Patents by Inventor John Afflitto
John Afflitto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5368845Abstract: An antiplaque composition comprising a bacteriocin such as nisin and a polyphosphonate.Type: GrantFiled: January 7, 1993Date of Patent: November 29, 1994Assignee: Colgate Palmolive CompanyInventors: Abdul Gaffar, John Afflitto, Malathy Subramanian
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Patent number: 5344641Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, wherein said antiplaque agent is substantially completely dissolved in saliva present during tooth and gum cleaning in a solubilizing agent therefor. The solubilizing agent may be a humectant polyol such as propylene glycol, dipropylene glycol and hexylene glycol; a cellosolve such as methyl cellosolve and ethyl cellosolve; a vegetable oil or wax containing at least about 12 carbon atoms in a straight chain such as olive oil, castor oil and petrolatum; or an ester such as ethyl acetate, amyl acetate, glyceryl tristearate and benzyl benzoate.Type: GrantFiled: November 25, 1992Date of Patent: September 6, 1994Assignee: Colgate-Palmolive Co.Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
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Patent number: 5312618Abstract: An oral composition dentifrice containing an orally acceptable vehicle, about 30-75% by weight of a dentally acceptable water-insoluble polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2.sup.1 -hydroxy-diphenyl ether (triclosan) an antibacterial enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, and a surface active agent and/or a flavoring oil.Type: GrantFiled: December 2, 1992Date of Patent: May 17, 1994Assignee: Colgate-Palmolive Co.Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer, Michael Prencipe
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Patent number: 5294431Abstract: An oral composition mouthwash or liquid dentifrice containing an aqueous vehicle acceptable vehicle, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.Type: GrantFiled: October 16, 1992Date of Patent: March 15, 1994Assignee: Colgate-Palmolive Co.Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
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Patent number: 5292526Abstract: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). Antiplaque effectiveness is optimized by the presence of an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.Type: GrantFiled: October 23, 1992Date of Patent: March 8, 1994Assignee: Colgate-Palmolive Co.Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
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Patent number: 5288480Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, about 0.25-0.35% by weight of a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces.Type: GrantFiled: October 21, 1992Date of Patent: February 22, 1994Assignee: Colgate-Palmolive Co.Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
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Patent number: 5275805Abstract: An antiplaque oral composition such as a gel, paste or mouthrinse which is comprised of a vehicle having incorporated therein as the antiplaque agent an effective amount of an antibacterial salicylanilide compound and a surfactant mixture of an anionic surfactant, a polyoxyethylene/polyoxypropylene block copolymer and a taurate salt, the pH of the composition being adjusted to a pH of at least 8.0. An antibacterial-enhancing agent such as an anionic polymeric polycarboxylate which enhances the delivery of the salicylanilide compound to and retention on oral tissue surfaces is optionally incorporated in the composition to improve the efficacy of the salicylanilide compound.Type: GrantFiled: June 11, 1993Date of Patent: January 4, 1994Inventors: Nuran Nabi, Abdul Gaffar, John Afflitto
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Patent number: 5192531Abstract: An oral composition dentifrice containing an orally acceptable vehicle, about 30-75% by weight of a dentally acceptable water-insoluble polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) an antibacterial enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, and a surface active agent and/or a flavoring oil.Type: GrantFiled: September 9, 1991Date of Patent: March 9, 1993Assignee: Colgate-Palmolive CompanyInventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer, Michael Prencipe
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Patent number: 5192530Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, wherein said antiplaque agent is substantially completely dissolved in saliva present during tooth and gum cleaning in a solubilizing agent therefor. The solubilizing agent may be a humectant polyol such as propylene glycol, dipropylene glycol and hexylene glycol; a cellosolve such as methyl cellosolve and ethyl cellosolve; a vegetable oil or wax containing at least about 12 carbon atoms in a straight chain such as olive oil, castor oil and petrolatum; or an ester such as ethyl acetate, amyl acetate, glyceryl tristearate and benzyl benzoate.Type: GrantFiled: September 6, 1991Date of Patent: March 9, 1993Assignee: Colgate-Palmolive CompanyInventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
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Patent number: 5188821Abstract: An oral composition mouthwash or liquid dentifrice containing an aqueous vehicle acceptable vehicle, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.Type: GrantFiled: August 28, 1989Date of Patent: February 23, 1993Assignee: Colgate-Palmolive CompanyInventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
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Patent number: 5180578Abstract: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). Antiplaque effectiveness is optimized by the presence of an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.Type: GrantFiled: February 19, 1991Date of Patent: January 19, 1993Assignee: Colgate-Palmolive CompanyInventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
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Patent number: 5178851Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, about 0.25-0.35% by weight of a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces.Type: GrantFiled: February 14, 1991Date of Patent: January 12, 1993Assignee: Colgate-Palmolive CompanyInventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
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Patent number: 5094844Abstract: An oral composition such as a toothpaste (including gel or cream), mouthwash, lozenge, chewing gum or tooth powder containing a calculus-inhibiting amount of a linear molecularly dehydrated polyphosphate salt and, as inhibitor of enzymatic hydrolysis of said polyphosphate salt in saliva, a synthetic polymeric vinyl phosphate. A fluoride-ion providing source may also be present to further inhibit the enzymatic hydrolysis of said polyphosphate salt.Type: GrantFiled: December 20, 1990Date of Patent: March 10, 1992Assignee: Colgate-Palmolive CompanyInventors: Abdul Gaffar, John Afflitto, Sahar F. Smith
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Patent number: 5032386Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, about 0.25-0.35% by weight of a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces.Type: GrantFiled: August 25, 1989Date of Patent: July 16, 1991Assignee: Colgate-Palmolive CompanyInventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
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Patent number: 4843099Abstract: Ibuprofen, pharmaceutically acceptable salt thereof or lower alkyl C.sub.1-6 ester thereof, in solution in periodontal gum device comprising elongated handle member terminating proximally in a flexible tip portion provided with an aperture for discharge of the solution which is effective to reduce gingival inflammation and swelling.Type: GrantFiled: July 20, 1987Date of Patent: June 27, 1989Assignee: Colgate-Palmolive CompanyInventors: Abdul Gaffar, John Afflitto
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Patent number: 4826675Abstract: An Anticalculus Oral Composition, typically a mouthwash or dentifrice gel, containing compound having C-O-P bonds, such as phytic acid or an alkali metal (including ammonium) salt thereof as anticalculus agent, homogeneously distributed in a dentally acceptable oral vehicle. Also, present to inhibit enzymatic hydrolysis of the phytic compound and to promote caries reduction is an alkali metal fluoride.Type: GrantFiled: February 17, 1988Date of Patent: May 2, 1989Assignee: Colgate-Palmolive CompanyInventors: Abdul Gaffar, Shek-Hong Lau, John Afflitto