Patents by Inventor John A. Shepherd

John A. Shepherd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250221680
    Abstract: Systems and methods for determining body composition by combining dual-energy x-ray (DXA) technology with three-dimensional (3D) optical technology and/or bioimpedance technology. A multi-modality scanning system may include a dual-energy x-ray source and an x-ray detector mounted to opposing sides a c-arm and configured to scan a patient on a optically translucent table. The system may also include one or more 3D optical imaging devices to capture 3D optical images of the patient substantially concurrently with the emission of the dual energy x-rays. A bioimpedance machine may also be included in the multi-modality scanning system. Data based on the dual-energy x-rays may be combined with the data from the 3D optical images and/or the bioimpedance data to generate values of at least three compartments selected from: bone, fat tissue, lean tissue, dehydrated lean tissue, and water.
    Type: Application
    Filed: January 6, 2025
    Publication date: July 10, 2025
    Applicants: Hologic, Inc., The Regents of the University of California
    Inventors: KEVIN E. WILSON, JOHN A. SHEPHERD, BENNETT K. NG, MARK GUETERSLOH, CHAO HUANG, THOMAS L. KELLY, WEI WANG, HOWARD WEISS
  • Patent number: 12226250
    Abstract: Systems and methods for determining body composition by combining dual-energy x-ray (DXA) technology with three-dimensional (3D) optical technology and/or bioimpedance technology. A multi-modality scanning system may include a dual-energy x-ray source and an x-ray detector mounted to opposing sides a c-arm and configured to scan a patient on a optically translucent table. The system may also include one or more 3D optical imaging devices to capture 3D optical images of the patient substantially concurrently with the emission of the dual energy x-rays. A bioimpedance machine may also be included in the multi-modality scanning system. Data based on the dual-energy x-rays may be combined with the data from the 3D optical images and/or the bioimpedance data to generate values of at least three compartments selected from: bone, fat tissue, lean tissue, dehydrated lean tissue, and water.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: February 18, 2025
    Assignees: Hologic, Inc., The Regents of the University of California
    Inventors: Kevin E. Wilson, John A. Shepherd, Bennett K. Ng, Mark Guetersloh, Chao Huang, Thomas L. Kelly, Wei Wang, Howard Weiss
  • Publication number: 20250029241
    Abstract: In some examples, anthropometric parameters of a subject are ascertained from radiographic image data. Radiograph image data is transformed to a representation of a lower dimensionality than the dimensionality of the image data by an machine learning processor. The representation of the radio graph image data is mapped to anthropometric parameters, directly or first to an intermediate three-dimensional optical image of the subject, and then from the intermediate three-dimensional optical image to anthropometric parameters.
    Type: Application
    Filed: November 21, 2022
    Publication date: January 23, 2025
    Applicants: Hologic, Inc., University of Hawaii
    Inventors: John A. SHEPHERD, Lambert Thomas Lam King LEONG, Thomas L. KELLY
  • Publication number: 20250017484
    Abstract: In some embodiments, a bioimpedance measurement apparatus includes a set of electrodes configured to be placed on respective skin portions of a subject; a temperature sensor probe configured to be placed on a respective skin portion of the subject; a moisture sensor probe configured to be placed on a respective skin portion of the subject; and an electronic module configured to determine an impedance between at least two of the plurality of electrodes, receive from the temperature probe a temperature signal and determine from the temperature signal a temperature of the skin portion the temperature sensor probe is placed on, receive from the moisture sensor probe a moisture signal and determine a moisture level of the skin portion the moisture sensor probe is placed on, and determine a bioimpedance of the subject based at least in part on the determined impedance, temperature, and moisture level.
    Type: Application
    Filed: November 21, 2022
    Publication date: January 16, 2025
    Applicants: Hologic, Inc., University of Hawaii
    Inventors: Thomas L. KELLY, John A. SHEPHERD
  • Publication number: 20200029927
    Abstract: Systems and methods for determining body composition by combining dual-energy x-ray (DXA) technology with three-dimensional (3D) optical technology and/or bioimpedance technology. A multi-modality scanning system may include a dual-energy x-ray source and an x-ray detector mounted to opposing sides a c-arm and configured to scan a patient on a optically translucent table. The system may also include one or more 3D optical imaging devices to capture 3D optical images of the patient substantially concurrently with the emission of the dual energy x-rays. A bioimpedance machine may also be included in the multi-modality scanning system. Data based on the dual-energy x-rays may be combined with the data from the 3D optical images and/or the bioimpedance data to generate values of at least three compartments selected from: bone, fat tissue, lean tissue, dehydrated lean tissue, and water.
    Type: Application
    Filed: March 22, 2018
    Publication date: January 30, 2020
    Inventors: Kevin E. WILSON, John A. SHEPHERD, Bennett K. NG, Mark GUETERSLOH, Chao HUANG, Thomas L. KELLY, Wei WANG, Howard WEISS
  • Patent number: 7873198
    Abstract: The present invention provides an apparatus and methods for measuring proportions of body materials in body parts. The apparatus includes a device for retaining the body part, at least one reference material with at least two thicknesses positioned adjacent to the device, and at least three radiopaque markers positioned on the reference material(s). The reference material(s) each have an attenuation characteristic that is selected in correspondence to the body materials in the body part. The apparatus further includes a radiation device to simultaneously irradiate the body part, the reference material(s) and the radiopaque markers as well as a detector to detect attenuated beams of radiation and a pattern projected from the irradiated radiopaque markers. A calculation device determines the thickness of the body part based on this projected pattern and compares the attenuation values of the body part and the reference material(s) at the determined thickness.
    Type: Grant
    Filed: June 15, 2006
    Date of Patent: January 18, 2011
    Assignees: Sutter West Bay Hospitals, The Regents of the University of California
    Inventors: John A. Shepherd, Serghei Malkov, Steven R. Cummings
  • Publication number: 20090076382
    Abstract: The present invention provides an apparatus and methods for measuring proportions of body materials in body parts. The apparatus includes a device for retaining the body part, at least one reference material with at least two thicknesses positioned adjacent to the device, and at least three radiopaque markers positioned on the reference material(s). The reference material(s) each have an attenuation characteristic that is selected in correspondence to the body materials in the body part. The apparatus further includes a radiation device to simultaneously irradiate the body part, the reference material(s) and the radiopaque markers as well as a detector to detect attenuated beams of radiation and a pattern projected from the irradiated radiopaque markers. A calculation device determines the thickness of the body part based on this projected pattern and compares the attenuation values of the body part and the reference material(s) at the determined thickness.
    Type: Application
    Filed: June 15, 2006
    Publication date: March 19, 2009
    Inventors: John A. Shepherd, Serghei Malkov, Steven R. Cummings
  • Patent number: 6654445
    Abstract: The present invention provides a radiation device that includes a device for retaining therein the body part in a uniform position. In addition, at least two reference materials that have attenuation characteristics are used and retained in the retaining device. The reference materials are being positioned for the comparative determination during a simultaneous irradiation of the body part and the reference materials. The attenuation characteristics of the reference materials are selected in correspondence to the attenuation characteristics of the body materials in the body part. A radiation device for simultaneously irradiating the body part and the reference materials is used to create attenuated beams. A detector is used to detect the attenuated beams as attenuated values. A calculating device is included for calculating the proportion of the body materials that define a particular body part of interest based on the attenuated values of the materials and the body part.
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: November 25, 2003
    Assignee: Regents of the University of California
    Inventors: John A. Shepherd, Steven R. Cummings, Karla Kerlikowske
  • Publication number: 20030142780
    Abstract: The present invention provides a radiation device that includes a device for retaining therein the body part in a uniform position. In addition, at least two reference materials that have attenuation characteristics are used and retained in the retaining device. The reference materials are being positioned for the comparative determination during a simultaneous irradiation of the body part and the reference materials. The attenuation characteristics of the reference materials are selected in correspondence to the attenuation characteristics of the body materials in the body part. A radiation device for simultaneously irradiating the body part and the reference materials is used to create attenuated beams. A detector is used to detect the attenuated beams as attenuated values. A calculating device is included for calculating the proportion of the body materials that define a particular body part of interest based on the attenuated values of the materials and the body part.
    Type: Application
    Filed: November 22, 2002
    Publication date: July 31, 2003
    Inventors: John A. Shepherd, Steven R. Cummings, Karla Kerlikowske
  • Patent number: 6516045
    Abstract: The present invention provides a radiation device that includes a device for retaining therein the body part in a uniform position. In addition, at least two reference materials that have attenuation characteristics are used and retained in the retaining device. The reference materials are being positioned for the comparative determination during a simultaneous irradiation of the body part and the reference materials. The attenuation characteristics of the reference materials are selected in correspondence to the attenuation characteristics of the body materials in the body part. A radiation device for simultaneously irradiating the body part and the reference materials is used to create attenuated beams. A detector is used to detect the attenuated beams as attenuated values. A calculating device is included for calculating the proportion of the body materials that define a particular body part of interest based on the attenuated values of the materials and the body part.
    Type: Grant
    Filed: May 4, 2001
    Date of Patent: February 4, 2003
    Assignee: The Regents of the University of California
    Inventors: John A. Shepherd, Steven R. Cummings, Karla Kerlikowske
  • Publication number: 20020181651
    Abstract: The present invention provides a radiation device that includes a device for retaining therein the body part in a uniform position. In addition, at least two reference materials that have attenuation characteristics are used and retained in the retaining device. The reference materials are being positioned for the comparative determination during a simultaneous irradiation of the body part and the reference materials. The attenuation characteristics of the reference materials are selected in correspondence to the attenuation characteristics of the body materials in the body part. A radiation device for simultaneously irradiating the body part and the reference materials is used to create attenuated beams. A detector is used to detect the attenuated beams as attenuated values. A calculating device is included for calculating the proportion of the body materials that define a particular body part of interest based on the attenuated values of the materials and the body part.
    Type: Application
    Filed: May 4, 2001
    Publication date: December 5, 2002
    Inventors: John A. Shepherd, Steven R. Cummings, Karla Kerlikowske
  • Patent number: 6282258
    Abstract: A method of measuring bone mineral density (BMD) of a selected region of bone in a small body portion (such as a limb or extremity), using a mini C-arm x-ray fluoroscopic imaging system to acquire the data from which the BMD is calculated. Apparatus for performing the method includes a tray for positioning the small body portion in the x-ray beam path of the imaging system and a sample of bone of predetermined density supported by the tray in side-by-side relation to the selected region of bone.
    Type: Grant
    Filed: January 19, 1999
    Date of Patent: August 28, 2001
    Assignee: Hologic, Inc.
    Inventors: Jay A. Stein, Howard P. Weiss, Vincent E. Quinn, John A. Shepherd, Kevin E. Wilson, Joel Weinstein
  • Patent number: 6233473
    Abstract: True body composition is estimated using a dual-energy, fan-shaped distribution of x-rays and signal processing that corrects for mass magnification and other effects due to the geometry of the measurement system. To avoid inaccuracies due to beam hardening and certain other effects, the thickness of attenuating material along respective raypaths is obtained through using a four-dimensional look-up table derived experimentally from step-wedge measurements. To correct for mass magnification effects due to using a fan-shaped distribution of x-rays, another look-up table and interpolation between table entries are used to convert projected mass to true mass.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: May 15, 2001
    Assignee: Hologic, Inc.
    Inventors: John A. Shepherd, Thomas L. Kelly
  • Patent number: 5949846
    Abstract: A method of measuring bone mineral density (BMD) of a selected region of bone in a small body portion (such as a limb or extremity), using a mini C-arm x-ray fluoroscopic imaging system to acquire the data from which the BMD is calculated. Apparatus for performing the method includes a tray for positioning the small body portion in the x-ray beam path of the imaging system and a sample of bone of predetermined density supported by the tray in side-by-side relation to the selected region of bone.
    Type: Grant
    Filed: February 3, 1997
    Date of Patent: September 7, 1999
    Assignee: Hologic, Inc.
    Inventors: Jay A. Stein, Howard P. Weiss, Vincent E. Quinn, Richard E. Cabral, John A. Shepherd, Kevin E. Wilson
  • Patent number: 5606228
    Abstract: A television vertical timebase circuit includes an arrangement (10, 25, 30, 35, 40, 45) for generating a vertical ramp voltage of first and second slopes corresponding to 4:3 and 16:9 aspect ratios. An arrangement (50,55,65) adds a predetermined voltage to a predetermined portion of the 16:9 ratio ramp voltage such that unwanted visible signals are positioned outside the visible screen area when displaying 16:9 aspect ratio pictures.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: February 25, 1997
    Assignee: Motorola, Inc.
    Inventors: John A. Shepherd, Patrick Douziech
  • Patent number: 4374817
    Abstract: The viscosity of phosphate rock slurries is reduced by incorporating in the slurry both sodium tripolyphosphate and an alkaline material, particularly sodium hydroxide. The combined amount of these two materials required to achieve a given viscosity reduction is significantly lower than the weighted average of the amounts required for each to produce individually the same viscosity reduction. The defined alkaline materials, other than sodium hydroxide, are sodium carbonate, ammonium hydroxide and potassium hydroxide.
    Type: Grant
    Filed: August 21, 1981
    Date of Patent: February 22, 1983
    Assignee: FMC Corporation
    Inventors: Richard L. Lehman, John A. Shepherd