Patents by Inventor John A. Ryals

John A. Ryals has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of inducing gene transcription in a plant
    Patent number: 5789214
    Abstract: The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chimeric constructions, and transgenic plants and plant tissues containing these chimeric constructions. In one aspect, the chemically regulatable DNA sequences of the invention are derived from the 5' region of genes encoding pathogenisis-related (PR) proteins. The present invention also provides anti-pathogenic sequences derived from novel cDNAs coding for PR proteins which can be genetically engineered and transformed into plants to confer enhanced resistance to disease.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: August 4, 1998
    Assignee: Novartis Finance Corporation
    Inventors: John A. Ryals, Leslie B. Friedrich, Scott J. Uknes, Eric R. Ward
  • Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
    Patent number: 5777200
    Abstract: The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chimeric constructions, and transgenic plants and plant tissues containing these chimeric constructions. In one aspect, the chemically regulatable DNA sequences of the invention are derived from the 5' region of genes encoding pathogenisis-related (PR) proteins. The present invention also provides anti-pathogenic sequences derived from novel cDNAs coding for PR proteins which can be genetically engineered and transformed into plants to confer enhanced resistance to disease.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: July 7, 1998
    Assignee: Novartis Finance Corporation
    Inventors: John A. Ryals, Danny C. Alexander, Robert M. Goodman, Jeffrey R. Stinson
  • DNA sequences encoding SAR8.2 proteins and uses thereof
    Patent number: 5767369
    Abstract: The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chimeric constructions, and transgenic plants and plant tissues containing these chimeric constructions. In one aspect, the chemically regulatable DNA sequences of the invention are derived from the 5' region of genes encoding pathogenisis-related (PR) proteins. The present invention also provides anti-pathogenic sequences derived from novel cDNAs coding for PR proteins which can be genetically engineered and transformed into plants to confer enhanced resistance to disease.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: June 16, 1998
    Assignee: Novartis Finance Corporation
    Inventors: John A. Ryals, Danny C. Alexander, Robert M. Goodman, Jeffrey R. Stinson
  • Genes for the biosynthesis of soraphen
    Patent number: 5716849
    Abstract: The present invention is directed to the production of a polyketide antibiotic such as soraphen in a host via recombinant expression of the polypeptides needed to biologically synthesize the polyketide antibiotic. Polyketide synthase (PKS) genes encoding polypeptides necessary to synthesize soraphen are provided, along with methods for identifying and isolating the PKS genes needed to recombinantly biosynthesize any desired polyketide antibiotic. The cloned PKS genes may be transformed and expressed in a desired host organisms to produce soraphen for a variety of purposes, including protecting the host from a pathogen, developing the host as a biocontrol agent, and producing large, uniform amounts of soraphen.
    Type: Grant
    Filed: December 14, 1996
    Date of Patent: February 10, 1998
    Assignee: Novartis Finance Corporation
    Inventors: James M. Ligon, Thomas Schupp, James J. Beck, Dwight S. Hill, Snezana Neff, John A. Ryals
  • Chemically inducible promoter of a plant PR-1 gene
    Patent number: 5689044
    Abstract: The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chimeric constructions, and transgenic plants and plant tissues containing these chimeric constructions. In one aspect, the chemically regulatable DNA sequences of the invention are derived from the 5' region of genes encoding pathogenisis-related (PR) proteins. The present invention also provides anti-pathogenic sequences derived from novel cDNAs coding for PR proteins which can be genetically engineered and transformed into plants to confer enhanced resistance to disease.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: November 18, 1997
    Assignee: Novartis Corporation
    Inventors: John A. Ryals, Leslie B. Friedrich, Scott J. Uknes, Eric R. Ward
  • Chemically inducible promoter of a cucumber chitinase/lysozyme gene
    Patent number: 5654414
    Abstract: The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chimeric constructions, and transgenic plants and plant tissues containing these chimeric constructions. In one aspect, the chemically regulatable DNA sequences of the invention are derived from the 5' region of genes encoding pathogenisis-related (PR) proteins. The present invention also provides anti-pathogenic sequences derived from novel cDNAs coding for PR proteins which can be genetically engineered and transformed into plants to confer enhanced resistance to disease.
    Type: Grant
    Filed: May 19, 1995
    Date of Patent: August 5, 1997
    Assignee: Novartis Finance Corporation
    Inventors: John A. Ryals, James J. Beck, Leslie B. Friedrich
  • Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
    Patent number: 5650505
    Abstract: The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chimeric constructions, and transgenic plants and plant tissues containing these chimeric constructions. In one aspect, the chemically regulatable DNA sequences of the invention are derived from the 5' region of genes encoding pathogenisis-related (PR) proteins. The present invention also provides anti-pathogenic sequences derived from novel cDNAs coding for PR proteins which can be genetically engineered and transformed into plants to confer enhanced resistance to disease.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: July 22, 1997
    Assignee: Novartis Corporation
    Inventors: John A. Ryals, Danny C. Alexander, James J. Beck, John H. Duesing, Robert M. Goodman, Leslie B. Friedrich, Christian Harms, Frederich Meins, Jr., Alice Montoya, deceased, Mary B. Moyer, Jean-Marc Neuhaus, George B. Payne, Christoph Sperisen, Jeffrey R. Stinson, Scott J. Uknes, Eric R. Ward, Shericca C. Williams
  • Anti-pathogenically effective compositions comprising lytic peptides and hydrolytic enzymes
    Patent number: 5631007
    Abstract: Anti-pathogenically effective compositions are provided containing a combination of hydrolytic enzymes and lytic peptides as the active agent. Methods of controlling the growth of pathogens using the anti-pathogenically effective compositions are provided. Transgenic plants that contain genes that are able to express lytic peptides and hydrolytic enzymes are also provided.
    Type: Grant
    Filed: June 8, 1994
    Date of Patent: May 20, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: John A. Ryals, Philippe B. Gay, Patricia A. Ahl-Goy
  • Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
    Patent number: 5614395
    Abstract: The present invention provides chemically regulatable DNA sequences capable of regulating transcription of an associated DNA sequence in plants or plant tissues, chimeric constructions containing such sequences, vectors containing such sequences and chimeric constructions, and transgenic plants and plant tissues containing these chimeric constructions. In one aspect, the chemically regulatable DNA sequences of the invention are derived from the 5' region of genes encoding pathogenisis-related (PR) proteins. The present invention also provides anti-pathogenic sequences derived from novel cDNAs coding for PR proteins which can be genetically engineered and transformed into plants to confer enhanced resistance to disease.
    Type: Grant
    Filed: January 13, 1994
    Date of Patent: March 25, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: John A. Ryals, Danny C. Alexander, James J. Beck, John H. Duesing, Robert M. Goodman, Leslie B. Friedrich, Christian Harms, Frederich Meins, Jr., Alice Montoya, deceased, Mary B. Moyer, Jean-Marc Neuhaus, George B. Payne, Christoph Sperisen, Jeffrey R. Stinson, Scott J. Uknes, Eric R. Ward, Shericca C. Williams
  • Anti-pathogenically effective compositions comprising lytic peptides and hydrolytic enzymes
    Patent number: 5348743
    Abstract: Anti-pathogenically effective compositions are provided containing a combination of hydrolytic enzymes and lytic peptides as the active agent. Methods of controlling the growth of pathogens using the anti-pathogenically effective compositions are provided. Transgenic plants that contain genes that are able to express lytic peptides and hydrolytic enzymes are also provided.
    Type: Grant
    Filed: June 25, 1993
    Date of Patent: September 20, 1994
    Assignee: Ciba-Geigy Corporation
    Inventors: John A. Ryals, Philippe B. Gay, Patricia A. Ahl-Goy
  • Isolated DNA Encoding plant histidinol dehydrogenase
    Patent number: 5290926
    Abstract: The present invention comprises cDNA coding for histidinol dehydrogenase from plants, the final step in histidine biosynthesis. The invention also comprises a novel method of purifying histidinol dehydrogenase from plants to essential honogeneity, the purified histidinol dehydrogenase, an assay for identifying inhibitors of histidinol dehydrogenase, an assay to identify mutants of histidinol dehydrogenase that are not inhibited by inhibitors of wild-type histidinol dehydrogenase, the inhibitors so identified as well as herbicide compositions containing them, the non-inhibited mutants of histidinol dehydrogenase, transgenic crop plants containing the non-inhibited mutants of histidinol dehydrogenase, and methods of treating weeds utilizing the application of histidinol dehydrogenase inhibitors to the transgenic crops containing the non-inhibited mutants of histidinol dehydrogenase.
    Type: Grant
    Filed: September 14, 1990
    Date of Patent: March 1, 1994
    Assignee: Ciba-Geigy Corporation
    Inventors: Alfred Scheidegger, Eric R. Ward, John A. Ryals, Atsuko Nagai-Hayashi