associated with a charging station; generating an encoded identification message that includes an identifier and sending the encoded identification message to the charging station, the encoded identification message configured to cause the vehicle connected to the charging station to alter a battery charging rate based on the identifier; receiving telematics data from the vehicle, the telematics data including the battery charging rate; decoding the identifier from the battery charging rate; and assigning the charge session to an account associated with the vehicle based on the decoded identifier.

Abstract: A wearable device for an attraction system includes a display, a projector oriented at a first oblique angle with respect to the display and configured to project an image onto the display, and a microphone oriented at a second oblique angle with respect to the display. The microphone is configured to receive audio waves deflecting off the display.

Abstract: The present invention relates to novel protein pores and their uses in analyte detection and characterisation. The invention particularly relates to an isolated pore complex formed by a CsgG-like pore and a modified CsgF peptide, or a homologue or mutant thereof, thereby incorporating an additional channel constriction or reader head in the nanopore. The invention further relates to a transmembrane pore complex and methods for production of the pore complex and for use in molecular sensing and nucleic acid sequencing applications.

Abstract: A resin including up to 99.99 weight percent (wt. %) of a first polyolefin grafted with a functional group selected from an ethylenically unsaturated carboxylic acid, a carboxylic acid anhydride, an ester functional group or a combination thereof; and 0.01 to 3.0 wt. % of a tin oxide-based catalyst, where the resin includes 0.2 wt. % to 1.5 wt. % of the functional group from the first polyolefin, the wt. % based on a total weight of the resin. The first polyolefin can be selected from a polyethylene, a polypropylene, an ethylene/alpha-olefin copolymer, a propylene/alpha-olefin copolymer and combinations thereof. The tin oxide-based catalyst can be selected from dibutyltin oxide, dioctyltin oxide and combinations thereof. The resin can be used in a multilayer structure, where a Layer A comprises the resin and a Layer B comprises a polyester, where a first major surface of Layer A is in adhering contact with the second major surface of Layer B.

Abstract: The disclosure describes techniques for interacting with visitors at a visitor interaction system. A method includes obtaining video data captured by the visitor interaction system, identifying an approach of a person, and analyzing the video data to determine an identity of the person. The method includes automatically and without user intervention determining that the person belongs to a visitor groups of a plurality of visitor groups. Each of the visitor groups corresponds to a response model that includes a plurality of response actions. At least one of the response actions includes an autonomous response action. The method includes identifying a response model corresponding to the visitor groups and initiating an autonomous response action associated with the response model. Initiating the autonomous response action including presenting a message to the person, monitoring a response to the message, and sending a report message to the user via a client device.

Abstract: Provided herein are devices, systems, and methods for assessing, treating, and for developing new treatments for pulmonary arterial hypertension (PAH) using pulmonary artery pressure (PAP) values and/or cardiac output (CO) estimates.

Abstract: A low-emission nozzle and receptacle coupling for cryogenic fluid is disclosed. An example nozzle includes a body including a front end and a back end and defining a chamber through which the cryogenic fluid is to flow to the receptacle. The nozzle includes a shaft having a first end and a second end. The shaft is housed within and slidably extending through the chamber. The nozzle includes a poppet coupled to the first end of the shaft and an actuator including a stem coupled to the second end of the shaft. The stem is configured to linearly actuate to cause the shaft and the poppet to linearly actuate. The nozzle includes a coupling assembly coupling the actuator to the back end of the body. The coupling assembly includes insulating material to thermally isolate the actuator from the chamber through which the cryogenic fluid is to flow.

Abstract: An electronic device comprises an image sensor, one or more processors, and memory storing instructions for receiving an event recording profile based on configuration data of the electronic device, the configuration data including a location type or a power type; receiving a plurality of images of a scene captured by the image sensor; detecting a trigger event based on one or more of the plurality of images of the scene; in response to detecting the trigger event, identifying an object of interest in one or more of the plurality of images of the scene; creating an event clip from the stored images that include the object of interest, wherein creating the event clip includes configuring a clip length based on the event recording profile; and providing the event clip for display.

Abstract: In aspects, a visitor interaction system is described for interacting with visitors. The visitor interaction system can obtain video data, identify an approach of a person, and determine an identity of the person. Further, the visitor interaction system can determine that the person belongs to a respective visitor group of a plurality of visitor groups. Each of the plurality of visitor groups corresponds to a response model that includes a plurality of response actions. At least one of the response actions includes an autonomous response action. The visitor interaction system can also identify a response model corresponding to the respective visitor group and initiate an autonomous response action associated with the response model. The visitor interaction system can then send a report message to the user via a client device.

Abstract: A display assistant device comprises a display, a camera, a speaker, microphones, a processor and memory. The memory stores programs comprising instructions that, when executed by the processor, enable a plurality of modes of the display assistant device. The modes include a monitoring mode and an assistant mode. In the monitoring mode, the device is configured to perform a remote monitoring function in which first video captured by the camera is streamed to a remote server system for monitoring uses. The monitoring uses include transmission of the first video to remote client devices authorized to access the first video. In the assistant mode, the device is configured to perform a second plurality of functions that excludes the monitoring function and includes a video communication function in which second video captured by the camera is transmitted to second devices participating in a video communication with a first user of the device.

Abstract: A display assistant device comprises a display, a camera, a speaker, microphones, a processor and memory. The memory stores programs comprising instructions that, when executed by the processor, enable a plurality of modes of the display assistant device. The modes include a monitoring mode and an assistant mode. In the monitoring mode, the device is configured to perform a remote monitoring function in which first video captured by the camera is streamed to a remote server system for monitoring uses. The monitoring uses include transmission of the first video to remote client devices authorized to access the first video. In the assistant mode, the device is configured to perform a second plurality of functions that excludes the monitoring function and includes a video communication function in which second video captured by the camera is transmitted to second devices participating in a video communication with a first user of the device.

Abstract: Automated assembly of a pallet includes advancement of a subject board from a source location to a queue position. The subject board is moved from the queue position to a fastening position by a positioner. Advancement of the subject board occurs while the positioner is in motion between the queue position and the fastening position.

Abstract: An electronic device comprises an image sensor, one or more processors, and memory storing instructions for receiving an event recording profile based on configuration data of the electronic device, the configuration data including a location type or a power type; receiving a plurality of images of a scene captured by the image sensor; detecting a trigger event based on one or more of the plurality of images of the scene; in response to detecting the trigger event, identifying an object of interest in one or more of the plurality of images of the scene; creating an event clip from the stored images that include the object of interest, wherein creating the event clip includes configuring a clip length based on the event recording profile; and providing the event clip for display.