Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: The present invention provides a compound, preferably a peptide, having the following characteristics: a) consisting of 9 amino acids in a linear arrangement; b) of those 9 amino acids, 5 are cationic and 4 have a lipophilic R group; c) at least one of said 9 amino acids is a non-genetically coded amino acid (e.g. a modified derivative of a genetically coded amino acid); and optionally d) the lipophilic and cationic residues are arranged such that there are no more than two of either type of residue adjacent to one another; and further optionally e) the molecule comprises two pairs of adjacent cationic amino acids and one or two pairs of adjacent lipophilic residues; for use in the treatment of a tumour by combined, sequential or separate administration with an immune checkpoint inhibitor. The present invention further provides pharmaceutical packs or compositions comprising these active agents and methods of treating a tumour comprising administration of these active agents.

Abstract: Interlayers that exhibit superior properties and that provide desirable optical properties when incorporated into laminates, such as windshields, windows or other glazings containing a holographic optical element (HOE) are disclosed. The interlayers, when used in a laminate in conjunction with the HOE film, maintain and do not detract from the HOE film properties.

Abstract: A system for development of an Artificial Intelligence (AI) model while protecting sensitive user information includes: a confidential computing environment in which original prompts to the AI model written by users are collected; a trained synthetic prompt generator to generate synthetic prompts based on the original prompts, wherein the synthetic prompt generator generates anonymized synthetic prompts without sensitive user information identifiable from the original prompts; and a developer computing environment in which the synthetic prompts are submitted to the AI model under development to generate a dataset that includes the synthetic prompts and corresponding AI model output for analysis to determine updates for the AI model while protecting the sensitive user information of actual users.

Abstract: The present disclosure is directed to methods and techniques for gob-pressing a glass part of challenging geometries, such as large surfaces with thin thickness as well as features positioned far from a centroid of the part.

Abstract: Devices, systems and methods are provided for subdermal tissue tightening through soft tissue coagulation and for use in cosmetic surgery applications. The devices, systems and methods of the present disclosure may be used for a minimally invasive application of helium-based cold plasma energy to subcutaneous tissue for the purpose of tightening lax tissue.

Abstract: A safety automation system for an occupiable structure includes a computing management system, a first detection device, and a second detection device. The management system includes a computer processor, and a computer readable storage medium configured to run embedded software, The first detection device is adapted to detect a hazard condition and output an associated hazard condition detected signal to the computing management system. The second detection device is adapted to detect the presence of an occupant in the occupiable structure and the occupant's proximity to the first detection device, and output an occupied signal to the computing management system. The computing management system adjusts the sensitivity of the first detection device based on occupancy and proximity of the occupant to the first detection device.

Abstract: A jet pump slip joint repair assembly includes at least one clamp and a bushing configured to be inserted in a bore of a diffuser and to surround a portion of an inlet mixer. The clamp includes a gripping surface and a gripping collar. The bushing includes a generally cylindrical sidewall, the sidewall configured to surround the portion of the inlet mixer, a grooved flange on an upper surface of the sidewall, at least one cutout between adjacent portions of the grooved flange, and a groove on an inner, bottom surface of the sidewall. The assembly also includes a seal in the groove. The seal is flexible and formed of a metallic material. The seal is configured to be compressed when the at least one clamp engages the bushing.

Abstract: A safety automation system for an occupiable structure includes a computing management system, a first detection device, and a second detection device. The management system includes a computer processor, and a computer readable storage medium configured to run embedded software, The first detection device is adapted to detect a hazard condition and output an associated hazard condition detected signal to the computing management system. The second detection device is adapted to detect the presence of an occupant in the occupiable structure and the occupant's proximity to the first detection device, and output an occupied signal to the computing management system. The computing management system adjusts the sensitivity of the first detection device based on occupancy and proximity of the occupant to the first detection device.

Abstract: A safety automation system for an occupiable structure includes a computing management system including a computer processor, and a computer readable storage medium configured to run embedded software and cloud server software. A fire detection device of the automation system is adapted to detect a fire condition and output an associated fire condition detected signal to the computing management system. A condition deterrence device is configured to accept a wireless command signal from the computing management system associated with the fire condition detected signal and for actuating an appliance to at least reduce risk presented by the condition.

Abstract: An integrated detection and suppression system includes a fiber harness having at least one fiber optic cable for transmitting light defining at least one node arranged to measure one or more conditions. A light source is operably connected to the fiber harness to transmit light along the fiber harness to the at least one node. A control system is operably coupled to the fiber harness such that scattered light associated with the node is transmitted to the control system, wherein the control system analyzes the scattered light to determine at least one of a presence and magnitude of the one or more conditions. At least one suppressant outlet is associated with at least one node and is operably connected to the control system configured to initiate a response for the delivery of a volume of suppressant through a suppressant outlet associated with a particular node.

Abstract: The present invention relates to a collector composition containing 80 to 100 wt % of at least one alkylethermonoamine, less than 20 wt % alkyletherdiamine, all wt % based on total weight of all amine components, and wherein the alkylethermonoamine contains between 60 and 93% isotridecyl(C13)etherpropylamine, 5 and 30% of isododecyl(C12)etherpropylamine, 0 and 10% of isoundecyl(C11)-etherpropylamine, 0 and 10% of isodecyl(C10)etherpropylamine, 2 and 10% tetradecyl(C14) etherpropylamine, all % being based on total weight of alkylethermonoamine and the use thereof in a process to treat iron ore.

Abstract: The application relates to compositions comprising di-fatty-alkyl or -alkenyl polyalkylamines of the general formula (I) or (II), to a process for their preparation which involves a cyanoethylation step and a hydrogenation step, and their use as demulsifiers for oil-in-water emulsions, corrosion inhibitor, fuel additive, anti-scaling agent, asphalt additive, enhanced oil recovery agent for oil-wells, cutting-oil additive, and anti-static agent. The product show good performance combined with a favourable viscosity profile.

Abstract: A jet pump slip joint repair assembly includes at least one clamp and a bushing configured to be inserted in a bore of a diffuser and to surround a portion of an inlet mixer. The clamp includes a gripping surface and a gripping collar. The bushing includes a generally cylindrical sidewall, the sidewall configured to surround the portion of the inlet mixer, a grooved flange on an upper surface of the sidewall, at least one cutout between adjacent portions of the grooved flange, and a groove on an inner, bottom surface of the sidewall. The assembly also includes a seal in the groove. The seal is flexible and formed of a metallic material. The seal is configured to be compressed when the at least one clamp engages the bushing.

Abstract: A LED light fixture includes an LED assembly that emits light when energized through an electrical path. An inner optic is positioned to receive the light. The inner optic comprises a lens that emits the light from the inner optic with a wide beam angle. A reflector is positioned to receive the light emitted from the inner optic. An inner reflector is positioned to asymmetrically reflect the light from the inner optic relative to the reflector.

Abstract: Devices, systems and methods are provided for subdermal tissue tightening through soft tissue coagulation and for use in cosmetic surgery applications. The devices, systems and methods of the present disclosure may be used for a minimally invasive application of helium-based cold plasma energy to subcutaneous tissue for the purpose of tightening lax tissue.

Abstract: An integrated detection and suppression system includes a fiber harness having at least one fiber optic cable for transmitting light defining at least one node arranged to measure one or more conditions. A light source is operably connected to the fiber harness to transmit light along the fiber harness to the at least one node. A control system is operably coupled to the fiber harness such that scattered light associated with the node is transmitted to the control system, wherein the control system analyzes the scattered light to determine at least one of a presence and magnitude of the one or more conditions. At least one suppressant outlet is associated with at least one node and is operably connected to the control system configured to initiate a response for the delivery of a volume of suppressant through a suppressant outlet associated with a particular node.

Abstract: A jet pump slip joint repair assembly includes at least one clamp and a bushing configured to be inserted in a bore of a diffuser and to surround a portion of an inlet mixer. The clamp includes a gripping surface and a gripping collar. The bushing includes a generally cylindrical sidewall, the sidewall configured to surround the portion of the inlet mixer, a grooved flange on an upper surface of the sidewall, at least one cutout between adjacent portions of the grooved flange, and a groove on an inner, bottom surface of the sidewall. The assembly also includes a seal in the groove. The seal is flexible and formed of a metallic material. The seal is configured to be compressed when the at least one clamp engages the bushing.

Abstract: The present invention relates to a process to treat magnetite ore containing less than 15 wt % of silica on total ore, the process containing a step of (froth) flotating in the presence of a collector composition that contains 80 to 100 wt % of at least one alkylethermonoamine, less than 20 wt % alkyletherdiamine, all wt % based on total weight of all amine components, and wherein the alkylethermonoamine is an alkylethermonoamine with a degree of branching higher than 1, the alkyl containing 11 to 17 carbon atoms, and further relates to the collector composition that can be used in the process.

Abstract: A safety automation system (20) for an occupiable structure and method of operation includes a plurality of detection devices (30) to facilitate the detection of a hazard condition and output a hazard detected signal to a computing management system (44) that may be a cloud computing system. The management system includes a computer processor (46), and a computer readable storage medium (48) capable of generating various notifications to a mobile user interface device (32).