Patents by Inventor John A. McLaughlin

John A. McLaughlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8914312
    Abstract: Method of selectively predicting hydrocarbon concentration in a sample of unknown hydrocarbon concentration, by (i) separately subjecting two or more samples of known hydrocarbon concentration to infrared (IR) radiation, (ii) separately detecting an IR signal from the samples of known hydrocarbon concentration, (iii) analyzing the IR signals using a multivariate chemometric technique to produce a training data set, (iv) generating a predictive model for hydrocarbon concentration based on the training data set, (v) subjecting the unknown sample to infrared (IR) radiation, (vi) detecting an IR signal from the unknown sample, (vii) applying the predictive model to the IR signal from the unknown sample. Thereafter, as step (viii), hydrocarbon concentration in the unknown sample is selectively predicted.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: December 16, 2014
    Assignee: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Michael John McLaughlin, Sean Thomas Forrester, Leslie Joseph Janik
  • Publication number: 20140306024
    Abstract: A water delivery device is described which includes an outlet pipe through which water is ejected to provide a water display. A disk is positioned relative to the outlet pipe. The relative positions of the disk and outlet pipe are moved so that the disk is located within the outlet pipe or above it to alter the appearance of the water leaving the outlet pipe. As the relative position of the disk and outlet pipe varies, a sequence of water expressions is provided.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 16, 2014
    Inventors: Mark Fuller, Jim Doyle, Scott Mahlerbee, John McLaughlin
  • Patent number: 8759775
    Abstract: Method for the selective detection of petroleum hydrocarbon in an environmental sample containing natural organic matter. The method includes subjecting the sample to infrared (IR) radiation, and detecting an IR signal centered on a signal at 1380 cm?1, 2690 cm?1, 2730 cm?1, 2830 cm?1, 2870 cm?1, 4164 cm?1, 4256 cm?1, 4329 cm?1 and/or 4388 cm?1. Detection of the IR signal indicates the presence of petroleum hydrocarbon in said sample.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: June 24, 2014
    Assignee: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Sean Thomas Forrester, Michael John McLaughlin, Leslie Joseph Janik
  • Patent number: 8679824
    Abstract: The present disclosure relates to fermentation broth formulations containing organic acids and/or organic acid salts, and methods of making and using such formulations.
    Type: Grant
    Filed: February 19, 2010
    Date of Patent: March 25, 2014
    Assignee: Danisco US Inc.
    Inventors: Tom Tao Huang, Aaron Kelley, John McLaughlin
  • Publication number: 20130280701
    Abstract: The present invention provides an apparatus, system, method and computer program and computer program product for analyzing cellular samples. One embodiment of the apparatus and method provides a multiparameter assay that provides information with respect to cell proliferation, cell cycling and cell death. The multiparameter assay is particularly useful for assessing and screening candidate compounds for anti-cancer utility.
    Type: Application
    Filed: March 1, 2013
    Publication date: October 24, 2013
    Inventors: SUSAN CATALANO, JOHN McLAUGHLIN
  • Patent number: 8412504
    Abstract: The present invention provides an apparatus, system, method and computer program and computer program product for analyzing cellular samples. One embodiment of the apparatus and method provides a multiparameter assay that provides information with respect to cell proliferation, cell cycling and cell death. The multiparameter assay is particularly useful for assessing and screening candidate compounds for anti-cancer utility.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: April 2, 2013
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Susan Catalano, John McLaughlin
  • Patent number: 8410093
    Abstract: The present disclosure provides 2,4-pyrimidinediamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular proliferation and to treat proliferate diseases such as tumorigenic cancers.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: April 2, 2013
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Hui Li, Ankush Argade, Rajinder Singh, Sambaiah Thota, David Carroll, Kin Tso, Vanessa Taylor, John McLaughlin, Vadim Markovtsov
  • Publication number: 20120226653
    Abstract: Disclosed is a method of selectively predicting hydrocarbon concentration in a sample of unknown hydrocarbon concentration (the unknown sample). The method comprises the steps of: (i) separately subjecting two or more samples of known hydrocarbon concentration to infrared (IR) radiation; (ii) separately detecting an IR signal from the samples of known hydrocarbon concentration; (iii) analysing the IR signals using a multivariate chemometric technique to produce a training data set; (iv) generating a predictive model for hydrocarbon concentration based on the training data set; (v) subjecting the unknown sample to infrared (IR) radiation; (vi) detecting an IR signal from the unknown sample; (vii) applying the predictive model to the IR signal from the unknown sample; and thereafter (viii) selectively predicting hydrocarbon concentration in the unknown sample.
    Type: Application
    Filed: September 24, 2010
    Publication date: September 6, 2012
    Inventors: Michael John McLaughlin, Sean Thomas Forrester, Leslie Joseph Janik
  • Publication number: 20120226527
    Abstract: According to some embodiments, a method receives a request for contact information associated with a customer. The method determines a plurality of contact values associated with the customer. The plurality of contact values include a first set of contact values that a first line of business associates with the customer and a second set of contact values that a second line of business associates with the customer. The method determines priority information associated with each contact value. In response to the request for contact information, the method communicates one or more of the contact values. For each contact value being communicated, the method communicates at least some of the priority information associated with the each contact value being communicated.
    Type: Application
    Filed: March 2, 2011
    Publication date: September 6, 2012
    Applicant: BANK OF AMERICA CORPORATION
    Inventors: Dennis Wayne Carwile, JR., Mathew Timothy Roe, Adam Anthony DiCaprio, Gregory Vincent Permar, Scott Stephen Thomas, Michael John O'Brien, Larry Ray Densmore, Edward Elias Arciniega, Helen Ramsey Noles, Kellie Marie Basher, Ryan Scott Heller, Robert John McLaughlin, Jennifer Leigh McCain, Melodee Coleman, Jeanne Carole Edwards, Dan R. Miller, Stephen Mark Schneeweis, Harold Cooper Keener
  • Publication number: 20120219519
    Abstract: The invention relates to the use of a by-product from drinking water treatment, namely alum sludge, in a method and composition for the stabilisation of contaminants (e.g. arsenic and polycyclic aromatic hydrocarbon) in materials such as soils and other solid or semi-solid matrix types. The composition may also comprise a reactive carbon material such as activated carbon. Further, the composition may comprise a solidifier such as calcium silicate-based cement to enable the stabilisation and immobilisation of contaminants.
    Type: Application
    Filed: September 30, 2010
    Publication date: August 30, 2012
    Inventor: Michael John McLaughlin
  • Patent number: 8222480
    Abstract: Compositions and methods are provided for the efficient and reproducible generation of clone animals of all developmental stages. Also provided are methods of use of the same in reproductive and therapeutic cloning protocols.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: July 17, 2012
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Michele Boiani, Kenneth John McLaughlin, Hans R. Schöler, Sigrid Eckardt
  • Publication number: 20120153160
    Abstract: Disclosed herein is a use and a method for the detection of petroleum hydrocarbon in a sample. The method comprises the steps of subjecting the sample to infrared (IR) radiation, and detecting an IR signal in the range of 1360 cm?1 to 2090 cm?1 and/or 2650 cm?1 to 3000 cm?1 and/or 3700 cm?1 to 4400 cm?1. In a particular application, the invention provides a method for the detection of petroleum hydrocarbon in an environmental sample such as soil, silt, sediment, rock, mineral or waste sample.
    Type: Application
    Filed: June 25, 2010
    Publication date: June 21, 2012
    Inventors: Sean Thomas Forrester, Michael John McLaughlin, Leslie Joseph Janik
  • Publication number: 20120059595
    Abstract: The present invention provides an apparatus, system, method and computer program and computer program product for analyzing cellular samples. One embodiment of the apparatus and method provides a multiparameter assay that provides information with respect to cell proliferation, cell cycling and cell death. The multiparameter assay is particularly useful for assessing and screening candidate compounds for anti-cancer utility.
    Type: Application
    Filed: August 26, 2011
    Publication date: March 8, 2012
    Inventors: Susan Catalano, John McLaughlin
  • Publication number: 20120015422
    Abstract: The present disclosure relates to fermentation broth formulations containing organic acids and/or organic acid salts, and methods of making and using such formulations.
    Type: Application
    Filed: February 19, 2010
    Publication date: January 19, 2012
    Inventors: Tom Tao Huang, Aaron Kelley, John Mclaughlin
  • Patent number: 8032346
    Abstract: The present invention provides an apparatus, system, method and computer program and computer program product for analyzing cellular samples. One embodiment of the apparatus and method provides a multiparameter assay that provides information with respect to cell proliferation, cell cycling and cell death. The multiparameter assay is particularly useful for assessing and screening candidate compounds for anti-cancer utility.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: October 4, 2011
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Susan Catalano, John McLaughlin
  • Publication number: 20110169937
    Abstract: Certain aspects of this disclosure relate to a screening method. In general terms, the screening assay comprises contacting test cells with a test compound to provide contacted test cells, obtaining values for a plurality of cytological attributes of the contacted test cells, and scoring the cells using the values to provide a likelihood score for at least one of a plurality of classifiers, where the plurality of classifiers are defined using values for cytological attributes obtained from cells that have been contacted with compounds of known mode of action.
    Type: Application
    Filed: January 5, 2011
    Publication date: July 14, 2011
    Inventors: John McLaughlin, Zachary Pincus, Jim Bernstein
  • Patent number: 7970549
    Abstract: The present invention provides an apparatus, system, method and computer program and computer program product for analyzing cellular samples. One embodiment of the apparatus and method provides a multiparameter assay that provides information with respect to cell proliferation, cell cycling and cell death. The multiparameter assay is particularly useful for assessing and screening candidate compounds for anti-cancer utility.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: June 28, 2011
    Assignee: Rigel Pharmaceuticals Inc.
    Inventors: Susan Catalano, John McLaughlin
  • Publication number: 20110152518
    Abstract: The present disclosure provides 2,4-pyrimidinediamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular proliferation and to treat proliferate diseases such as tumorigenic cancers.
    Type: Application
    Filed: November 22, 2010
    Publication date: June 23, 2011
    Applicant: RIGEL PHARMACEUTICALS, INC.
    Inventors: Hui Li, Ankush Argade, Rajinder Singh, Sambaiah Thota, David Carroll, Kin Tso, Vanessa Taylor, John McLaughlin, Vadim Markovtsov
  • Publication number: 20110123968
    Abstract: A hand-held educational game includes: a transparent container having an inner surface; a receptacle on the inner surface; a text message on the inner surface associated with the receptacle; and an object, moveable by the user, adapted to associate with the receptacle. The user views the device and text through the container and manipulates the container so as to associate the object with the receptacle.
    Type: Application
    Filed: November 24, 2009
    Publication date: May 26, 2011
    Inventor: Corey John McLaughlin
  • Publication number: 20110061129
    Abstract: Provided are transgenic plants, seed and plant parts which display increased resistance to fungal disease or mycotoxin. Also provided are methods of making transgenic plants with increased resistance to fungal disease or mycotoxin.
    Type: Application
    Filed: March 2, 2009
    Publication date: March 10, 2011
    Applicant: RUTGERS, THE STATE UNIVERSITY
    Inventors: Nilgun E. Tumer, Mohamed Anwar Bin Umer, John McLaughlin