Abstract: Processor-guided execution of offloaded instructions using fixed function operations is disclosed. Instructions designated for remote execution by a target device are received by a processor. Each instruction includes, as an operand, a target register in the target device. The target register may be an architected virtual register. For each of the plurality of instructions, the processor transmits an offload request in the order that the instructions are received. The offload request includes the instruction designated for remote execution. The target device may be, for example, a processing-in-memory device or an accelerator coupled to a memory.

Abstract: Systems and methods for pushed prefetching include: multiple core complexes, each core complex having multiple cores and multiple caches, the multiple caches configured in a memory hierarchy with multiple levels; an interconnect device coupling the core complexes to each other and coupling the core complexes to shared memory, the shared memory at a lower level of the memory hierarchy than the multiple caches; and a push-based prefetcher having logic to: monitor memory traffic between caches of a first level of the memory hierarchy and the shared memory; and based on the monitoring, initiate a prefetch of data to a cache of the first level of the memory hierarchy.

Abstract: The disclosure relates to certain uses and methods of use of 3.1.0 and 4.1.0 azabicycle compounds of Formula (I), wherein X, Y, R1, R2a, and R2b are defined herein, and pharmaceutical compositions containing them, in the treatment of autism spectrum disorder, including Asperger's syndrome.

Abstract: A gripper assembly (20) includes a cylinder (22), a deformable gripping portion (210), a piston (24), and an ejector (260). The gripper assembly is suitable for picking and placing a vessel (10) by gripping a gripped portion (102) of the vessel. The gripping portion extends from adjacent an end of the cylinder. The gripping portion has a spring-like property that allows deformation as the vessel is engaged thereby holding the vessel. The piston is slidably disposed inside the cylinder. The ejector includes a head portion (270) adjacent a first end of the ejector and a plunger portion (26) adjacent a second end of the ejector. The head portion of the ejector is slidably disposed inside the cylinder separately from the piston. The plunger of the ejector is partially disposed within the deformable gripping portion for engaging the vessel. The gripper assembly may be used to align an analyzer instrument (800).

Abstract: The present invention is related to a plant biostimulant adjuvant and a method of treating a crop with a plant biostimulant adjuvant. The plant biostimulant adjuvant comprises a plant biostimulant comprising at least one of an amino acid or a peptide derived from a plant source. The plant biostimulant adjuvant also comprises an alkyl amine alkoxylate defined by the formula: wherein: R1 is an alkyl of 6 to 22 carbons; each R2 and R3 are each independently H or CH3. n and m are each at least one and taken together n+m is 5 to 25; and water.

Abstract: The present invention is directed to novel sulfamide derivatives, pharmaceutical compositions comprising said compounds and methods for the treatment of epilepsy and related disorders comprising administering to a subject in need thereof, said compounds, either alone or as co-therapy with one or more anticonvulsant and/or anti-epileptic agents.

Abstract: The present invention is directed to novel sulfamide derivatives, pharmaceutical compositions comprising said compounds and methods for the treatment of epilepsy and related disorders comprising administering to a subject in need thereof, said compounds, either alone or as co-therapy with one or more anticonvulsant and/or anti-epileptic agents.

Abstract: An infeed device provides a configuration that improves the flow of particulate material into a double wash deck dedusting apparatus. The infeed device is formed with a circular inlet opening, an oval-shaped discharge opening and step sides interconnecting the inlet and discharge openings to prevent bridging in particulate material being fed through the infeed device onto the wash decks. The infeed device can be formed as a separate member that can be inserted into the infeed opening of existing dedusters. The oval-shaped discharge opening is substantially smaller transversely than the diameter of the inlet opening, but has a longitudinal length that is equal to the diameter of the inlet opening and equal to the longitudinal length of the wash decks. The joinder of the wash decks is blunted to eliminate a divider edge on which plastic streamers can hang up while being fed to the wash decks.

Abstract: Adatanserin is useful for treating neurodegenerative disorders, chronic pain, and other disorders associated with dysfunctional glutamate release. Methods of treating the same comprise administering a therapeutically effective amount of adatanserin or a pharmaceutical salt thereof, to a patient in need of said treatment.

Abstract: This invention provides a method of treating pain in a mammal that includes administering to a mammal in need of such treatment a pain treating effective amount of a compound of the formula (I): where R1 is H, alkyl or phenylalkyl; R2 is H, alkyl, alkenyl or phenylalkyl; or R1 and R2 taken together as Z are —CH2C—H2—, —CH2C(R6)(R7)CH2— or —CH2C(R8)(R9)—C(R10)(R11)CH2—, where R6, R8 and R10 are, independently, H, alkyl or hydroxyl and R7, R9 and R11 are, independently, H or alkyl; A is alkylene or alkenylene; X is CO2R3, P(O)(OR4)(OR5), 3,5-dioxo-1,2,4-oxadiazolidin-2-yl or 5-tetrazolyl in which R3, R4 and R5 are, independently, H or alkyl, or a pharmaceutically acceptable salt thereof. The present invention also provides pharmaceutical compositions for treating pain containing a pain treating effective amount of the compound of formula (I).

Abstract: A system for acquiring information on the operation of an electronic control unit (ECU) includes a controller and a non-volatile memory. The controller is coupled to address and data buses of a central processing unit (CPU), which is located within an electronic control unit (ECU). The controller includes a register and/or a logging buffer for facilitating ECU analysis. The non-volatile memory is located within the ECU and is coupled to the address and data buses of the CPU. The register logs the current memory address of the non-volatile memory, when the controller determines the current memory address is a memory address of interest. The logging buffer logs the current memory address of the non-volatile memory each time the controller determines the current memory address is a memory address of interest.

Abstract: An antipsychotic and GlyT1 inhibitor combination is disclosed. The antipsychotic and GlyT1 inhibitor combination may be employed in the prevention and treatment of symptoms of schizophrenia. Pharmaceutical compositions and treatments comprising an antipsychotic and a GlyT1 inhibitor for treating symptoms of schizophrenia are thus also disclosed.

Abstract: An alarm system, security container, and kit. The alarm system includes a base having a top surface, a bottom surface, and an opening therethrough, a rod dimensioned to pass through the opening through the base, and an anchor is attached to the rod and disposed below the bottom surface of the base. An actuator is attached to the rod and disposed above the top surface of the base and a primary switch is attached to the top surface of the base proximate to the actuator. The primary switch includes a switch trigger adapted to communicate with the actuator and turn the primary switch from an off position to an on position when the base is moved upward. A power source is in electrical communication with the switch and an audible alarm in electrical communication with the switch.

Abstract: Adatanserin is useful for treating neurodegenerative disorders, chronic pain, and other disorders associated with dysfunctional glutamate release. Methods of treating the same comprise administering a therapeutically effective amount of adatanserin or a pharmaceutical salt thereof, to a patient in need of said treatment.

Abstract: Adatanserin is useful for treating neurodegenerative disorders, chronic pain, and other disorders associated with dysfunctional glutamate release. Methods of treating the same comprise administering a therapeutically effective amount of adatanserin or a pharmaceutical salt thereof, to a patient in need of said treatment.

Abstract: This invention provides a method of inducing cognition enhancement in a mammal by administering to the mammal experiencing a cognition impairment an effective amount of a hydroxycycloalkanephenethyl amine compound of the following structural formula: ##STR1## in which A is a moiety of the formula ##STR2## wherein the dotted line represents optional unsaturation;R.sub.1 is hydrogen or alkyl;R.sub.2 is alkyl;R.sub.4 is hydrogen, alkyl, formyl, or alkanol;R.sub.5 and R.sub.6 are, independently, hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, dialkylamino, alkanamido, halo, trifluoromethyl, or taken together, methylene dioxy;R.sub.7 is hydrogen or alkyl; andn is 0, 1, 2, 3, or 4;or a pharmaceutically acceptable salt thereof.

Abstract: There are disclosed the use of the compounds of the formula (I) ##STR1## wherein R.sup.1 is 1-adamantyl, 3-methyl-1-adamantyl, 3-noradamantyl, unsubstituted or substituted-2-indolyl, 3-indolyl, 2-benzofuranyl or 3-benzofuranyl wherein the substituents are selected from lower alkyl, lower alkoxy and halo; R.sup.2 is unsubstituted or substituted phenyl, benzyl, or pyrimidinyl wherein the substituents are selected from lower alkyl, lower alkoxy, trifluoromethyl and halo; R.sup.3 is H or lower alkyl of 1 to 3 carbon atoms; n is the integer 0 or 1; and m is the integer from 2 to 5 and the pharmaceutically acceptable salts thereof.

Abstract: In a process for preparing a coated microwaveable meat which will be juicy and tender after microwave cooking, the meat is intimately contacted with an aqueous solution having a pH of 5.0-9.0 and a cation normality ratio of Na.sup.+ /K.sup.+ /Ca.sup.++ of 2-10/1-6/1-4, the contact continuing until the water gain in the meat is at least 8% of the initial weight of the meat. Thereafter a dry, powdery coating agent, including starch, protein and optional flavoring, is applied to the meat. During subsequent microwave cooking of the meat, the coating agent forms a starch-and-protein crosslinked continuous skin-like film which controls the heating rate and the microwave penetration depth so that microwave energy absorption is at least initially higher at the film than in the interior of the meat.

Abstract: A fry-like microwave cooking process for producing food with a crisp exterior and a soft, tender interior includes the steps of applying an edible hydrophilic lossy susceptor to at least a portion of the surface of the food bearing a moisture-retardant edible barrier layer, and microwave cooking the susceptor-bearing food to provide a crisp exterior and a soft, tender interior for the food. The barrier layer is a natural skin, a dough layer or a film formed of a plasticized material selected from the group consisting of methylcellulose, carrageenan and combinations thereof. The susceptor includes glycerine, sucrose ester, and chloride salt. The susceptor is characterized by the property that 25 grams of the susceptor in a 50 ml. glass beaker is heatable to 200.degree. C. in less than 40 seconds by 900 watts of microwave energy in a 1.1 cu. ft. oven. Preferably the process further browns and crisps the food exterior through a Maillard reaction at a temperature of at least 135.degree. C.

Abstract: There are disclosed the use of the compounds of the formula (I) ##STR1## wherein R.sup.1 is 1-adamantyl, 3-methyl-1-adamantyl, 3-noradamantyl, unsubstituted or substituted-2-indolyl, 3-indolyl, 2-benzofuranyl or 3-benzofuranyl wherein the substituents are selected from lower alkyl, lower alkoxy and halo; R.sup.2 is unsubstituted or substituted phenyl, benzyl, or pyrimidinyl wherein the substituents are selected from lower alkyl, lower alkoxy, trifluoromethyl and halo; R.sup.3 is H or lower alkyl of 1 to 3 carbon atoms; n is the integer 0 or 1; and m is the integer from 2 to 5 and the pharmaceutically acceptable salts thereof.