Abstract: A non-linear conversion capability within an on-chip, per-column analog-to-digital converter (ADC) is provided to expand a compressed analog signal such that the resulting digital output that has a predetermined (linear or non-linear) mapping with respect to input brightness level of an incoming light signal to a row of pixels. The predetermined mapping may also be provided by a non-linear amplifier coupled to a linear or non-linear ADC and a resulting compressed non-linear digital representation at the output of the ADC is substantially linearized by an on-chip or an off-chip look-up table (LUT).

Abstract: The disclosure generally relates to a method of producing a handleable wafer of medicament powder (for example, aspirin powder) by utilizing a restraining envelope of fine water-soluble fibers, which are, upon use, quickly dissolved by bodily fluids. Such wafer would quickly provide sublingual or buccal cavity medications without significant excipients. Additional applications for such a wafer is in the prompt provision of a variety of medicaments to selected moist areas, such as, surgery or trauma sites, such as, a wound dressing.

Abstract: The present invention relates to an adjustable star wheel and guide rail assembly for use with containers being processed on an automated handling line between machines such as rotary packaging machines. Star wheels derive their name from their general shape. The star wheels of this invention have fingers that support containers, such that they convey the containers as the star wheel rotates. Conveniently, the fingers of the present invention may be set in any position within their range of movement. In addition, a supporting guide rail may be adjusted, for example by rotation on cams. Thus, the fingers and the guide rail may be set to convey containers of varying sizes while keeping the container's centers travelling along the centerline of the conveyor.

Abstract: A method and apparatus for equalizing gain in an array of electron multiplication (EM) pixels is disclosed, each pixel having one or more impact ionization gain stages with implants to achieve charge transfer directionality and comprising a phase 1 clocked gate, an EM clocked gate, and two DC gates formed between the phase 1 clocked gate and the EM clocked gate, comprising the steps of (a) applying initial voltages to each of the DC gates and the EM clocked gates of at least two pixels of a plurality of pixels; (b) clocking phase 1 clock gates and an EM clock gates associated with the at least two pixels of the plurality of pixels a predetermined number of times to achieve an average pixel intensity value after impact ionization gain; and (c) selectively adjusting the difference in voltage between the DC gate and corresponding EM clocked gate of the at least two pixels of the plurality of pixels until the difference between the resulting pixel intensity values and the average pixel intensity value needed to p

Abstract: A surface treatment material useful in making coatings to be applied to fomitic surfaces to inhibit the proliferation of microorganisms, especially bacteria, comprises a photocatalytic component consisting of a metal oxide catalyst together with a metal dopant acting as an upconversion luminescence agent, for example based upon ErCl3, TiO2, Er(NO3)3/TiO2, NdCl3/TiO2, Nd(NO3)3/TiO2, GdCl3/TiO2, Gd(NO3)/TiO2, and optionally including other metals, especially a transition metal such as silver, provides antimicrobial activity in the dark, and enhanced antibacterial activity when exposed to wavelengths in the range of 350 to 790 nm, and thus finds utility in the healthcare, leisure and food industries.

Abstract: One can identify and quantify one or more glycosylation markers of cancer by utilizing quantitative HPLC analysis of glycans which have been released from unpurified glycoproteins. The unpurified glycoproteins can be total glycoproteins or a selection of the total glycoproteins. The identified glycosylation marker can be a native glycan or a digestion product which has been segregated and amplified by exoglycosidase digestions. One can utilize the identified glycosylation marker, for example, for diagnosing and/or monitoring cancer in a subject. One can also use the glycosylation marker to identify glycoprotein biomarkers that carry the glycosylation marker. Such biomarkers can also be used for monitoring and/or diagnosing cancer. The biomarker may also be a subset of glycoforms of a glycoprotein that are separated in trains of spots on 2D gel.

Abstract: This disclosure describes embodiments of novel line dispensing devices and methods for dispensing and retracting a line of a line dispensing device.

Abstract: A first method comprises: dissolving a polymer in a terpene, terpenoid, or aromatic solvent to form a polymer solution; dissolving a salt in a polar organic solvent to form a salt solution; and mixing the salt solution and the polymer solution to form a mixture. The salt and the polar organic solvent do not cause substantial precipitation of the polymer upon mixing with the polymer solution. A resulting terpene, terpenoid, or aromatic solvent phase of the mixture is suitable for forming fibers by electric-field-driven spinning from one or more spinning tips onto a target substrate. A composition comprises the terpene, terpenoid, or aromatic solvent phase of the mixture resulting from the method. A second method comprises forming fibers by electric-field-driven spinning of the first composition from one or more spinning tips onto a target substrate. A second composition comprises the fibers formed by the second method.

Abstract: A pixel for an imager is disclosed that includes at least one electron multiplication (EM) gain stage configured in a loop and electrically coupled to a charge collection region and a charge readout region, the charge collection region being configured to generate a charge packet, the EM gain stage being configured to amplify the charge packet by impact ionization and to circulate the charge packet a predetermined number of times in one direction around the loop, the charge readout region being configured to receive the amplified charge packet and convert the amplified charge to a measurable signal. The at least one EM gain stage, the charge collection region, and the charge readout region can be formed monolithically in an integrated circuit. The pixel can be manufactured using a CMOS process. The pixel can further include a second EM gain stage formed in the integrated circuit to increase the amount of amplification around the loop.

Abstract: An automated handling line guide rail assembly. The automated handling line guide rail assembly comprises a guide rail that defines the perimeter of a path of a container when conveyed along part of an automated handling line. The path and hence the perimeter are arcuate about a center and positioned at a radius from the center. The guide rail is movable radially to define the perimeter at a plurality of different radii from substantially the same center and the guide rail comprises at least three segments. The first segment is driveable in a substantially radial direction; the second segment is connected to the first segment by a link and the third segment is connected to the second segment by a link such that the second and third segments follow movement of the first segment.

Abstract: A carbon dioxide absorbent suitable for use in anesthesiology during low flow or closed circuit made of from 70 to 90% hydrated lime, from 0.1 to 17% of lithium hydroxide or its precursor, or a combination thereof, and from 5 to 25% water, wherein the absorbent provides low Compound A by-product, and high absorbency.

Abstract: An electrohydrodynamic spraying or spinning deposition system, which includes a common source of pressurized liquid within a manifold, and an array of 2 or more spraying tips, each tip being fed from the common source of pressurized liquid to create a liquid flow path. An individual flow impedance device is disposed within each tip's individual liquid flow path from the pressurized liquid source into each spraying tip. The individual flow impedance devices are disposed within a replaceable sheet, which can be easily cleaned or changed to accommodate the instance liquid viscosity and composition. A high voltage source is applied to create a high voltage potential applied between the tip array and a deposition surface.

Abstract: Disclosed is the presentation of text data on a high-resolution display screen using an image, which includes nonlinear (3D) surface undulation and viewing perspective. This presentation results in variations of character size, rotation, and aspect across the screen. Additionally, positional cues, and coloration gradations may be added. As will be shown, all of this assists human readability and reduces fatigue.

Abstract: A process for preparing a particle comprising a biological molecule typically a DNA plasmid, and a carrier polymer, typically poly-lactic acid (PLA), in which an organic solvent solution of the biological molecule and the carrier polymer in an organic solvent medium, nearly saturated with the biological molecule, is prepared, then this solution is contacted with an antisolvent substance, typically supercritical carbon dioxide to separate a particle comprising the biological molecule and the carrier polymer. High loadings of the biological molecule in the particle can be achieved.

Abstract: An electrohydrodynamic spraying or spinning deposition system, which includes a common source of pressurized liquid within a manifold, and an array of 2 or more spraying tips, each tip being fed from the common source of pressurized liquid to create a liquid flow path. An individual flow impedance device is disposed within each tip's individual liquid flow path from the pressurized liquid source into each spraying tip. The individual flow impedance devices are disposed within a replaceable sheet, which can be easily cleaned or changed to accommodate the instance liquid viscosity and composition. A high voltage source is applied to create a high voltage potential applied between the tip array and a deposition surface.

Abstract: A method and apparatus for equalizing gain in an array of electron multiplication (EM) pixels is disclosed, each pixel having one or more impact ionization gain stages with implants to achieve charge transfer directionality and comprising a phase 1 clocked gate, an EM clocked gate, and two DC gates formed between the phase 1 clocked gate and the EM clocked gate, comprising the steps of (a) applying initial voltages to each of the DC gates and the EM clocked gates of at least two pixels of a plurality of pixels; (b) clocking phase 1 clock gates and an EM clock gates associated with the at least two pixels of the plurality of pixels a predetermined number of times to achieve an average pixel intensity value after impact ionization gain; and (c) selectively adjusting the difference in voltage between the DC gate and corresponding EM clocked gate of the at least two pixels of the plurality of pixels until the difference between the resulting pixel intensity values and the average pixel intensity value needed to p

Abstract: The present invention regards methods and formulations for the treatment of diabetes and the prevention of autoimmune diabetes. The invention includes the administration of human recombinant GAD65 protein in a pharmaceutically acceptable adjuvant.

Abstract: The present invention is a device for delivering a low frequency magnetic field pulse (Cnp) to affect the physiological and/or neurological conditions of an animal or human. In particular, distinct Cnps are designed to have anti-depression, analgesic, or anti-anxiety effects. These Cnps may be applied in combination in a sequence.