Patents by Inventor John Andrew Walker, II

John Andrew Walker, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for modulating CRISPR activity
    Patent number: 11884918
    Abstract: Provided herein are polynucleotides comprising sequence configured to bind to a CRISPR effector protein. Modulation of one or more modifications of the polynucleotides can be used to tune the activity of CRISPR effector proteins complexed with the polynucleotides.
    Type: Grant
    Filed: July 23, 2021
    Date of Patent: January 30, 2024
    Assignee: Synthego Corporation
    Inventors: Reed Kelso, Jared Carlson-Stevermer, Sahil Joshi, Travis Maures, Anastasia Kadina, John Andrew Walker, II
  • Systems and Methods for Modulating CRISPR Activity
    Publication number: 20220073912
    Abstract: Provided herein are polynucleotides comprising sequence configured to bind to a CRISPR effector protein. Modulation of one or more modifications of the polynucleotides can be used to tune the activity of CRISPR effector proteins complexed with the polynucleotides.
    Type: Application
    Filed: July 23, 2021
    Publication date: March 10, 2022
    Inventors: Reed Kelso, Jared Carlson-Stevermer, Sahil Joshi, Travis Maures, Anastasia Kadina, John Andrew Walker, II
  • Stabilized CRISPR Complexes
    Publication number: 20220056436
    Abstract: Provided herein are polynucleotides and CRISPR effector proteins configured to be covalently bound together in a CRISPR complex. The polynucleotides can be further modified to modulate the activity of the CRISPR complex. Modification of the polynucleotide and CRISPR effector protein can be used to improve the efficacy of target binding and/or cleavage.
    Type: Application
    Filed: July 23, 2021
    Publication date: February 24, 2022
    Inventors: Travis Maures, Jared Carlson-Stevermer, Sahil Joshi, Reed Kelso, Anastasia Kadina, John Andrew Walker, II
  • POLYMER SYNTHESIS SYSTEM AND METHOD
    Publication number: 20210047668
    Abstract: The present invention provides improved automated systems and methods for synthesis of biopolymers including DNA and RNA. The automated systems and methods represent a number of improvements over existing systems for multiplex synthesis of biopolymers in a combinatorial fashion.
    Type: Application
    Filed: August 10, 2020
    Publication date: February 18, 2021
    Inventors: Paul Dabrowski, Fabian Gerlinghaus, Reed Kelso, John Andrew Walker, II
  • BIOPOLYMER SYNTHESIS SYSTEM AND METHOD
    Publication number: 20190076814
    Abstract: The present invention provides improved automated systems and methods for synthesis of biopolymers including DNA and RNA. The automated systems and methods represent a number of improvements over existing systems for multiplex synthesis of biopolymers in a combinatorial fashion.
    Type: Application
    Filed: September 13, 2018
    Publication date: March 14, 2019
    Inventors: Paul Dabrowski, Fabian Gerlinghaus, Reed Kelso, John Andrew Walker, II