Abstract: A self-calibration technique which provides detector responsivity normalization for a charge-coupled device, hereinafter referred to as CCD, area imager. The CCD area imager is designed such that the detectors can be electrically decoupled from CCD multiplex register inputs. Calibration reference and gain normalization are provided by a pulsed light source and an analog divider circuit. This technique is applicable to both CCD visible imagers which are fabricated on an intrinsic semiconductor substrate and CCD infrared imagers which can be fabricated on an extrinsic or intrinsic substrate. The technique is applied to a visible imager for illustration of its self-calibration capability.