Patents by Inventor John A. Main

John A. Main has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210277103
    Abstract: Specific binding members directed to eotaxin-1, in particular human antibodies and antibody fragments against human eotaxin-1 and especially those which neutralise eotaxin-1 activity. The antibodies VH and/or VL domain of the scFv fragment herein termed CAT-212 and of the IgG4 antibody herein termed CAT 213. One or more complementary determining regions (CDRs) of the CAT-212/-213 VH and/or VL domains, especially VH CRD3 in other antibody framework regions. Compositions containing specific binding members, and their use in methods of inhibiting or neutralising eotaxin, including methods of treatment of the human or animal body by therapy.
    Type: Application
    Filed: September 3, 2020
    Publication date: September 9, 2021
    Inventors: Tristan John VAUGHAN, Alison Jane Wilton, Stephen J. Smith, Sarah Helen Main
  • Publication number: 20200049498
    Abstract: A method of calibrating a contact probe having a deflectable stylus and configured to provide at least one signal which is indicative of the extent of deflection of the stylus, the contact probe being mounted on a coordinate positioning machine which facilitates reorientation of the contact probe about at least one axis. The method includes: taking measurement data obtained with the contact probe positioned at a plurality of different orientations about the at least one axis; and determining from the measurement data at least one gain variation model which models any apparent variation in the gain of the at least one probe signal dependent on the orientation of the contact probe about the at least one axis.
    Type: Application
    Filed: November 9, 2017
    Publication date: February 13, 2020
    Applicant: RENISHAW PLC
    Inventors: Martin Simon REES, Toby John MAIN, James Arash SHABANI
  • Publication number: 20100157478
    Abstract: A storage apparatus is provided. A storage apparatus can include a storage device having one or more unique device identifiers disposed in, on, or about the storage apparatus. One or more computer readable and writeable data storage areas can be disposed in, on, or about the storage apparatus. One or more computer readable data storage areas can also be disposed in, on, or about the storage apparatus. One or more computer readable instruction sets can be disposed in, on, or about the storage apparatus. The execution of all or a portion of the one or more computer readable instruction sets can be contingent upon the successful authentication of all or a portion of the one or more device identifiers.
    Type: Application
    Filed: December 18, 2008
    Publication date: June 24, 2010
    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
    Inventors: Craig N. Changstrom, John Main, David H. Hanes
  • Publication number: 20070083815
    Abstract: Methods for processing a video stream are provided. One embodiment comprises generating a comparison signature for a frame of a video stream and comparing the comparison signature to a reference signature. In another embodiment, a method comprises generating a reference signature for a frame of a video stream and assigning an action to the frame containing the reference signature. Example system embodiments for implementing the aforementioned methods are also provided.
    Type: Application
    Filed: October 11, 2005
    Publication date: April 12, 2007
    Inventors: Alexandre Delorme, John Main
  • Publication number: 20060021614
    Abstract: An apparatus and method for the self-administration of a plurality of doses of an intranasal liquid pharmaceutical composition, including opioid analgesics, that includes a drug delivery device containing a plurality of sealed vials, each vial containing a predetermined volume of the pharmaceutical composition, a pump assembly for conveying the liquid pharmaceutical composition from the interior of the vial and discharging it as a nasal spray in response to manual activation by the patient, and programmable means for sequentially advancing a vial to the ready position after passage of a prescribed time interval following the last activation of the delivery device.
    Type: Application
    Filed: August 16, 2005
    Publication date: February 2, 2006
    Inventors: Daniel Wermeling, Ryan Vallance, Aravind Balasubramaniam, Bruce Walcott, John Main, James Lumpp
  • Publication number: 20050050062
    Abstract: An index validation system comprises a processor and a validator accessible by the processor. The validator is adapted to access index data corresponding to video data and validate the index data after editing of the video data.
    Type: Application
    Filed: August 25, 2003
    Publication date: March 3, 2005
    Inventors: David Hanes, John Main
  • Publication number: 20050033876
    Abstract: A method of guaranteeing a minimum sustained data transfer rate to a chosen device connected to a USB bus. A set of filter drivers are inserted in the driver stacks for at least two USB devices. These filter drivers are controlled by a filter driver controller that provides and receives information from the filter drivers. When a particular device needs a minimum sustained bandwidth for a transaction, the filter driver for that device notifies the filter driver controller. The filter driver controller then instructs the filter drivers for at least one other device to start interfering with USB transactions. This interference prevents the interfered with devices from using any of the USB bus bandwidth thereby providing a minimum sustained bandwidth to the non-interfered with device.
    Type: Application
    Filed: September 13, 2004
    Publication date: February 10, 2005
    Inventors: David Hanes, John Main, Stephen Bayless
  • Patent number: 6213984
    Abstract: A cartridge and system are described for automatically metering a predetemined dosage of a medicament. The cartridge includes a tab on its exterior, and a dispensing gun which receives the cartridge has a detent for stopping forward movement of the upper end of a trigger when the detent contacts the tab on the cartridge. When the detent contacts the tab on the cartridge, no further medicament can be dispensed on that stroke of the trigger.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: April 10, 2001
    Inventors: Donovan R. Lane, John Main, Peter Murphy
  • Patent number: 6188160
    Abstract: A smart material control system and related method is disclosed for adaptively controlling the movement of an adaptive structure. The adaptive structure includes a smart material layer bonded to a conductive substrate in a bimorph configuration. A charge projector, such as an electron gun, is utilized to project charges onto the smart material layer of the adaptive structure. A voltage/charge source adaptively controls the potential of the conductive substrate. Depending on the placement of the projected charges and the adaptively controlled potential of the conductive substrate the displacement/curvature is precisely controlled. In an alternate embodiment, two smart material layers are bonded together to form an adaptive structure controlled independently in the x- and y- directions. Also, an array of charge projectors and/or conductive substrate sections may be used to provide varying and broad control of adaptive structures.
    Type: Grant
    Filed: September 11, 1998
    Date of Patent: February 13, 2001
    Assignee: University of Kentucky Research Foundation
    Inventors: John A. Main, George C. Nelson
  • Patent number: 4932975
    Abstract: A dynamic prosthetic vertebral body for use in a cavity left by resection of a natural vertebral body and adjacent intervertebral discs. The prosthesis includes a pair of rigid housings joined by a connecting structure that is operable to shift the housings apart into supportive engagement with the healthy vertebral bodies adjacent the site of the resected body. Anchoring pins project outwardly in axial directions from the respective housings for secure fixation to the healthy vertebral bodies. Within the chamber of each housing is a rigid suspension plate surrounded by an elastomeric suspension medium, and the suspension plates of the two housings are joined by the expandable connecting structure. The relative sizes of the suspension plates and the chambers in which they are received allow limited movement of the housings, resulting in a prosthesis that provides the required support but also mimics the dynamics of a normal vertebra and adjacent discs.
    Type: Grant
    Filed: October 16, 1989
    Date of Patent: June 12, 1990
    Assignee: Vanderbilt University
    Inventors: John A. Main, Mark E. Wells, Tony S. Keller
  • Patent number: 4354711
    Abstract: A vehicle wheel assembly comprises a detachable wheel mounted on a radial wheel mounting flange using a single wheel fastener and a conical disc spring to secure the wheel to the wheel mounting flange.The conical disc spring is deflected to a preselected compressed state by the fastener to exert a predetermined axial clamping force uniformly along an annular region of contact between the wheel and the disc spring and to resiliently pre-load the wheel bearings. A lock prevents the single fastener from working loose.
    Type: Grant
    Filed: April 21, 1980
    Date of Patent: October 19, 1982
    Assignee: Kelsey-Hayes Co.
    Inventor: John A. Main
  • Patent number: 4217003
    Abstract: A trim attachment for a motor vehicle wheel includes a plurality of generally conical retention members which engage and secure the trim attachment directly to complementary conical surfaces on conventional threaded lug nuts utilized to retain the wheel in the vehicle. The retention members are spaced about the trim attachment in a pattern corresponding to that of the wheel lug nut. The members include a central conical surface which engages the conical portion of the lug nut, a stop structure positioned uniformly at one end of each conical surface which engages the body of the lug nut, a resilient camming structure disposed uniformly at the other end of each conical surface which resiliently engages the conical surface of a lug nut and a free standing triangular tab adjacent the camming surface and pointing away therefrom which guides and engages the trim attachment onto the lug nuts.
    Type: Grant
    Filed: October 1, 1979
    Date of Patent: August 12, 1980
    Assignee: Kelsey Hayes Co.
    Inventor: John A. Main
  • Patent number: D256350
    Type: Grant
    Filed: February 21, 1978
    Date of Patent: August 12, 1980
    Assignee: Kelsey Hayes Co
    Inventor: John A. Main
  • Patent number: D258876
    Type: Grant
    Filed: February 13, 1978
    Date of Patent: April 14, 1981
    Assignee: Kelsey-Hayes Co.
    Inventor: John A. Main
  • Patent number: D262616
    Type: Grant
    Filed: January 14, 1980
    Date of Patent: January 12, 1982
    Assignee: Kelsey-Hayes Company
    Inventor: John A. Main
  • Patent number: D264834
    Type: Grant
    Filed: January 14, 1980
    Date of Patent: June 8, 1982
    Assignee: Kelsey-Hayes Co.
    Inventor: John A. Main
  • Patent number: D264836
    Type: Grant
    Filed: February 1, 1980
    Date of Patent: June 8, 1982
    Assignee: Kelsey-Hayes Co.
    Inventors: John A. Main, Lawrence K. Shinoda
  • Patent number: D265984
    Type: Grant
    Filed: January 14, 1980
    Date of Patent: August 31, 1982
    Assignee: Kelsey-Hayes Co.
    Inventor: John A. Main
  • Patent number: D282835
    Type: Grant
    Filed: April 14, 1983
    Date of Patent: March 4, 1986
    Assignee: Kelsey-Hayes Company
    Inventor: John A. Main
  • Patent number: D282836
    Type: Grant
    Filed: April 14, 1983
    Date of Patent: March 4, 1986
    Assignee: Kelsey-Hayes Company
    Inventor: John A. Main