Patents by Inventor John A. McCauley

John A. McCauley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Iminopyrimidine NMDA NR2B receptor antagonists
    Publication number: 20020013329
    Abstract: Compounds described by the chemical structural formula 1
    Type: Application
    Filed: June 25, 2001
    Publication date: January 31, 2002
    Inventors: David A. Claremon, John A. McCauley, Nigel J. Liverton, Cory R. Theberge
  • 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
    Patent number: 6316474
    Abstract: Benzimidazoles, substituted in the 2-position by substituted benzyl groups or heteroaryl groups are effective as NMDA NR2B antagonists and are useful for relieving pain.
    Type: Grant
    Filed: October 25, 2000
    Date of Patent: November 13, 2001
    Assignee: Merck & Co., Inc.
    Inventors: John A. McCauley, Cory R. Theberge, Nigel J. Liverton, David A. Claremon, Christopher F. Claiborne
  • 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
    Patent number: 6291499
    Abstract: Novel 4-substituted cyclohexanes substituted in the 1-position with 2-benzimidazoles, 2-imidazopyridines, or 4-imidazoles either directly or through a C1-C4alkyl, cycloalkyl, hydroxyalkyl, alkoxy or aminoalkyl chain are effective as NMDA NR2B antagonists useful for relieving pain.
    Type: Grant
    Filed: October 25, 2000
    Date of Patent: September 18, 2001
    Assignee: Merck & Co., Inc.
    Inventors: Wayne Thompson, David A. Claremon, Peter M. Munson, John A. McCauley
  • Processes and intermediates for preparing macrocycles
    Patent number: 5621108
    Abstract: Novel processes for the preparation of lactam- and lactone-containing macrocyles are provided. In preferred embodiments, rapamycin and demethoxyrapamycin are prepared by a convergent synthesis regime. Intermediates useful in the synthetic processes are also provided.
    Type: Grant
    Filed: December 5, 1994
    Date of Patent: April 15, 1997
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Amos B. Smith, III, Stephen M. Condon, Johnnie L. Leazer, Jr., Robert E. Maleczka, John A. McCauley, James W. Leahy