Abstract: A device may receive a first type of data identifying measurements associated with user devices and/or base stations of a mobile radio environment, and a second type of data identifying spatiotemporal behavior associated with the user devices. The device may train a first model, with the first type of data, to generate a trained first model that yields dimensionality-reduced spatiotemporal characteristics of the first type of data, and may train a second model, with the second type of data and the dimensionality-reduced spatiotemporal characteristics, to generate a trained second model. The device may receive particular data identifying measurements associated with a user device and/or base stations, and may process the particular data, with the trained first model, to generate a dimensionality-reduced spatiotemporal characteristic of the particular data.

Abstract: An online system generates and stores virtual models of physical spaces. These virtual models represent physical objects within the physical spaces through 3D representations of those objects. A content development system can request a virtual model associated with a physical space and modify the virtual model to include virtual objects. The content development system transmits the modified virtual model to be stored by the online system. A client device requests the modified virtual model from the online system when the client device is posed near the physical space. The client device uses the modified virtual model to display a modified video feed that displays the virtual content generated by the content development system as an augmented reality experience.

Abstract: A sheath assembly for the insertion of a percutaneous pump includes a tubular sheath body dimensioned for insertion into a blood vessel through a vessel aperture. The tubular sheath body includes a wall having a proximal end portion, a distal end portion, a longitudinal axis, an outer surface, an inner surface defining a first lumen substantially parallel to the longitudinal axis, and a second lumen disposed within the wall between the inner surface and the outer surface and extending from the proximal end portion to the distal end portion. The first lumen is dimensioned to allow passage of a portion of the percutaneous pump, and the second lumen is dimensioned for passage of a guidewire. A stylet is removably positioned to substantially occlude the second lumen. The stylet has a proximal end releasably secured to the sheath assembly.

Abstract: The present disclosure includes kits, compositions, and methods useful in medical procedures, such as treating a fistula or other target site of a subject. In some examples, the kit may comprise a dry particulate mixture, a first pharmaceutically acceptable buffer solution having a pH ranging from about 3 to about 5, and a second pharmaceutically acceptable buffer solution having a pH ranging from about 9 to about 11. The dry particulate mixture may comprise a plurality of polyethylene glycol particles and a plurality of collagen particles.

Abstract: Stents and/or implants including a reinforcement member. An illustrative transluminal implant may include an elongated tubular body extending from first end region to a second end region. The elongated tubular body may comprise a scaffolding forming a plurality of cells, a first flange adjacent to the first end region, a second flange adjacent to the second end region, and a saddle region extending between the first flange and the second flange. The saddle region may have an outer diameter less than an outer diameter of the first flange and the second flange. A reinforcement member may be disposed within a lumen of the elongated tubular body and within the first flange.

Abstract: A tissue anchor system is provided that includes a first tissue anchor, a second tissue anchor that is separate and distinct from the first tissue anchor, and one or more tethers, which are configured to couple the first tissue anchor to the second tissue anchor. When the first tissue anchor is unconstrained, a head thereof is coaxial with an axis of a shaft thereof, and a tissue-coupling element thereof extends from a distal end of the shaft, is generally orthogonal to the axis, and is shaped such that if the tissue-coupling element were to be projected onto a plane that is perpendicular to the axis, at least 80% of an area of a projection of the tissue-coupling element on the plane would fall within a first angle of 180 degrees in the plane having a vertex at the axis. Other embodiments are also described.

Abstract: Systems, devices, media and methods are presented for presentation of modified objects within a video stream. The systems and methods select an object of interest depicted within a user interface based on an associated image modifier, determine a modifier context based at least in part on one or more characteristics of the selected object, identify a set of image modifiers based on the modifier context, rank a first portion of the identified set of image modifiers based on a primary ordering characteristic, rank a second portion of the identified set of image modifiers based on a secondary ordering characteristic and cause presentation of the modifier icons for the ranked set of image modifiers.

Abstract: A hinged support apparatus that can include a mounting plate, an elongated base, and two living hinges on the elongated base. The mounting plate can have a proximal and a distal end. The elongated base can have a proximal end, a midway point, and a distal end, wherein the proximal end of the elongated base can be attached to at least a portion of the proximal end of the mounting plate and the midway point can create a proximal half and a distal half of the elongated base. A first of the two living hinges can be located between the proximal end and the midway point of the elongated base. A second of the two living hinges can be located between the first living hinge and the midway point of the elongated base. The two living hinges can be parallel to each other and can pivot in the same direction.

Abstract: An actuation pressure to actuate one or more hydraulic actuators may be determined based on a load on the one or more hydraulic actuators of a robotic device. Based on the determined actuation pressure, a pressure rail from among a set of pressure rails at respective pressures may be selected. One or more valves may connect the selected pressure rail to a metering valve. The hydraulic drive system may operate in a discrete mode in which the metering valve opens such that hydraulic fluid flows from the selected pressure rail through the metering valve to the one or more hydraulic actuators at approximately the supply pressure. Responsive to a control state of the robotic device, the hydraulic drive system may operate in a continuous mode in which the metering valve throttles the hydraulic fluid such that the supply pressure is reduced to the determined actuation pressure.

Abstract: Provided herein are compositions and methods for the treatment of a cancer. Said compositions comprise an FGFR kinase inhibitor. Some embodiments comprise combination therapy featuring the FGFR kinase inhibitor with at least one oncology therapeutic agent.

Abstract: A reference electrode assembly for electrochemistry microscopy samples includes a Micro-Electro-Mechanical Systems (MEMS) chip having a thin-film wire disposed on a surface thereof, a bridge electrode electrically connected to the thin-film wire through a Transmission Electron Microscope (TEM) holder, a portion of the bridge electrode disposed in contact with a sample solution contained within a vial and a standard reference electrode disposed within the vial and in contact with the sample solution, wherein the standard reference electrode electrically connects to a potentiostat maintaining the charge balance with a sample solution. The MEMS chip may be disposed within a holder tip connected with the TEM holder at an end thereof. A portion of the reference electrode assembly may be disposed within a Faraday cage to minimize the effect of noise on the reference potential.

Abstract: A robotic catheter procedure system includes a bedside system that has a percutaneous device, and an actuating mechanism configured to engage and to impart movement to the percutaneous device. The system also includes a workstation coupled to the bedside system. The workstation includes a user interface configured to receive a user input, ma display device configured to display an image, a control system operatively coupled to the user interface and the actuating mechanism. The control system is configured to generate a control signal and the actuating mechanism causes movement of the percutaneous device in response to the control signal. The control system is configured to slow movement of the percutaneous device via the actuating mechanism as an identified point on the percutaneous device approaches a structure requiring a change in direction of the percutaneous device.

Abstract: An internet service provider (ISP) is configured to analyze a subscriber's sent e-mail packets to determine a subscriber identity associated with the e-mail packets. A database is then queried to determine a current sending rate of e-mails by the subscriber. A sending rate above an allowed threshold causes the upstream transmission of the e-mail packets to be blocked by injecting connection destroying packets. A subscriber remains blocked from upstream transmission of e-mails until the sending rate as determined by the ISP drops below a second, more stringent threshold. This automatic process is also accompanied by automated messaging to the subscriber with information as to the measures taken and remedial options.

Abstract: A system and method for altering bone growth on and within an orthopedic implant that includes an implant body; a plurality of electrodes, wherein each electrode is at least partially embedded in the implant body, and comprises: a set of primary electrodes comprising at least one electrode, wherein a non-embedded segment of each primary electrode is proximal to a bone growth region, a set of secondary electrodes comprising at least one electrode, wherein a non-embedded segment of each secondary electrode is distal to the bone growth region, and wherein the plurality of electrodes are configured to function in a stimulation operating mode, such that a subset of primary electrodes function as cathodes and a subset of secondary electrodes function as anodes; a control system comprising a processor, and circuitry that connects to the plurality of electrodes; and a power system.

Abstract: A method for providing watermark to subscribers is provided. The method comprises observing a request for a first content from a subscriber, determining if the subscriber can receive a watermark, generating a second content comprising the watermark if the subscriber can receive a watermark, causing the subscriber to fetch the first content, and causing the subscriber to fetch the second content comprising the watermark overlaying the first content.

Abstract: In a set-top-box system, messages from a service provider are stored and delayed until activity from a set-top-box remote is detected. Messages are then generated and provided to a television associated with the set-top-box. Delaying of the message display until set-top-box activity is detected allows short display times, thus preventing burn-in on some television screens, while providing a greater likelihood that messages will be viewed.

Abstract: The disclosed end-to-end product customization systems and methods receive custom orders from customers or consumers, evaluate them, and generate production-ready custom orders that are able to be used by decorator to create the custom products. The system receives a customization option and an order file type in the custom order. The system or a third party evaluates that customization option to identify a change order that is required and also determines a conversion recommendation to convert the order file type or a production-ready file type. The production-ready custom order is generated based on the change order and the conversion recommendation.

Abstract: A stimulation scheduling system includes a control signal generator and a controller, which can form a control loop configured to generate sets of consistent pulse schedules with a controlled degree of difficulty. The control signal generator can generate a set of consistent pulse schedules using a set of corresponding stimulation parameter distributions and provide a detection parameter based on the generation of the set of consistent pulse schedules to a controller. The controller can estimate a difficulty state based on the detection parameter and update the stimulation parameter distributions based on the estimated difficulty state. The controller can model the difficulty of generating sets of consistent pulse schedules using a difficulty distribution. The difficulty state can be a parameter of the difficulty distribution. The controller can balance the difficulty of generating sets of consistent pulse schedules against the fidelity of the generated sets of pulse schedules.