Patents by Inventor John A. Kellum, Jr.

John A. Kellum, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11693014
    Abstract: This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, long-term dialysis. For example, prediction of long-term dialysis treatment can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of approximately fourteen Days measuring hyaluronic acid, death receptor 5, and/or transforming growth factor ?1 can be used to establish the risk of recovery versus non-recovery in patient's having suffered an acute kidney injury.
    Type: Grant
    Filed: January 15, 2020
    Date of Patent: July 4, 2023
    Assignee: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Kai Singbartl, John A. Kellum, Jr.
  • Patent number: 11243202
    Abstract: It is an object of the present invention to provide methods for assessing the efficacy of a remote ischemic preconditioning procedure though the measurement of urinary TIMP-2 and IGFBP7 concentrations.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: February 8, 2022
    Assignees: ASTUTE MEDICAL, INC., UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, WESTFÄLISCHE WILHELMS-UNIVERSITÄT MÜNSTER
    Inventors: Paul McPherson, John A. Kellum, Jr., Alexander Zarbock
  • Publication number: 20200150132
    Abstract: This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, long-term dialysis. For example, prediction of long-term dialysis treatment can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of approximately fourteen Days measuring hyaluronic acid, death receptor 5, and/or transforming growth factor ?1 can be used to establish the risk of recovery versus non-recovery in patient's having suffered an acute kidney injury.
    Type: Application
    Filed: January 15, 2020
    Publication date: May 14, 2020
    Inventors: Kai Singbartl, John A. Kellum, JR.
  • Patent number: 10557856
    Abstract: This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, long-term dialysis. For example, prediction of long-term dialysis treatment can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of approximately fourteen Days measuring hyaluronic acid, death receptor 5, and/or transforming growth factor ?1 can be used to establish the risk of recovery versus non-recovery in patient's having suffered an acute kidney injury.
    Type: Grant
    Filed: September 16, 2011
    Date of Patent: February 11, 2020
    Assignee: University Of Pittsburgh-Of The Commonwealth System Of Higher Education
    Inventors: Kai Singbartl, John A. Kellum, Jr.
  • Publication number: 20180074054
    Abstract: It is an object of the present invention to provide methods for assessing the efficacy of a remote ischemic preconditioning procedure though the measurement of urinary TIMP-2 and IGFBP7 concentrations.
    Type: Application
    Filed: April 8, 2016
    Publication date: March 15, 2018
    Applicants: ASTUTE MEDICAL, INC., UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYS TEM OF HIGHER EDUCATION, WESTFÄLISCHE WILHELMS-UNIVERSITÄT MÜNSTER
    Inventors: Paul McPherson, John A. Kellum, Jr., Alexander Zarbock
  • Patent number: 9551720
    Abstract: This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, renal recovery. For example, renal recovery can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of approximately fourteen Days measuring urinary proteins can be used to establish the risk of recovery versus non-recovery in patient's having suffered an acute kidney injury. Alternatively, the invention describes signature protein expression profiles to establish the probability of renal recovery and/or renal non-recovery.
    Type: Grant
    Filed: January 20, 2012
    Date of Patent: January 24, 2017
    Assignee: University of Pittsburgh—Of the Commonwaelth System of Higher Education
    Inventors: Kai Singbartl, John A. Kellum, Jr.
  • Publication number: 20150241415
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in sepsis patients. In particular, the invention relates to using assays that detect hyaluronic acid as diagnostic and prognostic biomarker assays of renal injury in the sepsis patient.
    Type: Application
    Filed: August 9, 2013
    Publication date: August 27, 2015
    Inventors: Joseph Anderberg, Jeff Gray, Paul McPherson, Kevin Nakamura, James Patrick Kampf, Kai Singbartl, John A. Kellum, JR.
  • Patent number: 8827943
    Abstract: In one aspect, the invention provides a device comprising a catheter. In another aspect, the invention provides a method of removing an agent from blood.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: September 9, 2014
    Assignee: University of Pittsburg—Of The Commonwealth System of Higher Education
    Inventors: George Oliviu Angheloiu, John A. Kellum, Jr., William D. Anderson, Catalin Toma
  • Publication number: 20130323751
    Abstract: This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, renal recovery. For example, renal recovery can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of approximately fourteen Days measuring urinary proteins can be used to establish the risk of recovery versus non-recovery in patient's having suffered an acute kidney injury. Alternatively, the invention describes signature protein expression profiles to establish the probability of renal to recovery and/or renal non-recovery.
    Type: Application
    Filed: January 20, 2012
    Publication date: December 5, 2013
    Applicant: University of Pittsburgh - of the Common-Wealth System of Higher Education
    Inventors: Kai Singbartl, John A. Kellum, JR.
  • Patent number: 8501489
    Abstract: This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, long-term dialysis. For example, prediction of long-term dialysis treatment can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of hyaluronic acid can be used to determine whether a patient having suffered acute kidney injury will require long-term dialysis.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: August 6, 2013
    Assignee: University of Pittsburgh—Of The Commonwealth System of Higher Education
    Inventors: Kai Singbartl, John A. Kellum, Jr.
  • Patent number: 8398576
    Abstract: The invention provides a system and a method for removal of contrast from blood. In one aspect, the invention provides a catheter for removal of contrast from the veins that drain the cerebral circulation. In a second aspect, the invention provides a method for removing contrast from blood by contacting the blood with a sorbent.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: March 19, 2013
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: George Oliviu Angheloiu, John A. Kellum, Jr., William D. Anderson, Catalin Toma
  • Publication number: 20120077690
    Abstract: This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, long-term dialysis. For example, prediction of long-term dialysis treatment can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of approximately fourteen Days measuring hyaluronic acid, death receptor 5, and/or transforming growth factor ?1 can be used to establish the risk of recovery versus non-recovery in patient's having suffered an acute kidney injury.
    Type: Application
    Filed: September 16, 2011
    Publication date: March 29, 2012
    Inventors: Kai Singbartl, John A. Kellum, JR.
  • Publication number: 20100081148
    Abstract: This invention is related to the field of the prevention and treatment of kidney disease. The treatment of kidney disease may be tailored depending upon the need for, or expectation of, long-term dialysis. For example, prediction of long-term dialysis treatment can be determined by monitoring urine biomarkers related to the development of chronic kidney disease. For example, a normalized time course of hyaluronic acid can be used to determine whether a patient having suffered acute kidney injury will require long-term dialysis.
    Type: Application
    Filed: September 23, 2009
    Publication date: April 1, 2010
    Inventors: Kai Singbartl, John A. Kellum, JR.
  • Publication number: 20080281248
    Abstract: The invention provides a system and a method for removal of contrast from blood. In one aspect, the invention provides a catheter for removal of contrast from the veins that drain the cerebral circulation. In a second aspect, the invention provides a method for removing contrast from blood by contacting the blood with a sorbent.
    Type: Application
    Filed: April 2, 2008
    Publication date: November 13, 2008
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: George Oliviu Angheloiu, John A. Kellum, JR., William D. Anderson, Catalin Toma