Patents by Inventor John A. Moon

John A. Moon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10434169
    Abstract: The present invention relates to methods and compositions for use in inducing tumor-specific antibody mediated complement-dependent cytotoxic response in an animal having a tumor comprising administering to said animal a composition comprising a replication competent oncolytic virus wherein administration of the composition induces in the animal production of antibodies that mediate a CDC response specific to said tumor.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: October 8, 2019
    Assignees: SILLAJEN, INC, SILLAJEN BIOTHERAPEUTICS, INC.
    Inventors: David Kirn, John Bell, Caroline Breitbach, Anne Moon, Tae-Ho Hwang, Yu Kyoung Lee, Mi-kyung Kim
  • Patent number: 10428367
    Abstract: A portable detector is disclosed for detecting certain analytes of interest, such as genetic material (e.g., nucleic acids). The detector includes a reading component for the detection of the analytes, and control circuitry for controlling operation of the reading component. Processing circuitry may be included to perform both primary analysis of acquired data, and where desired, secondary analysis. Where desired, some or all of the computationally intensive tasks may be off-loaded to enhance the portability and speed of the device. The device may incorporate various types of interface, technologies for reading and analysis, positioning system interfaces, and so forth. A number of exemplary use cases and methods are also disclosed.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: October 1, 2019
    Assignee: ILLUMINA, INC.
    Inventors: Robert C. Kain, Min-Jui Richard Shen, John A. Moon, Helmy A. Eltoukhy
  • Publication number: 20190285233
    Abstract: The present disclosure relates to LED lighting that can be used for retrofit applications. In some examples, an LED light source is attached to a heat sink assembly. A housing assembly includes an LED driver connected to the LED light source. A mounting bracket is attached to an anterior of the heat sink assembly and to an anterior plate of the housing assembly.
    Type: Application
    Filed: June 4, 2019
    Publication date: September 19, 2019
    Inventors: Brian Moon, John Luhrs
  • Publication number: 20190251841
    Abstract: An exemplary parking facilitation system includes a plurality of parking space devices disposed at different parking spaces within a parking area and a parking management system configured to control operation of, and to exchange data with, the parking space devices. Each of the parking space devices respectively includes a processor, a vehicle presence detector configured to determine whether any vehicle is parked in a parking space at which the parking space device is disposed, and a parking availability indicator configured to visually indicate an availability status of the parking space. The parking availability indicator is positioned at a height greater than that of any vehicle that the parking space is configured to accommodate so as to be concurrently visible, with parking availability indicators of other parking space devices, from various locations within the parking area at which drivers attempting to locate available parking spaces are to be located.
    Type: Application
    Filed: February 15, 2018
    Publication date: August 15, 2019
    Inventors: Umesh Saraki Munireddy, Anil Kumar, Alin D'Silva, Alan T. Hopper, Gunjan Desai, Radoslaw Wilk, John R. Canada, Heedoo Moon, Chethan Makam
  • Publication number: 20190219835
    Abstract: Example super-resolution microscopy systems are described herein that are configured for relatively high throughput. The disclosed microscopy systems can be to generate an array of sub-diffraction activated areas for imaging. The microscopy systems can be to utilize imaging techniques that employ time delay integration to build up super-resolution images over time. The disclosed microscopy systems can utilize long-lived fluorophores in conjunction with wide field and patterned illumination to generate super-resolution images of a sample with relatively high throughput.
    Type: Application
    Filed: June 20, 2017
    Publication date: July 18, 2019
    Inventors: Gary Mark SKINNER, Geraint Wyn EVANS, Stanley S. HONG, John A. MOON, M. Shane BOWEN, Jonathan Mark BOUTELL, Jasori Richard BETLEY
  • Patent number: 10344926
    Abstract: The modular LED retrofit lamp system includes a high-power LED light engine, together with an integrated optics mount, an integrated yet serviceable LED dimmable driver, and a point of attachment on the center area of the engine for mounting the LED engine. Different mounts for the engine can include, but are not limited to, PAR56, PAR46, PAR64, PAR38, Mini Candelabra, Intermediate Screw Base, Mogul Screwbase, and Fresnel-based Theatrical Fixtures. One LED light engine can replace a wide range of tungsten lamps ranging up to 500 watt equivalents in output performance, as well as dimming performance. Additional brackets and lamp sockets easily retrofit into an existing lighting fixture, while dimming capabilities are retained.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: July 9, 2019
    Inventors: Brian Moon, John Luhrs
  • Patent number: 10306188
    Abstract: A photographic image exchange system includes an imaging device having an imager that performs imaging, a communicator that performs communication with a server, and a controller that controls the communicator such that an image that includes a registered target among images captured by the imager is transmitted to the server, and the server provides the image received from the imaging device to a device used by a user who is related to the registration.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: May 28, 2019
    Assignee: Honda Motor Co., Ltd.
    Inventors: Tamotsu Kawamura, Kotaro Shigeno, Hiroshi Akiyama, Masaki Negoro, Yoshinori Matsuo, Naoki Sugimoto, Dennis Clark, John Moon
  • Patent number: 10304189
    Abstract: Methods and systems for analysis of image data generated from various reference points. Particularly, the methods and systems provided are useful for real time analysis of image and sequence data generated during DNA sequencing methodologies.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: May 28, 2019
    Assignee: Illumina, Inc.
    Inventors: Francisco Garcia, Klaus Maisinger, Stephen Tanner, John Moon, Tobias Mann, Michael Lawrence Parkinson, Anthony James Cox, Haifang H. Ge
  • Publication number: 20190153519
    Abstract: A method for scanning a microarray, including (a) providing a microarray to an optical scanner, wherein the microarray includes a surface having features having different target molecules; (b) scanning the surface in the x or y direction to acquire optical signals from the features at sequential regions of the surface, wherein the focus setting between the optical scanner and the surface is dynamically controlled in real time by repeatedly (i) adding a predetermined focal offset, thereby introducing an error in the focus setting, and (ii) adjusting the focus setting to reduce the error in the focus setting, thereby acquiring the optical signals from different regions at different degrees of focus such that a subset of the regions that are scanned have an introduced focus error; and (c) analyzing the optical signals that are obtained at the different degrees of focus to identify the different target molecules.
    Type: Application
    Filed: January 18, 2019
    Publication date: May 23, 2019
    Inventors: Darren Robert Segale, John Moon, Hongji Ren
  • Patent number: 10227636
    Abstract: A method for scanning a microarray, including (a) providing a microarray to an optical scanner, wherein the microarray includes a surface having features having different target molecules; (b) scanning the surface in the x or y direction to acquire optical signals from the features at sequential regions of the surface, wherein the focus setting between the optical scanner and the surface is dynamically controlled in real time by repeatedly (i) adding a predetermined focal offset, thereby introducing an error in the focus setting, and (ii) adjusting the focus setting to reduce the error in the focus setting, thereby acquiring the optical signals from different regions at different degrees of focus such that a subset of the regions that are scanned have an introduced focus error; and (c) analyzing the optical signals that are obtained at the different degrees of focus to identify the different target molecules.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: March 12, 2019
    Assignee: ILLUMINA, INC.
    Inventors: Darren Robert Segale, John A. Moon, Hongji Ren
  • Publication number: 20190001328
    Abstract: A method of making a flowcell includes bonding a first surface of an organic solid support to a surface of a first inorganic solid support via a first bonding layer, wherein the organic solid support includes a plurality of elongated cutouts. The method further includes bonding a surface of a second inorganic solid support to a second surface of the organic solid support via a second bonding layer, so as to form the flowcell. The formed flowcell includes a plurality of channels defined by the surface of the first inorganic solid support, the surface of the second inorganic solid support, and walls of the elongated cutouts.
    Type: Application
    Filed: July 3, 2018
    Publication date: January 3, 2019
    Inventors: Jeffrey S. Fisher, John A. Moon, Bala Murali Venkatesan
  • Publication number: 20180178215
    Abstract: A fluidic device including an inorganic solid support attached to an organic solid support by a bonding layer, wherein the inorganic solid support has a rigid structure and wherein the bonding layer includes a material that absorbs radiation at a wavelength that is transmitted by the inorganic solid support or the organic solid support; and a channel formed by the inorganic solid support and the organic solid support, wherein the bonding layer that attaches the inorganic solid support to the organic solid support provides a seal against liquid flow. Methods for making fluidic devices, such as this, are also provided.
    Type: Application
    Filed: February 22, 2018
    Publication date: June 28, 2018
    Applicant: ILLUMINA, INC.
    Inventors: Jeffrey S. FISHER, John A. MOON, Bala Murali VENKATESAN
  • Patent number: 9982294
    Abstract: A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b) extending a first primer bound to the first template using a first polymerase species and a first set of nucleotide analogs; (c) extending a second primer bound to the second template using a second polymerase species and a second set of nucleotide analogs, wherein the first polymerase species is different from the second polymerase species and wherein the first set of nucleotide analog is different from the second set of nucleotide analog, (d) detecting the first and second primer extension products; and (e) repeating steps (b) through (d), thereby determining the different sequences of the first and second templates.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: May 29, 2018
    Assignee: ILLUMINA, INC.
    Inventors: Martin Maria Fabani, Maria Candelaria Rogert Bacigalupo, John A. Moon
  • Publication number: 20170274374
    Abstract: An array including a solid support having a plurality of contours along its exterior surface. A first subset of contours is positioned along the exterior surface of the solid support to form a first pattern of features and a second subset of contours is positioned along the exterior surface to form a second pattern of features. The contours of the first subset are juxtaposed with the second subset along the exterior surface, whereby the first and second patterns form an interleaved pattern. The features of the first pattern occur at a first elevation z1 and the features of the second pattern occur at a second elevation z2. The features of the first pattern are configured to attach analytes at a different elevation relative to analytes attached to the features of the second pattern.
    Type: Application
    Filed: March 28, 2017
    Publication date: September 28, 2017
    Inventors: M. Shane Bowen, Michael Graige, Stanley S. Hong, John A. Moon, Merek Siu
  • Publication number: 20170246635
    Abstract: A detection apparatus having a read head including a plurality of microfluorometers positioned to simultaneously acquire a plurality of the wide-field images in a common plane; and (b) a translation stage configured to move the read head along a substrate that is in the common plane. The substrate can be a flow cell that is included in a cartridge, the cartridge also including a housing for (i) a sample reservoir; (ii) a fluidic line between the sample reservoir and the flow cell; (iii) several reagent reservoirs in fluid communication with the flow cell, (iv) at least one valve configured to mediate fluid communication between the reservoirs and the flow cell; and (v) at least one pressure source configured to move liquids from the reservoirs to the flow cell. The detection apparatus and cartridge can be used together or independent of each other.
    Type: Application
    Filed: May 12, 2017
    Publication date: August 31, 2017
    Inventors: Dale Buermann, John A. Moon, Bryan Crane, Mark Wang, Stanley S. Hong, Jason Harris, Matthew Hage, Mark J. Nibbe
  • Publication number: 20170208294
    Abstract: A photographic image replacement system includes an imaging device having an imager that performs imaging, a communicator that performs communication with a server, and a controller that controls the communicator such that an image that includes a registered target among images captured by the imager is transmitted to the server, and the server provides the image received from the imaging device to a device used by a user who is related to the registration.
    Type: Application
    Filed: June 9, 2015
    Publication date: July 20, 2017
    Inventors: Tamotsu KAWAMURA, Kotaro SHIGENO, Hiroshi AKIYAMA, Masaki NEGORO, Yoshinori MATSUO, Naoki SUGIMOTO, Dennis CLARK, John MOON
  • Publication number: 20170159118
    Abstract: A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b) extending a first primer bound to the first template using a first polymerase species and a first set of nucleotide analogs; (c) extending a second primer bound to the second template using a second polymerase species and a second set of nucleotide analogs, wherein the first polymerase species is different from the second polymerase species and wherein the first set of nucleotide analog is different from the second set of nucleotide analog, (d) detecting the first and second primer extension products; and (e) repeating steps (b) through (d), thereby determining the different sequences of the first and second templates.
    Type: Application
    Filed: February 17, 2017
    Publication date: June 8, 2017
    Applicant: Illumina, Inc.
    Inventors: Martin Maria Fabani, Maria Candelaria Rogert Bacigalupo, John A. Moon
  • Publication number: 20170161900
    Abstract: Methods and systems for analysis of image data generated from various reference points. Particularly, the methods and systems provided are useful for real time analysis of image and sequence data generated during DNA sequencing methodologies.
    Type: Application
    Filed: November 17, 2016
    Publication date: June 8, 2017
    Inventors: Francisco Garcia, Klaus Maisinger, Stephen Tanner, John Moon, Tobias Mann, Michael Lawrence Parkinson, Anthony James Cox, Haifang H. Ge
  • Patent number: 9650669
    Abstract: A detection apparatus having a read head including a plurality of microfluorometers positioned to simultaneously acquire a plurality of the wide-field images in a common plane; and (b) a translation stage configured to move the read head along a substrate that is in the common plane. The substrate can be a flow cell that is included in a cartridge, the cartridge also including a housing for (i) a sample reservoir; (ii) a fluidic line between the sample reservoir and the flow cell; (iii) several reagent reservoirs in fluid communication with the flow cell, (iv) at least one valve configured to mediate fluid communication between the reservoirs and the flow cell; and (v) at least one pressure source configured to move liquids from the reservoirs to the flow cell. The detection apparatus and cartridge can be used together or independent of each other.
    Type: Grant
    Filed: July 18, 2014
    Date of Patent: May 16, 2017
    Assignee: Illumina, Inc.
    Inventors: Dale Buermann, John A. Moon, Bryan Crane, Mark Wang, Stanley S. Hong, Jason Harris, Matthew Hage, Mark J. Nibbe
  • Patent number: 9574235
    Abstract: A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b) extending a first primer bound to the first template using a first polymerase species and a first set of nucleotide analogs; (c) extending a second primer bound to the second template using a second polymerase species and a second set of nucleotide analogs, wherein the first polymerase species is different from the second polymerase species and wherein the first set of nucleotide analog is different from the second set of nucleotide analog, (d) detecting the first and second primer extension products; and (e) repeating steps (b) through (d), thereby determining the different sequences of the first and second templates.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: February 21, 2017
    Assignee: ILLUMINA, INC.
    Inventors: Martin Maria Fabani, Maria Candelaria Rogert Bacigalupo, John A. Moon