Abstract: Disclosed are methods and compositions for treating, inhibiting, and/or preventing heterotopic ossification in a subject in need thereof. Particularly disclosed are methods for treating, inhibiting, and/or preventing heterotopic ossification in a subject in need thereof by administering to the subject a therapeutic agent such as an immune checkpoint inhibitor and/or Fetuin-A or a variant thereof. Also disclosed are pharmaceutical compositions and pharmaceutical kits comprising an immune checkpoint inhibitor and/or Fetuin-A or a variant thereof for treating, inhibiting, and/or preventing heterotopic ossification in a subject in need thereof.

Abstract: Provided herein are immunomodulatory nanoparticles, compositions containing the same, and methods of use thereof, such as for the treatment of traumatic brain injury.

Abstract: Disclosed herein are methods for obtaining endometrial stromal fibroblast cells from pluripotent stem cells, such as induced pluripotent stem cells. The present disclosure also provides methods of obtaining a three-dimensional, multilayered endometrial tissue composition. Methods of using the cells and tissue compositions in drug screening and therapeutic applications are also provided.

Abstract: Provided herein are immunomodulatory nanoparticles, compositions containing the same, and methods of use thereof, such as for the treatment of traumatic brain injury.

Abstract: Disclosed are methods and compositions for treating, inhibiting, and/or preventing heterotopic ossification in a subject in need thereof. Particularly disclosed are methods for treating, inhibiting, and/or preventing heterotopic ossification in a subject in need thereof by administering to the subject a therapeutic agent such as an immune checkpoint inhibitor and/or Fetuin-A or a variant thereof. Also disclosed are pharmaceutical compositions and pharmaceutical kits comprising an immune checkpoint inhibitor and/or Fetuin-A or a variant thereof for treating, inhibiting, and/or preventing heterotopic ossification in a subject in need thereof.

Abstract: A certification management system helps an organization develop and maintain a repository of current certification status of employees. The system may integrate multiple learning management systems and other enterprise level systems across the organization. The system facilitates identifying and enrolling targeted employees for any number and type of certification programs. The system may also implement and support reconfiguring certification programs, for example, during training, and enforcing recertification requirements according to maturing business needs. The system provides automated workflows that facilitate a formal, structured approach to the development and recognition of specific specialized skills at scale by infusing more consistency, rigor, and objectivity.

Abstract: A certification management system helps an organization develop and maintain a repository of current certification status of employees. The system may integrate multiple learning management systems and other enterprise level systems across the organization. The system facilitates identifying and enrolling targeted employees for any number and type of certification programs. The system may also implement and support reconfiguring certification programs, for example, during training, and enforcing recertification requirements according to maturing business needs. The system provides automated workflows that facilitate a formal, structured approach to the development and recognition of specific specialized skills at scale by infusing more consistency, rigor, and objectivity.

Abstract: A pivot bar for a tiltable window sash may include an elongated body, an anti-rotation feature and a retaining finger. The elongated body has first and second opposing ends and first and second opposing surfaces extending between the first and second ends. The elongated body also has a first longitudinal axis extending through the first and second ends. The first end may be configured to be received in a window balance assembly. The retaining finger may extend from the second surface and may be configured to engage the tiltable window sash.

Abstract: A vehicle safety system and method for controlling usage of mobile devices in a vehicle is disclosed that includes determining mobile device location in the vehicle; determining vehicle movement; determining whether device is being used by the driver based on device location; and monitoring or limiting usage of the device based on whether its being used by the driver while the vehicle is moving. An electronic beacon located in the vehicle can be used in determining device location. The method can include monitoring activation and usage of device functionality; maintaining an enforcement list of functionality to be limited when used by the driver; determining if any functionality on the enforcement list is attempting to activate, and if so limiting or disabling activation of that functionality. The method can include generating a device motion/usage profile for the driver while driving, and scoring the driver based on the device motion/usage profile.

Abstract: A vehicle safety system and method for controlling usage of mobile devices in a vehicle is disclosed that includes determining mobile device location in the vehicle; determining vehicle movement; determining whether device is being used by the driver based on device location; and monitoring or limiting usage of the device based on whether its being used by the driver while the vehicle is moving. An electronic beacon located in the vehicle can be used in determining device location. The method can include monitoring activation and usage of device functionality; maintaining an enforcement list of functionality to be limited when used by the driver; determining if any functionality on the enforcement list is attempting to activate, and if so limiting or disabling activation of that functionality. The method can include generating a device motion/usage profile for the driver while driving, and scoring the driver based on the device motion/usage profile.

Abstract: A vehicle safety system and method for controlling usage of mobile devices in a vehicle is disclosed that includes determining mobile device location in the vehicle; determining vehicle movement; determining whether device is being used by the driver based on device location; and monitoring or limiting usage of the device based on whether its being used by the driver while the vehicle is moving. An electronic beacon located in the vehicle can be used in determining device location. The method can include monitoring activation and usage of device functionality; maintaining an enforcement list of functionality to be limited when used by the driver; determining if any functionality on the enforcement list is attempting to activate, and if so limiting or disabling activation of that functionality. The method can include generating a device motion/usage profile for the driver while driving, and scoring the driver based on the device motion/usage profile.

Abstract: A vehicle safety system and method for controlling usage of mobile devices in a vehicle is disclosed that includes determining mobile device location in the vehicle; determining vehicle movement; determining whether device is being used by the driver based on device location; and monitoring or limiting usage of the device based on whether its being used by the driver while the vehicle is moving. An electronic beacon located in the vehicle can be used in determining device location. The method can include monitoring activation and usage of device functionality; maintaining an enforcement list of functionality to be limited when used by the driver; determining if any functionality on the enforcement list is attempting to activate, and if so limiting or disabling activation of that functionality. The method can include generating a device motion/usage profile for the driver while driving, and scoring the driver based on the device motion/usage profile.

Abstract: A certification management system helps an organization develop and maintain a repository of current certification status of employees. The system may integrate multiple learning management systems and other enterprise level systems across the organization. The system facilitates identifying and enrolling targeted employees for any number and type of certification programs. The system may also implement and support reconfiguring certification programs, for example, during training, and enforcing recertification requirements according to maturing business needs. The system provides automated workflows that facilitate a formal, structured approach to the development and recognition of specific specialized skills at scale by infusing more consistency, rigor, and objectivity.

Abstract: A pivot bar for a tiltable window sash may include an elongated body, an anti-rotation feature and a retaining finger. The elongated body has first and second opposing ends and first and second opposing surfaces extending between the first and second ends. The elongated body also has a first longitudinal axis extending through the first and second ends. The first end may be configured to be received in a window balance assembly. The retaining finger may extend from the second surface and may be configured to engage the tiltable window sash.

Abstract: An air and/or debris dam for moving coil balance assembly for a hung window is disclosed. The air and/or debris dam is located between the carrier and a mounting location of a moving coil window balance assembly. The air and/or debris dam can travel within the jamb channel of a window frame assembly to inhibit airflow and/or the deposition of dust and/or debris in the jamb channel.

Abstract: An in-line production apparatus and a method for composition control of copper indium gallium diselenide (CIGS) solar cells fabricated by a co-evaporation deposition process. The deposition conditions are so that a deposited Cu-excessive overall composition is transformed into to a Cu-deficient overall composition, the final CIGS film. Substrates with a molybdenum layer move through the process chamber with constant speed. The transition from copper rich to copper deficient composition on a substrate is detected by using sensors which detect a physical parameter related to the transition. A preferred embodiment sensors are provided that detect the composition of elements in the deposited layer. A controller connected to the sensors adjusts the fluxes from the evaporant sources in order provide a CIGS layer with uniform composition and thickness over the width of the substrate.

Abstract: An air and/or debris dam for moving coil balance assembly for a hung window is disclosed. The air and/or debris dam is located between the carrier and a mounting location of a moving coil window balance assembly. The air and/or debris dam can travel within the jamb channel of a window frame assembly to inhibit airflow and/or the deposition of dust and/or debris in the jamb channel.

Abstract: An air and/or debris dam for moving coil balance assembly for a hung window is disclosed. The air and/or debris dam is located between the carrier and a mounting location of a moving coil window balance assembly. The air and/or debris dam can travel within the jamb channel of a window frame assembly to inhibit airflow and/or the deposition of dust and/or debris in the jamb channel.

Abstract: Thin-film solar cells of the CIGS-type use two integrally formed buffer layers, a first ALD Zn(O,S) buffer layer on top of the CIGS-layer and a second ALD ZnO-buffer layer on top of the first buffer layer. Both buffer layers are deposited in the same process step using ALD (atom layer deposition). The technology also relates to a method of producing the cell and a process line for manufacturing of the cell structure.