Patents by Inventor John A. Pauly

John A. Pauly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10775466
    Abstract: A system for magnetic resonance imaging an object via a stochastic optimization of a sampling function is provided. The system includes a magnet assembly and a controller. The magnet assembly is operative to acquire MR data from the object. The controller is operative to: acquire a first MR data set using the magnet assembly; select the sampling function from a plurality of sampling function candidates based at least in part on the stochastic optimization; and acquire a second MR data set from the object using the magnet assembly based at least in part on the sampling function.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: September 15, 2020
    Assignee: GE PRECISION HEALTHCARE LLC
    Inventors: Suchandrima Banerjee, Enhao Gong, Greg Zaharchuk, John Pauly
  • Patent number: 10520573
    Abstract: A method for performing wave-encoded magnetic resonance imaging of an object is provided. The method includes applying one or more wave-encoded magnetic gradients to the object, and acquiring MR signals from the object. The method further includes calibrating a wave point-spread function, and reconstructing an image from the MR signals based at least in part on the calibrated wave point-spread function. Calibration of the wave point-spread function is based at least in part on one or more intermediate images generated from the MR signals.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: December 31, 2019
    Assignees: GENERAL ELECTRIC COMPANY, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Feiyu Chen, Tao Zhang, Joseph Y. Cheng, Valentina Taviani, Brian Hargreaves, John Pauly, Shreyas Vasanawala
  • Publication number: 20190250233
    Abstract: A system for magnetic resonance imaging an object via a stochastic optimization of a sampling function is provided. The system includes a magnet assembly and a controller. The magnet assembly is operative to acquire MR data from the object. The controller is operative to: acquire a first MR data set using the magnet assembly; select the sampling function from a plurality of sampling function candidates based at least in part on the stochastic optimization; and acquire a second MR data set from the object using the magnet assembly based at least in part on the sampling function.
    Type: Application
    Filed: February 9, 2018
    Publication date: August 15, 2019
    Applicants: GENERAL ELECTRIC COMPANY, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: SUCHANDRIMA BANERJEE, ENHAO GONG, GREG ZAHARCHUK, JOHN PAULY
  • Publication number: 20180143277
    Abstract: A method for performing wave-encoded magnetic resonance imaging of an object is provided. The method includes applying one or more wave-encoded magnetic gradients to the object, and acquiring MR signals from the object. The method further includes calibrating a wave point-spread function, and reconstructing an image from the MR signals based at least in part on the calibrated wave point-spread function. Calibration of the wave point-spread function is based at least in part on one or more intermediate images generated from the MR signals.
    Type: Application
    Filed: April 7, 2017
    Publication date: May 24, 2018
    Applicants: GENERAL ELECTRIC COMPANY, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: FEIYU CHEN, TAO ZHANG, JOSEPH Y. CHENG, VALENTINA TAVIANI, BRIAN HARGREAVES, JOHN PAULY, SHREYAS VASANAWALA
  • Patent number: 7966053
    Abstract: A method for performing spectroscopy using an interleaved readout for at least two species. A B0 field is applied. A first spatial-spectral (SPSP) position resolved spectroscopy sequence (PRESS) excitation with a sufficiently narrow band to excite a first species without exciting a second species is applied. A first readout that measures the first species is performed. A second SPSP PRESS excitation with a sufficiently narrow band to excite the second species without exciting the first species is applied. A second readout that measures the second species is performed.
    Type: Grant
    Filed: November 26, 2007
    Date of Patent: June 21, 2011
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Priti Balchandani, Daniel Spielman, John Pauly
  • Patent number: 7683618
    Abstract: A manifestation of the invention provides a method for slice selective excitation for magnetic resonance imaging (MRI). A B0 field is applied. A STABLE pulse comprising of a BIR-4 envelope sampled by a plurality of subpulses with a duration is applied, where amplitude and frequency modulation functions of the BIR-4 envelope are slowly varying with respect to the duration of the subpulses. A portion of k-space is read out to obtain k-space data. The STABLE pulse and readout are repeated until sufficient k-space has been acquired. A Fourier Transform of the k-space data is taken.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: March 23, 2010
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Priti Balchandani, Daniel Spielman, John Pauly
  • Publication number: 20090230958
    Abstract: A manifestation of the invention provides a method for slice selective excitation for magnetic resonance imaging (MRI). A B0 field is applied. A STABLE pulse comprising of a BIR-4 envelope sampled by a plurality of subpulses with a duration is applied, where amplitude and frequency modulation functions of the BIR-4 envelope are slowly varying with respect to the duration of the subpulses. A portion of k-space is read out to obtain k-space data. The STABLE pulse and readout are repeated until sufficient k-space has been acquired. A Fourier Transform of the k-space data is taken.
    Type: Application
    Filed: March 13, 2008
    Publication date: September 17, 2009
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Priti Balchandani, Daniel Spielman, John Pauly
  • Publication number: 20090137897
    Abstract: A method for performing spectroscopy using an interleaved readout for at least two species. A B0 field is applied. A first spatial-spectral (SPSP) position resolved spectroscopy sequence (PRESS) excitation with a sufficiently narrow band to excite a first species without exciting a second species is applied. A first readout that measures the first species is performed. A second SPSP PRESS excitation with a sufficiently narrow band to excite the second species without exciting the first species is applied. A second readout that measures the second species is performed.
    Type: Application
    Filed: November 26, 2007
    Publication date: May 28, 2009
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Priti Balchandani, Daniel Spielman, John Pauly
  • Publication number: 20060267584
    Abstract: Methods and systems for generating T1-weighted images are provided. The method includes acquiring a pair of single-shot fast-spin-echo (SSFSE) images S1 and S2. The method further includes generating a T1-weighted image ST1w based on S1 and S2.
    Type: Application
    Filed: May 24, 2005
    Publication date: November 30, 2006
    Inventors: Reed Busse, John Pauly, Greg Zaharchuk
  • Publication number: 20060214660
    Abstract: Banding artifacts in steady state free precession (SSFP) magnetic resonance imaging (MRI) are reduced by acquiring and combining multiple SSFP images in an augmented matrix where an acquisition vector in k-space is equal to a Fourier matrix of the trajectory on a known distortion operator for each trajectory in k-space.
    Type: Application
    Filed: July 11, 2005
    Publication date: September 28, 2006
    Inventors: Michael Lustig, John Pauly
  • Publication number: 20060214659
    Abstract: In imaging a first species having a short T2 magnetic resonance parameter in the presence of a second and third species having longer T2 parameters, a method of suppressing signals from the longer T2 species comprises the steps of: a) applying a RF saturation pulse with multiple suppression bands for the second and third species to excite nuclei spins of the longer T2 species with the magnitude of the RF pulse being sufficiently low so as not to excite nuclei spins of the short T2 species, the RF saturation pulse being sufficiently long to rotate the longer T2 species nuclei spins into a transverse plane, and b) dephasing the longer T2 species nuclei spins in the transverse plane. An imaging pulse sequence is then applied to image the short T2 species.
    Type: Application
    Filed: July 12, 2005
    Publication date: September 28, 2006
    Inventors: Peder Larson, John Pauly, Steven Conolly
  • Publication number: 20060109004
    Abstract: Magnetic resonance imaging utilizes view angle tilting to correct for in-plane distortions with each RF excitation pulse being followed by a plurality of signal readouts to reduce image blurring. Each image readout is in the presence of a frequency select gradient (Gx) and a slice select gradient (Gz), and at least the slice select gradient is refocused after each readout of an image signal. Each readout can have a time duration of the main lobe of the RF excitation pulse or the readout can have a higher bandwidth with an increased number of readouts. The combining of multiple readouts diminishes slice profile modulation resulting from Fourier transform.
    Type: Application
    Filed: November 23, 2004
    Publication date: May 25, 2006
    Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Kim Butts, John Pauly
  • Publication number: 20050225323
    Abstract: A method for designing non-linear phase 180° spectral-spatial radio frequency pulses that can be used for spectral editing in magnetic resonance spectroscopic imaging. A novel feature of the pulse is a symmetric sweep developed by the spectral profile from the outside edges of the spectral window towards the middle whereby coupled components are tipped simultaneously and over a short interval. Pulses have been designed for lactate editing at 1.5 T and 3 T. The spectral and spatial spin-echo profiles of the RF pulses can be measured experimentally and altered in an iterative manner. Spectral-spatial radio frequency (SSRF) pulses allow simultaneous selection in both frequency and spatial domains. These pulses are particularly important for clinical and research magnetic resonance spectroscopy (MRS) applications for suppression of large water and lipid resonances.
    Type: Application
    Filed: April 13, 2004
    Publication date: October 13, 2005
    Inventors: Charles Cunningham, John Pauly, Daniel Vigneron
  • Patent number: 5309099
    Abstract: Real-time spatially localized velocity distribution is measured using magnetic resonance techniques by first exciting a region of interest using an RF excitation pulse simultaneously with gradient pulses along two orthogonal axes. A cyclical read-out gradient is then applied along a read-out axis and a magnetic resonance signal is continuously sampled while the read-out gradient is applied. The excitation and read-out is repeated at time intervals to obtain time varying spatially localized velocities within the region of interest.
    Type: Grant
    Filed: August 7, 1992
    Date of Patent: May 3, 1994
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Pablo Irarrazabal, Bob S. Hu, John Pauly
  • Patent number: 4467163
    Abstract: Disclosed is a system for accurately sensing the temperature of articles being heated in a microwave oven. Basic structural elements of the invention are a housing that defines an oven chamber, a door providing access thereto and an energy source for transmitting microwave energy into the chamber. A temperature responsive sensor is positioned within the chamber and is adapted to sense the temperature of articles being heated therein. Enclosing the sensor is an elongated sensor body formed of an electrically conductive material so as to provide a shield for microwave energy and having a length that establishes therfor a detuned antenna condition at the microwave transmission frequency of the source. An electrical control circuit is coupled between the source and the sensor and controls energization of the source in response to temperature levels sensed by the sensor.
    Type: Grant
    Filed: January 19, 1981
    Date of Patent: August 21, 1984
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: John A. Pauly, Richard W. Cenedella
  • Patent number: 4427866
    Abstract: Disclosed is an electrical connection system for a microwave oven including a chamber defining a housing, a source for transmitting microwave energy into the chamber, a turntable rotatably mounted within the chamber and defining stations for receiving articles to be heated and a drive mechanism for producing rotation of the turntable. A control circuit controls energization of the source in response to signal outputs from temperature responsive sensors positioned in the heating stations. The rotary coupling includes a stationary portion mounted on the housing and having stationary contacts connected to the control circuit and a rotary portion mounted on the turntable and having rotary contacts connected to the sensors and slidably engaging the stationary contacts during rotational movement of the turntable.
    Type: Grant
    Filed: January 11, 1982
    Date of Patent: January 24, 1984
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: John A. Pauly, John K. Malinoski
  • Patent number: 4204186
    Abstract: The invention is a temperature probe including an elongated electrically conductive housing having one closed end and one open end. Electrically connected to the inner surface of the closed end is one lead of a thermistor, the second lead of which is connected to the inner conductor of a coaxial cable extending into the open end of the housing. The outer conductor of the cable is electrically connected to the housing near its open end in such a manner as to compress the cable within the housing and induce longitudinal deformation thereof. The compression of the cable within the housing insures that the first thermistor lead is in intimate contact with the closed end of the housing when an electrical connection is made therebetween, preferably by a heliarc welding operation.
    Type: Grant
    Filed: August 16, 1978
    Date of Patent: May 20, 1980
    Assignee: Walter Kidde & Company, Inc.
    Inventors: Michael S. Parisi, John A. Pauly
  • Patent number: 4201968
    Abstract: The invention is a temperature probe assembly including a probe for insertion into food products and comprising a temperature responsive sensor. Secured to the probe is a coaxial cable having electrically isolated inner and outer conductors connected to the temperature responsive sensor and an outer insulative sheath. The insulative sheath is discontinuous so as to create at a plurality of spaced apart locations on the cable insulation gaps in which a length of the outer conductor is exposed. Molded over each of the insulation gaps and bonded intimately to each of the exposed lengths of the outer conductor is an insulative unit. In response to a predetermined relative movement between an insulative unit and the insulative sheath, the attached length of outer conductor is severed to open an electrical circuit.
    Type: Grant
    Filed: August 16, 1978
    Date of Patent: May 6, 1980
    Assignee: Walter Kidde & Co., Inc.
    Inventors: Michael S. Parisi, John A. Pauly