Patents by Inventor John A. Weidanz

John A. Weidanz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TCR mimic antibodies as vascular targeting tools
    Patent number: 9555108
    Abstract: The present invention includes a method of delivering a therapeutic agent into and across an endothelial cell (EC) in a subject in need thereof, comprising: attaching to a T Cell receptor mimic (TCR mimic) an active agent to form a therapeutic agent; and administering to the subject the therapeutic agent in a pharmaceutically acceptable carrier, wherein the therapeutic agent effectively crosses the EC microvascular barrier. Furthermore, the present invention relates to methods of treating diseases (particularly neuronal diseases) or conditions comprising identifying a subject in need of such a treatment and administering to said subject a composition comprising a TCR mimic conjugated to an active agent.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: January 31, 2017
    Assignee: Texas Tech University System
    Inventors: John A. Weidanz, Ulrich Bickel
  • TCR Mimic Antibodies as Vascular Targeting Tools
    Publication number: 20140134191
    Abstract: The present invention includes a method of delivering a therapeutic agent into and across an endothelial cell (EC) in a subject in need thereof, comprising: attaching to a T Cell receptor mimic (TCR mimic) an active agent to form a therapeutic agent; and administering to the subject the therapeutic agent in a pharmaceutically acceptable carrier, wherein the therapeutic agent effectively crosses the EC microvascular barrier. Furthermore, the present invention relates to methods of treating diseases (particularly neuronal diseases) or conditions comprising identifying a subject in need of such a treatment and administering to said subject a composition comprising a TCR mimic conjugated to an active agent.
    Type: Application
    Filed: March 23, 2012
    Publication date: May 15, 2014
    Applicant: TEXAS TECH UNIVERSITY SYSTEM
    Inventors: John A. Weidanz, Ulrich Bickel
  • TCR Mimic Antibodies as Vascular Targeting Tools
    Publication number: 20140134241
    Abstract: The present invention includes a method of delivering a therapeutic agent into and across an endothelial cell (EC) in a subject in need thereof, comprising: identifying a subject in need for treatment of a cancer in the brain; attaching to a TCR mimic an active agent to form a therapeutic agent; and administering to the subject the therapeutic agent in a pharmaceutically acceptable carrier, wherein the therapeutic agent effectively crosses the blood-central nervous system microvascular barrier.
    Type: Application
    Filed: November 12, 2013
    Publication date: May 15, 2014
    Applicant: TEXAS TECH UNIVERSITY SYSTEM
    Inventors: John A. Weidanz, Ulrich Bickel