Patents by Inventor John A. Smith

John A. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120215150
    Abstract: This invention uses “targeted apheresis” to treat pregnant women who are at risk of developing eclampsia. “Targeted Apheresis” is a process whereby certain growth factor receptors (sFlt-1) circulating in the blood of a pregnant woman at risk of developing pre-eclampsia are selectively removed by passing the blood through a cartridge containing immobilized anti-sFlt-1 aptamers. The circulating sFlt-1 is bound out by the immobilized anti-sFlt-1 aptamers and the cleaned blood is returned to the patient. Removal of circulating sFlt-1 will diminish the risk of developing eclampsia during pregnancy.
    Type: Application
    Filed: January 17, 2012
    Publication date: August 23, 2012
    Inventors: Henry John Smith, James Roger Smith
  • Patent number: 8248373
    Abstract: A computing system includes one or more input-device user-interface runtime applications to dynamically display images on a dynamic input device. The one or more input-device user-interface runtime applications are executed in a currently active desktop. The computing system further includes a dominant application configured to execute in the currently active desktop. The dominant application is configured to specify an input-device user-interface runtime application corresponding to a current context of the dominant application. The specified input-device user-interface runtime application is configured to dynamically display virtual controls on the dynamic input device. The specified input-device user-interface runtime application is also configured to report activation of the virtual controls to the dominant application.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: August 21, 2012
    Assignee: Microsoft Corporation
    Inventors: Richard Turner, Robert D. Young, Daniel M. Sangster, Scott Robert Honji, Eric Fleegal, Mark Vulfson, Xianfeng Tian, Kevin John Smith
  • Publication number: 20120208740
    Abstract: The present invention discloses a method of preparing a solid form of acetic acid. The method at least includes the steps of combining a solid acid and a metal acetate with a solvent to form a slurry. After a predetermined period of time, a solid form of acetic acid is recovered. The present invention also includes a solid product of acetic acid produced by the above-mentioned method. There is also disclosed a formulation including the solid product of acetic acid according to the present invention. Further, there is disclosed a cleaning system including the formulation according to the present invention.
    Type: Application
    Filed: February 13, 2012
    Publication date: August 16, 2012
    Applicant: ChemLink Laboratories, LLC
    Inventors: Ryan Giffin MOORE, Lucas John SMITH
  • Patent number: 8232273
    Abstract: In one aspect, the present invention provides for a compound of Formula I in which the variable X1a, X1b, X1c, X1d, Q, A, R1, B, L, E, and the subscripts m and n have the meanings as described herein. In another aspect, the present invention provides for pharmaceutical compositions comprising compounds of Formula I as well as methods for using compounds of Formula I for the treatment of diseases and conditions (e.g., cancer, thrombocythemia, etc) characterized by the expression or over-expression of Bcl-2 anti-apoptotic proteins, e.g., of anti-apoptotic Bcl-xL proteins.
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: July 31, 2012
    Assignees: Genentech, Inc., Abbott Laboratories, The Walter and Eliza Hall Institute of Medical Research
    Inventors: Jonathan Bayldon Baell, Chinh Thien Bui, Peter Colman, Peter Czabotar, Danette A. Dudley, Wayne J. Fairbrother, John A. Flygare, Guillaume Laurent Lessene, Chudi Ndubaku, George Nikolakopoulos, Brad Edmund Sleebs, Brian John Smith, Keith Geoffrey Watson, Steven W. Elmore, Lisa A. Hasvold, Andrew M. Petros, Andrew J. Souers, Zhi-Fu Tao, Le Wang, Xilu Wang, Kurt Deshayes
  • Publication number: 20120184541
    Abstract: In one aspect, the present invention provides for a compound of Formula I in which in Formula I, the variables X1, X2a, X2b, X2c, R1, B, L, E, A and the subscript n are as defined herein. In another aspect, the present invention provides for pharmaceutical compositions comprising compounds of Formula I as well as methods for using compounds of Formula I for the treatment of diseases and conditions (e.g., cancer, thrombocythemia, etc) characterized by the expression or over-expression of Bcl-2 anti-apoptotic proteins, e.g., of anti-apoptotic Bcl-xL proteins.
    Type: Application
    Filed: January 10, 2012
    Publication date: July 19, 2012
    Inventors: Jonathan Bayldon Baell, Chinh Thien Bui, Peter Colman, Danette A. Dudley, Wayne J. Fairbrother, John A. Flygare, Guillaume Laurent Lessene, Chudi Ndubaku, George Nikolakopoulos, Carl Steven Rye, Brad Edmund Sleebs, Brian John Smith, Keith Geoffrey Watson, Steven W. Elmore, Andrew M. Petros, Andrew J. Souers, Peter Czabotar
  • Patent number: 8224234
    Abstract: A system for generation of jamming signals and related and techniques are described.
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: July 17, 2012
    Assignee: Raytheon Company
    Inventors: Gary P. Schuster, John A. Smith, Walter F. Schoonover, Jr.
  • Publication number: 20120174924
    Abstract: A conduit for a breathing circuit includes a heater associated, at least in part, with a hydrophilic layer. The purpose of the heater is to evaporate any condensed liquid collecting in the conduit, which is first sucked up by the hydrophilic layer. The heated wick reduces the risk of collected water being passed to the patient and causing choking fits or discomfit. It is preferred that the heated wick lies freely in the conduit to settle at low points in the conduit where condensation may collect.
    Type: Application
    Filed: October 12, 2011
    Publication date: July 12, 2012
    Applicant: FISHER & PAYKEL HEALTHCARE LIMITED
    Inventors: Daniel John Smith, David Peter Baldwin
  • Publication number: 20120160100
    Abstract: The present invention relates to the use of palladium doped ZSM-5 to adsorb volatile organic compounds (VOCs) derived from organic matter, wherein the Si:Al ratio of the ZSM-5 is less than 5 or equal to 100:1, and wherein the palladium doped ZSM-5 is used in an environment comprising less than 10 vol % of oxygen.
    Type: Application
    Filed: July 2, 2010
    Publication date: June 28, 2012
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: Elizabeth Rowsell, Andrew William John Smith, Stephen Poulston
  • Publication number: 20120160059
    Abstract: A method and apparatus for processing metal bearing gases involves generating a toroidal plasma in a plasma chamber. A metal bearing gas is introduced into the plasma chamber to react with the toroidal plasma. The interaction between the toroidal plasma and the metal bearing gas produces at least one of a metallic material, a metal oxide material or a metal nitride material.
    Type: Application
    Filed: December 23, 2011
    Publication date: June 28, 2012
    Applicant: MKS Instruments, Inc.
    Inventors: William M. Holber, John A. Smith, Xing Chen, Donald K. Smith
  • Publication number: 20120159904
    Abstract: A water-soluble pouch suitable for use in machine dishwashing and which comprises a plurality of compartments in generally superposed or superposable relationship, each containing one or more detergent active or auxiliary components, and wherein the pouch has a volume of from about 5 to about 70 ml and a longitudinal/transverse aspect ratio in the range from about 2:1 to about 1:8, preferably from about 1:1 to about 1:4. The water-soluble pouch allows for optimum delivery of dishwashing detergent. A process for the manufacture of multi-compartment pouches and a pack to contain the pouches are also disclosed.
    Type: Application
    Filed: March 1, 2012
    Publication date: June 28, 2012
    Inventors: Tanguy Marie Louis Alexandre Catlin, Rachid Ben Moussa, Timothy Bernard William Kroese, Charles Rupert Gillham, James Iain Kinloch, David John Smith, Alison Lesley Main, Helen Varley
  • Publication number: 20120160757
    Abstract: Systems and associated methods for treating contaminant-containing wastewater are provided. The systems generally include a reducing zone for reducing the oxidation-reduction potential of the water and a clean-up zone comprising zero valent iron for removing at least a portion of the contaminant from the contaminant-containing water. The systems are operable to remove one or more contaminants from the contaminant-containing water and are operable for extended durations without clogging due to the formation of iron hydroxides.
    Type: Application
    Filed: February 29, 2012
    Publication date: June 28, 2012
    Applicant: Alcoa Inc.
    Inventors: Rajat S. Ghosh, Dennis Fulmer, Kevin Kitzman, John Smith
  • Publication number: 20120159718
    Abstract: A water-soluble pouch suitable for use in machine dishwashing and which comprises a plurality of compartments in generally superposed or superposable relationship, each containing one or more detergent active or auxiliary components, and wherein the pouch has a volume of from about 5 to about 70 ml and a longitudinal/transverse aspect ratio in the range from about 2:1 to about 1:8, preferably from about 1:1 to about 1:4. The water-soluble pouch allows for optimum delivery of dishwashing detergent. A process for the manufacture of multi-compartment pouches and a pack to contain the pouches are also disclosed.
    Type: Application
    Filed: March 5, 2012
    Publication date: June 28, 2012
    Inventors: Tanguy Marie Louis Alexandre Catlin, Rachid Ben Moussa, Timothy Bernard William Kroese, Charles Rupert Gillham, James Iain Kinloch, David John Smith, Alison Lesley Main, Helen Varley
  • Publication number: 20120166781
    Abstract: A method and apparatus for securely booting software components in an electronic device to establish an operating environment are described herein. According to an aspect of the invention, software components are to be executed in sequence in order to establish an operating environment of a device. For each software component, a security code is executed to authenticate and verify an executable code image associated with each software component using one or more keys embedded within a secure ROM (read-only memory) of the device and one or more hardware configuration settings of the device. The security code for each software component includes a common functionality to authenticate and verify the executable code image associated with each software component. In response to successfully authenticating and verifying the executable code image, the executable code image is then executed in a main memory of the device to launch the associated software component.
    Type: Application
    Filed: March 2, 2012
    Publication date: June 28, 2012
    Inventors: Joshua de Cesare, Dallas Blake De Atley, Jonathan Jay Andrews, Michael John Smith
  • Patent number: 8206337
    Abstract: This invention relates to apparatus used to heat, humidify and filter insufflated gases to alter the temperature and humidity of gases prior to delivering the gases into a patient The apparatus includes an insufflator, humidifier and gas transportation conduit connected to gas delivery tubing to deliver humidified and heated gases to a body cavity prior to and during a medical procedure. The insufflator an humidifier are contained in the one housing, enabling the housing to be located remote from an operating table. The gas transportation conduit delivers the humidified gases to the body cavity in a flexible tubing having located within, throughout or around it heating apparatus enabling the gas temperature and humidity levels to be maintained from the housing to the patient.
    Type: Grant
    Filed: October 15, 2001
    Date of Patent: June 26, 2012
    Assignee: Fisher & Paykel Healthcare Limited
    Inventors: Michael Joseph Blackhurst, Nina Caroline Batty, Daniel John Smith, Hussein Kadhum
  • Publication number: 20120139139
    Abstract: A water-soluble pouch suitable for use in machine dishwashing and which comprises a plurality of compartments in generally superposed or superposable relationship, each containing one or more detergent active or auxiliary components, and wherein the pouch has a volume of from about 5 to about 70 ml and a longitudinal/transverse aspect ratio in the range from about 2:1 to about 1:8, preferably from about 1:1 to about 1:4. The water-soluble pouch allows for optimum delivery of dishwashing detergent. A process for the manufacture of multi-compartment pouches and a pack to contain the pouches are also disclosed.
    Type: Application
    Filed: February 8, 2012
    Publication date: June 7, 2012
    Inventors: Tanguy Marie Louis Alexandre Catlin, Rachid Ben Moussa, Timothy Bernard William Kroese, Charles Rupert Gillham, James Iain Kinloch, David John Smith, Alison Lesley Main, Helen Varley
  • Publication number: 20120119622
    Abstract: A piezoelectric sensing device is described for measuring material thickness of targets such as pipes, tubes, and other conduits that carry fluids. The piezoelectric sensing device includes a piezoelectric element mounted to a flexible circuit with glass reinforced polyimide C-stage cover layers surrounding a pure polyimide C-stage core.
    Type: Application
    Filed: December 27, 2011
    Publication date: May 17, 2012
    Applicant: General Electric Company
    Inventors: Fred Timothy Matthews, Paul Aloysius Meyer, Matthew Harvey Krohn, Nathan John Smith, Adeodato Maria Vigano
  • Publication number: 20120122771
    Abstract: The present invention relates generally to structural studies of the insulin binding site of the insulin receptor (IR) and the insulin-like growth factor 1 receptor (IGF-1R). More particularly, the present invention relates to the crystal structure of the low affinity insulin binding site of the IR ectodomain comprising the C-terminal region of the IR ?-chain, as well as the corresponding region of IGF-1R, and to methods of using the crystal and related structural information to screen for and design compounds that interact with or modulate the function of IR and/or IGF-1R.
    Type: Application
    Filed: March 9, 2010
    Publication date: May 17, 2012
    Inventors: Michael Colin Lawrence, Brian John Smith, John Gerbrandt Tasman Menting, Colin Wesley Ward
  • Publication number: 20120104164
    Abstract: This invention relates to an improved float for use with an aircraft having water landing capabilities comprising at least one float capable of increasing/decreasing its volume arranged to at least substantially support said aircraft in a floating on water status so that the fuselage of the aircraft is substantially above the water.
    Type: Application
    Filed: May 20, 2010
    Publication date: May 3, 2012
    Inventors: Saxon Grenfell Rudduck, Alan John Smith, Matthew Robert Tetlow
  • Publication number: 20120093660
    Abstract: Efficient impeller or propeller wherein at least one blade in a set of blades on a hub of said impeller is oriented with respect to the tilted plane rotated clockwise or counter clockwise in an axis perpendicular to the longitudinal axis of said impeller. At least one blade in a set of blades of the multi-set impeller may have the same or different sizes or the same or different tilted plane angle compared to at least one blade of the adjacent set or the blade of one set may have the same or different angle as viewed from the second end of the impeller from a reference plane along the longitudinal axis of the impeller compared to the angle of at least one blade of the adjacent set. The invention also includes: blade arrangement for multi-set impeller, inner hub length variations, and hub shapes for better efficiency and utility.
    Type: Application
    Filed: June 30, 2010
    Publication date: April 19, 2012
    Inventor: Mike Richard John Smith
  • Patent number: D661597
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: June 12, 2012
    Assignee: Conopco, Inc.
    Inventors: Benjamin Phalan Oates, Neil John Smith