Abstract: The invention relates to compounds of formula wherein R1 is a 5 or 6 membered heteroaryl group, containing 1 to 3 heteroatoms, selected from N, O or S, and which groups are optionally substituted by one or two substituents, which are lower alkyl, —(CH2)nOH, halogen or lower alkoxy, and wherein the heteroaryl groups may be optionally linked to the pyrazole ring via an alkylene or alkenyl group, or is phenyl, optionally substituted by one or two substituents being lower alkyl, hydroxy-lower alkyl, halogen, hydroxy or lower alkoxy or is —O(CH2)n,phenyl, benzofuryl, indolyl or benzothiophenyl, or is —S-lower alkyl; R2 and R4 are independently from each other hydrogen, cyano or —S(O)2-phenyl; R3 is hydrogen, halogen or is a 5 or 6 membered heteroaryl group, containing 1 to 3 heteroatoms, selected from N, O or S, and which groups are optionally substituted by one or two substituents, which are lower alkyl, —(CH2)n-aryl, hydroxy, halogen, lower alkoxy, morpholin

Abstract: The invention relates to cyclic heteroaromatic compounds, containing at least one nitrogen atom, and to their use in the manufacture of medicaments for the treatment of diseases, related to adenosine receptor modulators, such as Alzheimer's disease, Parkinson's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, asthma, allergic responses, hypoxia, ischaemia, seizure, substance abuse, sedation and they may be active as muscle relaxants, antipsychotics, anti epileptics, anticonvulsants and cardiaprotective agents.

Abstract: A preferred embodiment of the present invention provides a cell site base station configuration for a wireless communications system that makes use of a sectorized base station co-located with an omnidirectional base station. The sectorized base station has a sectorized antenna system and the omnidirectional base station has an omnidirectional antenna. The configuration may also include a controller that monitors the base station for communications links subject to adverse conditions and reassigns any such links to the omnidirectional base station. The adverse conditions monitored for may include multiple fade, equipment failure and a lack of available channels. The controller may also monitor the omnidirectional base station for links that can be moved to the sectorized base station and reassign any such links to the sectorized base station. The configuration may also include a network that interconnects the sectorized base station, the omnidirectional base station and the controller.

Abstract: A laboratory-scale device for assisting in the simulation of heat setting conditions includes a pair of laterally spaced-apart flexible heat-resistant cords (e.g., formed of aramid fibers) tensioned between forward and rearward rigid cross-support bars. At least one rigid tensioning bar is provided parallel to the support cords and extending between the cross-support bars so as to maintain the desired tension on the flexible heat-resistant cords. The tensioning bar thus allows for manual or automated lateral winding of the synthetic heat-settable fibers or yarns about the spaced-apart heat-resistant cords during preparation of the device for a laboratory test run. The tensioning bar may thereafter be removed once the device has been secured in position with the laboratory heat-setting oven. In such a manner, therefore, various effects on heat-setting conditions simulating can be investigated.

Abstract: Crosslinkable polymers, suitable for use in the finishing of keratinous fibres such as wool, have polyoxyalkylene chains in which the alkylene groups consist of unbranched chains of not less than 3 carbon atoms. The polymer molecule contains at least two groupings capable of crosslinking, for example thiol, isocyanate, or thiosulphate groups, and the molecule also contains at least two carboxylic acid residues at least one of which is the residue of a polycarboxylic acid. The polyoxyalkylene chains are themselves linked at both ends to the rest of the molecule by carboxylic ester linkages. Particularly preferred compounds are water soluble and contain one or more solubilizing groups such as thiosulphate or the bi-sulphite adduct of isocyanate or, in the case of compounds with thiol groups, salt forming carboxylic groups. The compounds may be applied to textile fibres as aqueous emulsions or solutions and may be cured by drying in hot air or by steam.