Patents by Inventor John A. Manthey

John A. Manthey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11197879
    Abstract: This invention relates to a flavonoid composition that includes eriocitrin. The flavonoid may be included in a complex with other bioflavonoids. The composition may also include neoeriocitrin. This invention also relates to methods of using the composition, including for reducing IL-6 or MCP-1 treating inflammation, and treating symptoms of metabolic syndrome.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: December 14, 2021
    Assignees: INGREDIENTS BY NATURE, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
    Inventors: Robert M. Brewster, John A. Manthey
  • Publication number: 20200246367
    Abstract: This invention relates to a flavonoid composition that includes eriocitrin. The flavonoid may be included in a complex with other bioflavonoids. The composition may also include neoeriocitrin. This invention also relates to methods of using the composition, including for reducing IL-6 or MCP-1 treating inflammation, and treating symptoms of metabolic syndrome.
    Type: Application
    Filed: February 6, 2020
    Publication date: August 6, 2020
    Applicants: INGREDIENTS BY NATURE, U.S. DEPARTMENT OF AGRICULTURE
    Inventors: Robert M. BREWSTER, John A. MANTHEY
  • Patent number: 10596185
    Abstract: This invention relates to a flavonoid composition that includes eriocitrin. The flavonoid may be included in a complex with other bioflavonoids. The composition may also include neoeriocitrin. This invention also relates to methods of using the composition, including for reducing IL-6 or MCP-1 levels, treating inflammation, and treating symptoms of metabolic syndrome.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: March 24, 2020
    Assignees: INGREDIENTS BY NATURE, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
    Inventors: Robert M. Brewster, John A. Manthey
  • Publication number: 20170014439
    Abstract: This invention relates to a flavonoid composition that includes eriocitrin. The flavonoid may be included in a complex with other bioflavonoids. The composition may also include neoeriocitrin. This invention also relates to methods of using the composition, including for reducing IL-6 or MCP-1 levels, treating inflammation, and treating symptoms of metabolic syndrome.
    Type: Application
    Filed: March 31, 2015
    Publication date: January 19, 2017
    Inventors: Robert M. Brewster, John A. Manthey
  • Patent number: 8343559
    Abstract: A method for removing furanocoumarins from a liquid includes the steps of incubating the liquid with fungal hyphae for at least about two hours and removing the hyphae from the liquid by a filtration step. The furanocoumarins can be recovered from the hyphae using methods within the ordinary skill in the art. The method is useful for the removal of furanocoumarins from furanocoumarin-containing citrus juice so that the juice can be safely consumed by humans taking drugs that are metabolized by P450 CYP3A, which is the enzyme responsible for the metabolism of many widely-prescribed medications.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: January 1, 2013
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: John A. Manthey, Kyung Myung, Jan A. Narciso
  • Publication number: 20110167009
    Abstract: Embodiments of the invention are directed to manufacturing a medical device in a way that minimizes the possibility of defects. Because of the general increasing desire to eliminate lead from the environment, electronic producers are removing lead from their manufacturing processes. The lead had beneficial qualities, however, in that it prevented other metals, in particular tin, from developing “whiskers,” believed to be caused from thermal and mechanical stress of the tin parts or components. Removing the lead has caused an increasing incidence of failure in electronic devices. Many vendors, believing that lead-free devices are universally desirable, routinely substitute lead-free components for components that previously contained lead. Oftentimes these substitutions are made without knowledge of the buyer. Some devices, in particular life-saving devices, may be adversely affected by such a substitution.
    Type: Application
    Filed: January 6, 2010
    Publication date: July 7, 2011
    Applicant: Physio-Control, Inc.
    Inventors: Todd H. Klump, Dock A. Brown, John A. Manthey, Oscar Hernandez Rojas, Reza Sharif, Xiaodong Zou
  • Patent number: 7683095
    Abstract: Compositions and methods for the treatment, reduction and/or prevention of cardiovascular diseases and disorders are described. Individuals at high risk for developing or having cardiovascular disease or disorder may be treated with an effective dose of a polymethoxyflavone including limocitrin derivatives, quercetin derivatives, naturally occurring polymethoxyflavones, tocotrienols, and mixtures of these compounds.
    Type: Grant
    Filed: May 26, 2004
    Date of Patent: March 23, 2010
    Assignees: The United States of America as represented by the Secretary of Agriculture, KGK Synergize, Inc.
    Inventors: Najla Guthrie, Elzbieta Maria Kurowska, John A. Manthey
  • Patent number: 6987125
    Abstract: Compositions and methods for the treatment, reduction and/or prevention of cardiovascular diseases and disorders are described. Individuals at high risk for developing or having cardiovascular disease or disorder may be treated with an effective dose of a polymethoxyflavone including limocitrin derivatives, quercetin derivatives, naturally occurring polymethoxyflavones, tocotrienols, and mixtures of these compounds.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: January 17, 2006
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Najla Guthrie, Elzbieta Maria Kurowska, John A. Manthey, Sylvia Horowitz, Robert M. Horowitz
  • Publication number: 20040214882
    Abstract: Compositions and methods for the treatment, reduction and/or prevention of cardiovascular diseases and disorders are described. Individuals at high risk for developing or having cardiovascular disease or disorder may be treated with an effective dose of a polymethoxyflavone including limocitrin derivatives, quercetin derivatives, naturally occurring polymethoxyflavones, tocotrienols, and mixtures of these compounds.
    Type: Application
    Filed: May 26, 2004
    Publication date: October 28, 2004
    Inventors: Najla Guthrie, Elzbieta Maria Kurowska, John A. Manthey
  • Patent number: 6184246
    Abstract: A method of inhibiting the production of cytokines, particularly inhibiting the production of tumor necrosis factor&agr;, interleukin-10, and macrophage inflammatory protein-1&agr; and the like, in a mammal, including a human, in need thereof which involves administering to such mammal an effective amount, preferably cytokine production inhibiting amount, of a polymethoxylated flavone.
    Type: Grant
    Filed: July 30, 1999
    Date of Patent: February 6, 2001
    Assignees: The United States of America as represented by the Secretary of Agriculture, Amgen, Inc.
    Inventors: John A. Manthey, Carl L. Manthey, Antonio Montanari
  • Patent number: 4164180
    Abstract: An improved hammer bank assembly includes a plurality of spaced-apart hammers, each of the hammers including a substantially planar hammer body containing an electrical coil, with each hammer body being supported for movement in a predetermined plane. A hammer head is attached to and coplanar with each hammer body. Also included are a plurality of flat permanent magnets interleaved with the plurality of hammers so that adjacent ones of the permanent magnets oppose but are separated from each hammer body. A plurality of hammer guide members are provided, one for each hammer, with each hammer guide member defining therein an elongated groove in which is received at least a portion of each hammer head.
    Type: Grant
    Filed: September 29, 1977
    Date of Patent: August 14, 1979
    Assignee: Interface Mechanisms, Inc.
    Inventors: Larry P. Ellefson, Robert J. Brooks, Kenneth G. Real, John A. Manthey
  • Patent number: D809686
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: February 6, 2018
    Assignee: Illumagear, Inc.
    Inventors: Andrew Royal, John A. Manthey, Alexander Michael Diener, Luke Springer, Aaron Johnson, Chad Brinckerhoff, Tyler Hart