Patents by Inventor John A. Ray
John A. Ray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8673948Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.Type: GrantFiled: August 19, 2011Date of Patent: March 18, 2014Assignee: GlaxoSmithKline, LLCInventors: Philip Stewart Turnbull, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
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Publication number: 20110301203Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.Type: ApplicationFiled: August 19, 2011Publication date: December 8, 2011Applicant: GLAXOSMITHKLINE LLCInventors: Philip Stewart Turnbull, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
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Patent number: 8026262Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.Type: GrantFiled: July 1, 2009Date of Patent: September 27, 2011Assignee: GlaxoSmithKline LLCInventors: Philip Stewart Turnbull, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
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Publication number: 20100240642Abstract: The present invention relates to certain indole derivatives that are modulators of PPAR?, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medicine.Type: ApplicationFiled: August 31, 2007Publication date: September 23, 2010Applicant: SMITHKLINE BEECHAM CORPORATIONInventors: Jeffrey Alan Oplinger, Paul Kenneth Spearing, Millard Hurst Lambert, John A. Ray, Christopher P. Laudeman, Jerzy R. Szewczyk, Pierette Banker
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Publication number: 20090264482Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.Type: ApplicationFiled: July 1, 2009Publication date: October 22, 2009Applicant: SMITHKLINE BEECHAM CORPORATIONInventors: Philip Stewart Turnbull, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
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Patent number: 7572820Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.Type: GrantFiled: September 27, 2007Date of Patent: August 11, 2009Assignee: SmithKline Beecham CorporationInventors: Philip Stewart Turnbull, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
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Patent number: 7402606Abstract: Heterocycle substituted ketoamide derivatives of Formula (I), wherein the substitutes A, D, A and R are defined as in claim in, which are useful as cathepsin K inhibitors are described herein. The described invention also includes methods of making such heterocycle substituted ketoamide derivatives as well as method of using the same in the manufacture of medicaments for the treatment of disorders, including osteoporosis, associated with an imbalance between bone resorption and formation which can ultimately lead to fracture.Type: GrantFiled: April 1, 2003Date of Patent: July 22, 2008Assignee: SmithKline Beecham CorporationInventors: David Gene Barrett, John G. Catalano, David Norman Deaton, Aaron Bayne Miller, John A. Ray, Vicente Samano
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Publication number: 20080139631Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.Type: ApplicationFiled: September 27, 2007Publication date: June 12, 2008Applicant: SmithKline Beecham CorporationInventors: Philip Stewart TURNBULL, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
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Patent number: 5569829Abstract: A method is provided for making fruit (particularly tomatoes) having increased solids content which comprises cultivating fruit-bearing plants in which expression of genes homologous to pTOM36 is at least partially inhibited. For this purpose the fruit may be transformed with DNA constructs comprising a DNA sequence homologous to some or all of the gene encoded by the clone pTOM36. The clone is adapted to generate sense or antisense RNA under control of a plant promoter.Type: GrantFiled: June 9, 1993Date of Patent: October 29, 1996Assignee: Imperial Chemical IndustriesInventors: Colin R. Bird, Jeremy M. Boniwell, Donald Grierson, John A. Ray, Wolfgang W. Schuch
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Patent number: 5484906Abstract: DNA clones, e.g. M13-1, comprising at least part of a gene derived from melon that encodes ethylene-forming enzyme. Such clones may comprise DNA constructs including plant promoters capable of expressing RNA in plant cells. Such constructs may be used to inhibit production of ethylene-forming enzyme in transformed plants, and thereby to produce slower-ripening fruit, particularly melons. The clones may be obtained by PCR using specific oligo-nucleotide primers.Type: GrantFiled: August 2, 1993Date of Patent: January 16, 1996Assignee: Zeneca LimitedInventors: Colin R. Bird, John A. Ray, Wolfgang W. Schuch
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Patent number: 5449764Abstract: DNA clones, e.g. P13-B, comprising at least part of a gene derived from peach that encodes ethylene-forming enzyme. Such clones may comprise DNA constructs including plant promoters capable of expressing RNA in plant cells. Such constructs may be used to inhibit production of ethylene-forming enzyme in transformed plants, and thereby to produce slower-ripening fruit, particularly peaches. The clones may be obtained by PCR using specific oligo-nucleotide primers.Type: GrantFiled: June 17, 1993Date of Patent: September 12, 1995Assignee: Zeneca LimitedInventors: Colin R. Bird, John A. Ray, Wolfgang W. Schuch
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Patent number: 5304490Abstract: DNA constructs useful for modifying the ripening behavior of fruit comprise a transcriptional initiation region operative in plants positioned for transcription of a DNA sequence homologous to some or all of a fruit-ripening gene encoded by either of the clones pTOM136 or pTOM66, so that the construct can generate RNA in plant cells. Also plant cells and plants transformed with such constructs.Type: GrantFiled: August 23, 1991Date of Patent: April 19, 1994Assignee: Imperial Chemical Industries PLCInventors: Colin R. Bird, Ruper G. Fray, Donald Grierson, Grantley W. Lycett, John A. Ray, Wolfgang W. Schuch
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Patent number: 5254800Abstract: DNA constructs comprise a DNA sequence homologous to some or all of the gene encoded by the clone pTOM36. The constructs may further comprise a transcriptional initiation region operative in plants for transcribing this DNA sequence, optionally in the antisense direction to produce mRNA complementary to the pTOM36 gene. Transformed plant cells and plants may be derived from such constructs: fruit from the plants (such as tomatoes) are expected to have modified ripening properties.Type: GrantFiled: October 19, 1990Date of Patent: October 19, 1993Assignee: Imperial Chemical Industries PLCInventors: Colin R. Bird, Donald Grierson, John A. Ray, Wolfgang W. Schuch
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Patent number: H531Abstract: Novel anilide derivatives of the formulaZ--ArwhereinZ is a heterocyclic ring system attached to Ar through a ring nitrogen atom in Z, andAr is a substituted phenyl ring, exhibit good control of broadleaf weeds and safety to important crops at low application rates.Type: GrantFiled: June 3, 1986Date of Patent: October 4, 1988Inventors: John A. Ray, Thomas N. Wheeler
