Abstract: A method for calculating a subject's state or condition comprises integrating data that are captured from multiple sources, storing the integrated data in a first database, calculating time intervals in which to collect an optimal amount of data to predict the subject state, developing a predictive model using a recorded diary or electronic data capture information, testing the model against a portion of the captured data, and applying the predictive model to new data from other sources. The predictive model may determine a subject state that may be a digital bio-marker for a disease condition. A system for predicting subject state is also disclosed.

Abstract: A method for calculating a subject's state or condition comprises integrating data that are captured from multiple sources, storing the integrated data in a first database, calculating time intervals in which to collect an optimal amount of data to predict the subject state, developing a predictive model using a recorded diary or electronic data capture information, testing the model against a portion of the captured data, and applying the predictive model to new data from other sources. The predictive model may determine a subject state that may be a digital bio-marker for a disease condition. A system for predicting subject state is also disclosed.

Abstract: A medical device assembly including a catheter having a proximal end, a distal end, and a lumen therethrough. A medical device is disposed about a distal portion of the catheter. A removable loading tool and protector is disposed about the catheter and the medical device, and includes a body having a generally tubular configuration and having a proximal end, a distal end, an intermediate region disposed between the proximal end and the distal end, and a lumen disposed therethrough; and a proximal region having a length and extending from the proximal end of the body, the proximal region having at least one slit positioned adjacent to the proximal end of the body. The proximal region has a first inner diameter and the intermediate region has a second inner diameter, the first inner diameter of the proximal region being greater than the second inner diameter of the intermediate region.

Abstract: A scrubs returns cabinet for a hospital allows workers to return surgical garment tops and bottoms. A cabinet housing has a loading door leading to a return port through which the customer places the soiled scrub suit after entering customer identification information. The scrubs fall into a collection area and are dispersed by a diverter into the collection area. Additionally, a compacting paddle compacts the accumulating scrubs to utilize more of the collection area and accommodate more dirty scrubs before the collection area needs to be emptied. The scrubs are compressed by the compactor after being dispersed by the diverter.

Abstract: An apparatus for predicting an outcome of a patient includes a processor, and a memory storing computer executable instructions, which when executed by the processor cause the processor to perform operations comprising obtaining patient kinematic data of the patient; deriving one or more patient kinematic features from the patient kinematic data; and determining the outcome based on the one or more patient kinematic features and at least one additional data element of the patient using an outcome model trained on a training set of kinematic features of the same type as the patient kinematic features and the at least one additional data element.

Abstract: An apparatus for performing a remote test of range of motion of a person operating a user device includes a transceiver, a processor, and a display. The transceiver is configured to transmit a link to the user device and to receive motion data from the user device. The processor is configured to calculate in real time, based on the motion data, the position of the user device to enable real-time display to a test provider of the performance of the test and to determine in real time the quality of the test. The display is configured to show in real time a continuous indication of the performance of the test and quality results of the test. A method for performing a remote test of range of motion of a person operating a user device is also described and claimed.

Abstract: A dispenser for scrubs or other items is modular and can be configured with a desired number of cells for storing scrubs and dispensing them accordingly. The dispenser includes a main or primary bank of cells with each cell housing an inventory of multiple scrubs for dispensing. The main bank of cells may operate in a standalone manner to dispense scrubs, or additional banks can be added to the main bank for increased inventory capacity. The scrubs are stored in a vertical stack in each cell with the uppermost scrub in the cell being the next scrub in that cell to be dispensed. One or more pickers each translate along a gantry to be selectively positioned above one of the cells for picking to pull the uppermost scrub in the cell and elevate it out of the cell. Multiple pickers may operate simultaneously to pick and dispense multiple scrubs at the same time. Each cell includes a platform supporting the vertical stack of scrubs.

Abstract: A scrubs returns cabinet for a hospital allows workers to return surgical garment tops and bottoms. A cabinet housing has a loading door leading to a return port through which the customer places the soiled scrub suit after entering customer identification information. The scrubs fall into a collection area and are dispersed by a diverter into the collection area. Additionally, a compacting paddle compacts the accumulating scrubs to utilize more of the collection area and accommodate more dirty scrubs before the collection area needs to be emptied. The scrubs are compressed by the compactor after being dispersed by the diverter.

Abstract: An electronic device for compressing sampled data comprises a memory element and a processing element. The memory element is configured to store sampled data points and sampled times. The processing element is in electronic communication with the memory element and is configured to receive a plurality of sampled data points, a slope for each sampled data point in succession, the slope being a value of a change between the sampled data point and its successive sampled data point, and store the sampled data point in the memory element when the slope changes in value from a previous sampled data point.

Abstract: An electronic device for compressing sampled data comprises a memory element and a processing element. The memory element is configured to store sampled data points and sampled times. The processing element is in electronic communication with the memory element and is configured to receive a plurality of sampled data points, a slope for each sampled data point in succession, the slope being a value of a change between the sampled data point and its successive sampled data point, and store the sampled data point in the memory element when the slope changes in value from a previous sampled data point.

Abstract: A method is provided for determining at least one candidate reactant. One embodiment of this method includes the following steps: forming by a computer processor a graph of known reactants and known products, the graph comprising links between the known reactants and their known products, receiving by a computer processor the target compound, determining by a computer processor whether the graph includes the target compound and adding the target compound to the graph if the target compound was not previously included, forming by a computer processor a matrix representing at least a portion of the known reactants, a portion of the known products and the target compound, providing a matrix value of the graph by a computer processor for one or more candidate reactants and determining by a computer processor at least one link in the graph between the target compound and the candidate reactant based on matrix values.

Abstract: Techniques for efficient retrosynthesis analysis are provided. A computer-implemented method for determining whether a target compound can be synthesized using known pathways for similar compounds includes receiving, by a processor, target compound data including a target compound. The method further includes obtaining, by the processor, a similar compound to the target compound, along with a reaction rule for synthesizing the similar compound. The method further includes applying, by the processor, the reaction rule to the target compound to generate a set of precursors. The method further includes generating, by the processor, a notification based on the set of precursors.

Abstract: Embodiments include an optical system comprising a plurality of powered optical elements, arranged within a same optical path, configured to simultaneously pass and focus therethrough mid-wave infrared (MWIR) and long-wave infrared (LWIR) spectral bands to a focal plane array (FPA) and provide simultaneous correction of monochromatic and chromatic aberrations over the MWIR and LWIR spectral bands with a low f-theta distortion. The plurality of powered optical elements comprises a first set of powered lenses having a passive athermalized response over fluctuating temperatures in a variable temperature environment; and a second set of powered lenses to operate in a constant cryogenically cooled environment. A method and a situational-awareness device are also disclosed.

Abstract: An acoustic detector provides a planar arrangement of microphones. A windshield is arranged over the microphones, with a view to reducing the impact of environmental effects. A void is therefore defined over the microphones, and the interior surface of the windshield, which defines the void, is shaped suitably to reduce the potential for acoustic waves propagating within the void to reflect back onto the microphones.

Abstract: A delivery system for percutaneously deploying a stented prosthetic heart valve. The system includes a delivery capsule and a recapture assembly. The capsule is configured to compressively retain the prosthesis. The recapture assembly includes a frame and sleeve attached to the frame. The recapture assembly is transitionable from a compressed arrangement to an expanded arrangement with a distally increasing diameter.

Abstract: An apparatus for performing a remote test of range of motion of a person operating a user device includes a transceiver, a processor, and a display. The transceiver is configured to transmit a link to the user device and to receive motion data from the user device. The processor is configured to calculate in real time, based on the motion data, the position of the user device to enable real-time display to a test provider of the performance of the test and to determine in real time the quality of the test. The display is configured to show in real time a continuous indication of the performance of the test and quality results of the test. A method for performing a remote test of range of motion of a person operating a user device is also described and claimed.

Abstract: Techniques for efficient retrosynthesis analysis are provided. A computer-implemented method for determining whether a target compound can be synthesized using known pathways for similar compounds includes receiving, by a processor, target compound data including a target compound. The method further includes obtaining, by the processor, a similar compound to the target compound, along with a reaction rule for synthesizing the similar compound. The method further includes applying, by the processor, the reaction rule to the target compound to generate a set of precursors. The method further includes generating, by the processor, a notification based on the set of precursors.

Abstract: A method is provided for determining at least one candidate reactant. One embodiment of this method includes the following steps: forming by a computer processor a graph of known reactants and known products, the graph comprising links between the known reactants and their known products, receiving by a computer processor the target compound, determining by a computer processor whether the graph includes the target compound and adding the target compound to the graph if the target compound was not previously included, forming by a computer processor a matrix representing at least a portion of the known reactants, a portion of the known products and the target compound, providing a matrix value of the graph by a computer processor for one or more candidate reactants and determining by a computer processor at least one link in the graph between the target compound and the candidate reactant based on matrix values.

Abstract: A system for determining relative operational performance in a clinical trial may include a processor, a data comparator and visualizer, and a graphical user interface. The processor filters received clinical data into multiple metric criteria to generate multiple metric data sets and filters each metric data set into a respective industry data set and a respective candidate data set. The processor then calculates statistical measures for each industry data set and candidate data set and transforms each industry data set and candidate data set based on each data set's respective statistical measures. The data comparator and visualizer compares each transformed candidate data set to the transformed industry data set for the respective metric criterion to determine a candidate percentile for each metric criterion. The graphical user interface displays the candidate percentiles for the metric criteria. A method for determining relative operational performance in a clinical trial is also described.